Effect of Metabolism of Carbohydrate in Mammalian Tissues and Tumors on The Level of Enzymes Involved in Direct Oxidative Pathway

2021 ◽  
Vol 15 (10) ◽  
pp. 3290-3292
Author(s):  
Saleha Akram Nizami ◽  
Sabahat Fatima ◽  
Anas Khalil ◽  
Gul-E- Rana ◽  
Noor-Ul- Ain ◽  
...  
Keyword(s):  
Intact Cell ◽  
Cross Sectional Study ◽  
Mammalian Tissue ◽  
Sectional Study ◽  
Cross Sectional ◽  
Normal Tissues ◽  
Oxidative Pathway ◽  
Mammalian Tissues ◽  
Glass Homogenizer ◽  
The Subject

Introduction: Literature review has revealed that the distribution of the enzymes of 6-phospo-gluconate dehydrogenase activities of some acetone derived tissues in animal tissue have so far not been investigated systematically. This leaves a gap for further investigation to explore the subject matter deeply. Method: Barium salts of D-Glucose 6-phosphate (0 6-P), 6-phosphogluconate (6-PO) and D-ribose 5-phosphate (R 5-P) are available and were used in our study. (TNP) triphosphopyridine was prepared and analyzed; its composition was 75% TNP without (DNP) diphosphopyridine nucleotide. Ice-cold isotone KCL (0-15M-KCL with 8ml, 0-02M-KHCO3) was disintegrated in 09 parts. It is done in a potter glass homogenizer or in a Nelco homogenizer. This is followed by centrifuging and dialysis of the supernatants. Heparinized blood 10ml was used for erythrocyte hemolysis, which was diluted with 10ml of water. 01 part of haemolysate was treated with 9 parts of isotonic KCI. Spectroscope is used to determine the dehydrogenase activity of dialyzed tissue. The method followed was of Glock and McLean. Study Design: Quantitative, cross sectional study. Settings: Institute of Biochemistry, Gulab Devi Educational Complex, Lahore Duration: 01 Year i.e. 1st July 2020 to 30th June 2021. Results: Enzymes activities of 6-PG dehydrogenase and Gluco-6- phospo dehydrogenase mentioned in table 1&2 in normal mammalian tissue and mammary glands. The results obtained on the tumour cells are given in table 3. These Values are within the limits in normal tissues whereas it becomes on higher side in lymphomas and sarcomas. Conclusion: This study shows some limitation that the maximum enzymic activities are determined, whereas in the intact cell other regulatory factors probably limit or control the activity of this pathway. Keywords: Gluco-6- phospodehydrogenase, 6-PG dehydrogenase, oxidative pathway, Ribose 5-Pentose, mammalian tissue

scholarly journals Awareness of dissection skills and tools session in preparing first MBBS learners for cadaveric dissection in medical school a qualitative analysis

2021 ◽  
Vol 8 (2) ◽  
pp. 94-97
Author(s):  
TLS Gowri ◽  
M Ramadevi ◽  
Aparna Vedapriya ◽  
V Janaki ◽  
Jana Siva Koti Srinivasa Rao ◽  
...  
Keyword(s):  
Initial Phase ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Validated Questionnaire ◽  
Post Test ◽  
Chi Square Test ◽  
The Subject

Qualitative dissections require knowledge of dissection tool kit and dissection skills which acquired will allow dissector to take care for cadaveric donor while acquiring the experience and knowledge of a successful dissection. This promotes the researcher to equip the learner in initial phase with dissection skills and tools.The main objective of the study is to analyse the learner prior and after interventional sessions as to how effective the session would be helpful in improving the quality and participation of learners in dissection. A qualitative prospective cross-sectional study was done in 168 Learners of I MBBS by an interventional session on the topic through General lecture and demonstration. Learners were assessed prior and after the interventional session by same validated questionnaire. Perceptions of learners were also taken. The obtained data were compared and its significance was analysed by Chi-square test using Epi info 7.1 software.The pre and post-test scores showed a significant improvement of 64 percent on average with p value less than 0.001 indicating that the session was fruitful. 80% of learners also opined that the session stimulated interest in the subject and improved their dissection skills.An interventional session on “Awareness of dissection skills and tools” in the initial phase would increase the Learners performing quality dissections with ease. This would also help the learner to acquire better independent surgical skills and understanding in clinical phases of learning and therefore would recommend it in early phase of I MBBS Anatomy.

