A Review on Microspheres: Types, Method of Preparation, Characterization and Application

2021 ◽  
pp. 149-155
Author(s):  
Gurunath S. Dhadde ◽  
Hanmant S. Mali ◽  
Indrayani D. Raut ◽  
Manoj M. Nitalikar ◽  
Mangesh A. Bhutkar
Keyword(s):  
Drug Delivery ◽  
Dosage Form ◽  
Immediate Release ◽  
Central Place ◽  
Dosage Forms ◽  
The Novel ◽  
Different Types ◽  
Novel Drug Delivery System ◽  
Novel Drug

The microspheres are one of the novel drug delivery system in which effective therapeutic alternative to conventional or immediate release single-unit dosage forms. Microspheres can be characterized as solid, diameter having between 1–1000μm.there are different types of microsphere explained. These microspheres prepared and fill them in a hard gelatin or compress them directly. The microspheres which are prepared by using different technique that are changes their effectiveness and administration of the dosage form as compare to conventional dosage form. Microsphere will be evaluated by using different methods that analyses quality of the microsphere. The microspheres which will get central place in novel drug delivery in future.

A REVIEW ON HERBAL EXCIPIENTS

2021 ◽  
pp. 05-08
Author(s):  
Arpita singh ◽  
Nidhi Gupta ◽  
Amresh Gupta
Keyword(s):  
Dosage Form ◽  
Low Cost ◽  
Dosage Forms ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients ◽  
Gum Acacia ◽  
Different Types ◽  
Great Merit ◽  
Novel Drug

The Herbal or natural excipients have great merit over their synthetic analogs as these are non-toxic, low-cost, and freely obtainable. The performance of the excipients partly determines the quality of the medicines. The plant acquired gums, mucilage from the natural origin for example carrageenan, thaumatin, lard, storax, agar, gum acacia, tragacanth, and excipients.  They can also be easily altered to meet the specific needs, thereby being a potent many more to name comply with many requirements of the pharmaceutical and economic vehicle for transporting active pharmaceutical ingredients in the formulation. Thus present study aims to throw light on the probable of natural excipients which can be present to be used as a diluent, binder, disintegrant as well as lubricant in different types of formulations as they are biocompatible and capable of giving additional nutrition to the developed dosage form. This article gives an overview of natural excipients which are used in conventional dosage forms as well as novel drug delivery systems.

A Review on Fast Dissolving Tablet

2017 ◽  
Vol 8 (03) ◽  
Author(s):  
Sagar T. Malsane ◽  
Smita S. Aher ◽  
R. B. Saudagar
Keyword(s):  
Drug Delivery ◽  
Patient Compliance ◽  
Research Area ◽  
Oral Route ◽  
Dosage Forms ◽  
The Novel ◽  
The Past ◽  
Orally Disintegrating Tablets ◽  
Novel Drug ◽  
Experience Difficulty

Oral route is presently the gold standard in the pharmaceutical industry where it is regarded as the safest, most economical and most convenient method of drug delivery resulting in highest patient compliance. Over the past three decades, orally disintegrating tablets (FDTs) have gained considerable attention due to patient compliance. Usually, elderly people experience difficulty in swallowing the conventional dosage forms like tablets, capsules, solutions and suspensions because of tremors of extremities and dysphagia. In some cases such as motion sickness, sudden episodes of allergic attack or coughing, and an unavailability of water, swallowing conventional tablets may be difficult. One such problem can be solved in the novel drug delivery system by formulating “Fast dissolving tablets” (FDTs) which disintegrates or dissolves rapidly without water within few seconds in the mouth due to the action of superdisintegrant or maximizing pore structure in the formulation. The review describes the various formulation aspects, superdisintegrants employed and technologies developed for FDTs, along with various excipients, evaluation tests, marketed formulation and drugs used in this research area.