scholarly journals Analyzing the Enablers and Barriers in Procurement affecting Supply Chain Resilience

2020 ◽  
Vol 7 (2) ◽  
pp. 403-414
Author(s):  
Syed Muhammad Wasif ◽  
Muhammad Asim ◽  
Salman Manzoor
Keyword(s):  
Supply Chain ◽  
Risk Mitigation ◽  
Cross Sectional Study ◽  
Present System ◽  
Sectional Study ◽  
Total Risk ◽  
Cross Sectional ◽  
Supply Chain Resilience ◽  
Global Event ◽  
The Subject

Supply chain professionals are aware that the performance of any supply chain lies in their ability to effectively and consistently handle risks therefore; emerging the disciplines of risk management and supply chain management in an industry. This study highlights the importance of enablers and barriers in performing supply chain in a disruptive global event. And advances an interdisciplinary understanding of the concept resilience. Managers can take proactive steps to address and implement primary causal enables of risk mitigation into practice for reducing total risk impacts of the supply chain. The objective of this paper was to conceptualize the effect of enablers and barriers on the supply chain resilience. This paper provides guidance for companies seeking to supply chain resilience and identifies which enablers can support and which barriers to overcome. We conducted an observational cross-sectional study and applied a self-designed survey questionnaire to 358 participants to assist their knowledge and experience on the enablers and barriers that affect supply chain sourcing, keeping in view the concept of resilience. Th data was collected from supply chain departments of different industries i.e. government and private sectors. Among 358 participants, 82.1%were male and 17.4%were females among which 53.4% were aware about the importance of the supply chain resilience despite of working in supply chain department. It was found during the survey that the most important enabler which have profound effect on the supply chain resilience was Trust 63% and the barrier was Lack of knowledge 46.6% of the subject. We attempted our exceptional to capture all the possible enablers/barriers in this paper. However, as time will advance, alternatives will likely develop leaving space for their integration in the present system.

scholarly journals Evaluation of Radiographers’ Knowledge, Attitudes, and Performance Regarding Gonadal Shielding in Diagnostic Radiology Examinations: Southern Khorasan Province Hospitals of Iran

2021 ◽  
Vol 13 (4) ◽  
Author(s):  
Nima Hamzian ◽  
Saeed Asadian ◽  
Asiye Golestani ◽  
Hassan Zarghani
Keyword(s):  
Ionizing Radiation ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
X Ray ◽  
A Value ◽  
Pelvic Area ◽  
Pelvic Radiography ◽  
The Subject ◽  
And Performance

Background: Nowadays, ionizing radiation is increasingly used in medicine. One of the most frequent X-ray examinations is pelvic radiography. Gonads are susceptible in the pelvic area. Gonadal shielding (GS) is a useful method to reduce the received dose by gonads. Despite the benefits of using gonadal shielding, it is rarely used by radiographers. Methods: This cross-sectional study was carried out in ten governmental hospitals with 300 radiographs. Results: The radiographers’ knowledge of using GS had a value equal to 59.1%. However, the radiographers did not have enough information on the subject, although their awareness about the significance of GS was acceptable. Conclusions: Although the radiographers believed in the necessity of using GS for pelvic, abdominal, and spine examinations, they used no shields.

scholarly journals Nurse Prescribing-Readiness of Polish Nurses to Take on New Competencies—A Cross-Sectional Study

Healthcare ◽  
2019 ◽  
Vol 7 (4) ◽  
pp. 151
Author(s):  
Anna Bartosiewicz ◽  
Andrzej Różański
Keyword(s):  
Cross Sectional Study ◽  
Development Programs ◽  
Sectional Study ◽  
Learning And Development ◽  
Cross Sectional ◽  
Self Evaluation ◽  
Professional Goals ◽  
Nurse Prescribing ◽  
Readiness To Learn ◽  
The Subject

From January 2016, nurses in Poland received new competencies for prescribing. The work is the first in Poland to elaborate on the subject of nurses’ readiness to learn and develop in the context of new nursing rights regarding autonomous prescription of medication and continuation of the prescription for medication. The aim of the study is to analyze the readiness of Polish nurses to learn and develop in the context of new competencies to write prescriptions. The research was conducted among 756 nurses. The standardized questionnaire (Readiness of Employees for Learning and Development) was used. For all subscales of readiness for learning and development, average scores prevailed. The readiness to write prescriptions was significantly related to the level of openness to changes in the work environment (A1 scale), self-evaluation of past educational development (C5 scale) and educational and professional goals alignment- employee and company (scale D2) and increasing the readiness of nurses to practice all of the aforementioned agents, in particular medical devices. The readiness of nurses to learn and develop at all levels of the subscales was on an average level. Younger nurses, with a shorter seniority, having higher education and additional qualifications had a higher readiness to prescribe medications and write prescriptions. The higher readiness for learning and development was matched by a greater readiness to prescribe. The results obtained can be used to plan training and courses, as well as to create special pro-development programs, which may increase the nurses’ involvement in personal and professional development.

Objective Assessment of Corneal Backscattered Light in Myopic, Hyperopic, and Emmetropic Children

2021 ◽  
Author(s):  
Pinar Nalcacioglu ◽  
Emine Sen ◽  
Emre Aydemir ◽  
Hasan Kiziltoprak ◽  
Hakan Halit Yasar
Keyword(s):  
Objective Assessment ◽  
Cross Sectional Study ◽  
Spherical Equivalent ◽  
Central Layer ◽  
Sectional Study ◽  
Cross Sectional ◽  
Corneal Densitometry ◽  
Scheimpflug Imaging ◽  
Annular Zone ◽  
The Subject

Abstract Purpose: To determine the corneal densitometry values by using Scheimpflug imaging in myopic, and hyperopic children and to compare the results with emmetropic children.Methods: The corneal densitometry measurements of the subject were obtained with Pentacam Scheimpflug tomography. The values were automatically measured in standardized grayscale units (GSU) over an area 12 mm in diameter, which was subdivided into 4 annular concentric zones (0-2 mm, 2-6 mm, 6-10 mm, 10-12 mm) and 3 corneal depths (anterior layer: anterior 120 µm; central layer: from 120 µm to the last 60 µm; posterior layer: last 60 µm). In addition, we evaluated the correlation between spherical equivalence and anterior corneal morphological parameters and the corneal densitometry values.Results: A total of 216 participants were included in this prospective cross-sectional study. The eyes were divided into three groups related to their spherical equivalent (SE) refractive error values as follows: 89 (41.2%) hyperopic eyes, 66 (30.6%) myopic eyes, and 61 (28.2%) emmetropic control eyes. The hyperopic eyes were found to have lower corneal densitometry values in 4 annular zones and the total diameter of all depths except the central layer. However, only the 6-10 mm annular zone of the central and posterior layers of the myopic eyes had lower corneal densitometry values than emmetropic eyes. There was also a significant correlation between spherical equivalence and corneal densitometry values in some zones of the hyperopic eyes. Conclusion: Backward scattering of light was lower in hyperopic eyes and this could affect the visual quality.

scholarly journals Análise do estilo de vida dos profissionais de saúde da oncologia

2018 ◽  
Vol 12 (10) ◽  
pp. 2583
Author(s):  
Isla Naiane Melo Fernandes ◽  
Késia Ribeiro De Almeida ◽  
Fernanda Cardoso Rocha ◽  
Gregório Ribeiro De Andrade Neto ◽  
Mariana De Souza Guedes ◽  
...  
Keyword(s):  
Health Professionals ◽  
Cross Sectional Study ◽  
Significant Variable ◽  
Sectional Study ◽  
Cross Sectional ◽  
Professional Stress ◽  
Lifestyle Questionnaire ◽  
Professional Health ◽  
The Subject ◽  
Quantitative Descriptive