Short Review on Novel Dosage Form

2021 ◽  
pp. 301-303
Author(s):  
Tushar N. Sonawane ◽  
Pradip D. Dhangar ◽  
Sagar D Patil ◽  
Azam Z. Shaikh
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Delivery Systems ◽  
Drug Effects ◽  
Short Review ◽  
Delivery Systems ◽  
The Novel ◽  
Novel Drug Delivery System ◽  
Novel Drug

Novel Drug Delivery Systems are one of the widely use delivery system in the presence scenario. Novel drug delivery system is a novel approach to drug delivery that addresses the limitations of the traditional drug delivery systems. In the form of a Novel Drug Delivery System an existing drug molecule can get a new life. The novel drug delivery system is Increases bioavailability and it Can be used for long-term treatments of chronic illness, Sustained maintenance of plasma drug levels as well as it Decreased adverse drug effects in the total amount of drugs required thus reducing side effects it Improved patient compliance due to reduction in number and frequency of doses required. There is less damage sustained by normal tissue due to targeted drug delivery. In this paper our main focus to give the throughout knowledge of some newer (Novel drug delivery system) to understand the concept of the Novel dossage form.

scholarly journals Topical Delivery of Aceclofenac: Challenges and Promises of Novel Drug Delivery Systems

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Kaisar Raza ◽  
Manish Kumar ◽  
Pramod Kumar ◽  
Ruchi Malik ◽  
Gajanand Sharma ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Side Effects ◽  
Topical Delivery ◽  
World Population ◽  
The Novel ◽  
Inflammatory Drugs ◽  
The Common ◽  
Novel Drug ◽  
Regulatory Challenges

Osteoarthritis (OA), a common musculoskeletal disorder, is projected to affect about 60 million people of total world population by 2020. The associated pain and disability impair the quality of life and also pose economic burden to the patient. Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely prescribed in OA, while diclofenac is the most prescribed one. Oral NSAIDs are not very patient friendly, as they cause various gastrointestinal adverse effects like bleeding, ulceration, and perforation. To enhance the tolerability of diclofenac and decrease the common side effects, aceclofenac (ACE) was developed by its chemical modification. As expected, ACE is more well-tolerated than diclofenac and possesses superior efficacy but is not completely devoid of the NSAID-tagged side effects. A series of chemical modifications of already planned drug is unjustified as it consumes quanta of time, efforts, and money, and this approach will also pose stringent regulatory challenges. Therefore, it is justified to deliver ACE employing tools of drug delivery and nanotechnology to refine its safety profile. The present review highlights the constraints related to the topical delivery of ACE and the various attempts made so far for the safe and effective topical delivery employing the novel materials and methods.

scholarly journals A Comprehensive Review On Pelletization Technology: A Novel Strategy For Formulation Development

2021 ◽  
Vol 001 (03) ◽  
Author(s):  
Akshay Parihar ◽  
Bhupendra Prajapati ◽  
Himanshu Paliwal
Keyword(s):  
Drug Delivery ◽  
Oral Drug Delivery ◽  
Dosage Forms ◽  
Oral Drug ◽  
The Novel ◽  
Formulation Development ◽  
Oral Drug Delivery System ◽  
Bioactive Agents ◽  
Novel Strategy ◽  
Novel Drug

Pelletization technology is gaining very much attention in present times as it has provided a competent pathway for the oral drug delivery system manufacturing. Pellets offers many biopharmaceuticals as well as technological recompenses over the conventional dosage forms. Pellets offer required strength for dose which can be blended for the delivery of incompatible bioactive agents and helps in providing different release profiles. In this review we will be discussing the extensively used techniques of pelletization, extrusion and spheronization in detail with their methods and applications in the field of pharmacy as a competent pathway for the novel drug delivery systems.

Niosomes: The Current and Future perspectives in Drug Delivery System

2021 ◽  
pp. 3961-3966
Author(s):  
Bhupendra Singh ◽  
Pooja Sharma ◽  
Sujit Bose ◽  
Jyoti Thakur ◽  
Geetanjali Saini ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Dosage Form ◽  
Ionic Surfactants ◽  
Future Perspectives ◽  
Conventional Drug ◽  
Dosing Frequency ◽  
Novel Drug Delivery System ◽  
Novel Drug

There are many problems with the conventional dosage form of various drugs and one of them is dosing frequency in which patients have to take the drug again and again throughout the day which is very difficult mainly for the elder patient. So, to overcome this problem the approach of a novel drug delivery system (NDDS) is used to replace the conventional drug delivery system. NDDS mainly deals with sustained release of drugs which is effective to reduce the dosing frequency. Niosome is one of the best approaches of a novel drug delivery system, in which the drug in solution form is enclosed in vesicle which is made up of non-ionic surfactants. In the case of liposome which is another part of NDDS vesicles is made up of phospholipids. Niosome formulation is a powerful tool to resolve the issue of insolubility and the low bioavailability of drugs. This paper overviews the various methods of preparation of Niosome along with its pharmaceutical applications.

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