RESUMOObjetivo: analisar o estilo de vida e sua associação com a fadiga por compaixão nos profissionais da saúde. Método: estudo quantitativa, descritivo, transversal, com 22 profissionais do serviço de saúde do setor de oncologia. Utilizou-se para coleta de dados o questionário “Estilo de vida fantástico”, com analise pelo SPSS versão 20.0, apresentadas em tabelas.Resultados: a variável que se obteve com mais significado estatístico neste estudo foi o estilo de vida relacionado à religião dos profissionais onde 76,5% dos participantes classificaram-no como excelente ou muito bom, são católicos e apenas um (20%) participante de outra religião classificou esse estilo como excelente ou muito bom. Conclusão: o profissional de saúde do setor de oncologia percebe seu estilho de vida com qualidade. Ressalta-se a relevância de mais estudos sobre a temática, incorporando a eles práticas efetivas e assertivas para promover a diminuição e/ou extirpação de danos e a criação de políticas que proporcionem melhores condições de trabalho em saúde e valorização dos profissionais de saúde em diversos âmbitos. Descritores: Fadiga por Compaixão; Estilo de Vida; Estresse Profissional; Profissional de Saúde; Serviços de Saúde; Oncologia. ABSTRACTObjective: to analyze lifestyle and its association with compassionate fatigue in health professionals. Method: quantitative, descriptive, cross-sectional study with 22 professionals from the health service of the oncology sector. The "Fantastic Lifestyle" questionnaire was used to collect data, with analysis by SPSS version 20.0, presented in tables. Results: the statistically significant variable in this study was the religion-related lifestyle of professionals where 76.5% of the participants rated it as excellent or very good, are Catholic and only one (20%) participant another religion rated this style as excellent or very good. Conclusion: the health professional of the oncology sector perceives his life style with quality. The importance of further studies on the subject is emphasized, incorporating effective and assertive practices to promote the reduction and / or elimination of damages and the creation of policies that provide better working conditions in health and valuation of health professionals in diverse scopes. Descritores: Compassionate Fatigue; Lifestyle; Professional Stress; Healthcare Professional; Health Services; Oncology. RESUMEN Objetivo: analizar el estilo de vida y su asociación con la fatiga por compasión en los profesionales de la salud. Método: estudio cuantitativo, descriptivo, transversal, con 22 profesionales del servicio de salud del sector de oncología. Se utilizó para recolección de datos el cuestionario "Estilo de vida fantástico", con análisis por SPSS versión 20.0, presentadas en tablas. Resultados: la variable que se obtuvo con más significado estadístico en este estudio fue el estilo de vida relacionado a la religión de los profesionales donde el 76,5% de los participantes lo clasificaron como excelente o muy bueno, son católicos y sólo uno (20%) participante de otra religión que clasificó ese estilo como excelente o muy bueno. Conclusión: el profesional de salud del sector de oncología percibe su estilo de vida con calidad. Se resalta la relevancia de más estudios sobre la temática, incorporando a ellos prácticas efectivas y asertivas para promover la disminución y / o extirpación de daños y la creación de políticas que proporcionen mejores condiciones de trabajo en salud y valorización de los profesionales de salud en diversas áreas. Descritores: Fatiga por Compasión; Estilo de vida; Estrés profesional; Profesional de Salud; Servicios de Salud; Oncología.

scholarly journals EDUCATIONAL TUTORIALS ON THE HOSPITAL PHARMACIST'S RECORD IN THE PATIENT'S MEDICAL RECORDS

2021 ◽  
Vol 21 (44) ◽  
pp. 32-40
Author(s):  
Émilin Dreher De Lima ◽  
Carine Raquel Blatt ◽  
Rita Catalina Aquino Caregnato
Keyword(s):  
Data Collection ◽  
Medical Records ◽  
Online Survey ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Technological Production ◽  
The Subject ◽  
Addie Model ◽  
Two Stages

To document the care on the patient is a necessary skill to the pharmacist. The goal of the study is to prepare educational tutorials related to the registration of Clinical Pharmacy activities in the medical record. It is a technological production carried out in two stages: quantitative cross-sectional study and preparation of educational tutorial videos. Data collection occurred through an online survey of pharmacists active in Brazilian hospitals and Pharmacy professors. The preparation of the educational tutorial videos followed the ADDIE model. 47 professors participated in the research, 100% consider the theme important; and 80% believe that the undergraduate program does not prepare the student for the recording in the medical records. Among the 248 participating pharmacists: only 9% received guidance on the subject during undergraduate course; and less than 40% felt able to record clinical activities in medical records. Three tutorial videos on the recording of the pharmacist's in the medical records were made. The research indicated a need to update the knowledge of Brazilian pharmacists related to the theme record in medical records in services and teaching. The three tutorial videos on the registration of the pharmacist in the medical records were elaborated to disseminate knowledge to pharmacists.

scholarly journals GAMBARAN KELENGKAPAN DAN KESERAGAMAN PENULISAN ODONTOGRAM OLEH DOKTER GIGI DI KOTA SEMARANG

2019 ◽  
Vol 6 ◽  
pp. 40
Author(s):  
Moh. Yusuf ◽  
Syuhada Setiawan ◽  
Andina Rizkia Putri Kusuma
Keyword(s):  
Medical Record ◽  
Study Design ◽  
Treatment Plan ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Subject

Background: Odontogram is one part of the dental record. The odontogram form isfilled with diagnoses and treatment done by the dentist. Odontogram can be used for the further treatment plan and help the forensic department to do the identification. The purpose of this study was to identify the completeness of odontogram filling out by the dentist in Semarang.Method: The research was descriptive using a cross-sectional study design. The subject of the research was graduated dentist in year 2015 until 2017. Subjects were chosen through information from PDGI.Result: The result of this study showed that none of the subjects filled odontogramcompletely, 5 subjects filled less complete and 39 others were categorized incomplete according to medical record guidance book published in 2015.Conclusion: Based on the study, concluded that the need to pay attention aboutthe importance of filling odontogram by the dentist was still low.

scholarly journals Injury characteristics of Indonesian para-athletes prior to Tokyo Olympics 2020: a cross-sectional study

2021 ◽  
Vol 11 (4) ◽  
pp. 679-690
Author(s):  
Yulingga Nanda Hanief ◽  
Prisca Widiawati ◽  
Supriatna Supriatna ◽  
Ahmad Abdullah ◽  
Sri Sumartiningsih
Keyword(s):  
Cross Sectional Study ◽  
The Body ◽  
Sectional Study ◽  
Cross Sectional ◽  
Professional Literature ◽  
National Team ◽  
Injury Management ◽  
Injury Characteristics ◽  
Study Results ◽  
The Subject

BACKGROUND: Sports for people with disabilities and injuries have been the subject of discourse in the professional literature in the fields of traumatology and sports medicine. OBJECTIVE: This research aims to elucidate the injury characteristics of athletes in the Indonesian national team. The subject of this study were nine athletes (male=5, female=4) with males around the age of 28±9.13 and females 28±5.66 years. METHOD: The method approach is descriptive with a cross-sectional study technique using a questionnaire about injury history, types of injury, injury factors, and injury management for Indonesian Para Athletics Athletes who have competed in the 2020 Tokyo Olympics. Data analysis is depicted in numbers and percentages and Fisher's exact test to determine the relationship between variables. RESULTS: The study results reported that Indonesian athletes suffered injuries of the lower limbs (70%), part of the body that is frequently injured was the thigh (28%) and the type of injury that was often experienced sprain/twist. CONCLUSION: The injury characteristics in the sprint (track) category form a pattern of injuries to the thigh, Achilles tendon, ankle, and knee. There appears to be no correlation between gender, training frequency, injury share, match number, and warm-up type. The implication is that injury management is necessary before and during competition by considering biomechanics, pathophysiology, and psychosocial problems. Injury prevention strategies by coaches and medical teams should lead to more significant injury reduction and optimize athletes' health, safety, and well-being.

scholarly journals Biopsychosocial factors and global perceived effect scale on the subject with chronic pain: an analytic cross-sectional study

2020 ◽  
pp. 1-5
Author(s):  
Graziella Cristina Roque ◽  
Tiago Tsunoda del Antonio ◽  
Fabrício José Jassi ◽  
Thais Cristina Chaves
Keyword(s):  
Chronic Pain ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Pain Catastrophizing ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Fear Avoidance Beliefs ◽  
The Subject

Background: Chronic pain is an emotional and sensorial experience that triggers functional incapacity guided especially by the biopsychosocial changes, that lead to its aggravation directly affecting the recovery of the patient. Objective: To verify the presence of biopsychosocial factors in the subject with chronic pain on the physiotherapeutic care undergone in a clinical physiotherapy school. Method: A cross-sectional study, conducted in the physiotherapy clinic of the Health Sciences Center of the Universidade Estadual do Norte do Paraná, in which were evaluated 26 subjects with chronic pain through the Pain Numerical Rating Scale; Hospital Anxiety and Depression Scale; Pain Catastrophizing Scale; Fear Avoidance Beliefs Questionnaire; and Global Perceived Effect Scale. The statistical analysis had significance value of P≤0.05. Results: Even with reduction of pain intensity with P=0.04, the values do not indicate clinically relevant difference. The global perceived effect scale does not indicate a significant improvement of the subjects; however this is justified because the treatment does not address biopsychosocial aspects, being a technical approach. Conclusion: The treatment of chronic pain associated with a biopsychosocial approach would be the most indicated in clinical practice.

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