scholarly journals The Role of Chlorhexidine in the Prevention of Pin Tract Infection as Compared to Povidone-Iodine in Patients Managed by Ilizarov Circular Fixator

2021 ◽  
Vol 15 (5) ◽  
pp. 1751-1754
Author(s):  
Asadullah Makhdoom ◽  
Raheel Akbar Baloch ◽  
Tahir Sheikh ◽  
Jahazaib Khaskhali ◽  
Muhammad Faraz Jokhio ◽  
...  
Keyword(s):  
Tract Infection ◽  
Normal Saline ◽  
Povidone Iodine ◽  
Previous History ◽  
Health Science ◽  
Control Group ◽  
Site Infection ◽  
Pin Site ◽  
The Mean ◽  
Pin Tract Infection

Objective: To compare the efficacy of Chlorhexidine in the prevention of pin tract infection as compared to Povidone-iodine antiseptic. Study Design: Prospective, single blinded randomized trial. Study Setting and Duration: Liaquat University of Health Science (LUMHS), Jamshoro between July 2018 to November 2020. Methodology: All patients who underwent Ilizarov external fixation as per indications were eligible for the study. Individuals with a previous history of osteomyelitis were excluded from the study. Pin sites were cleansed with normal saline using clean applicators. In the group chlorhexidine, the antiseptic was applied on the pin skin interphases (1% chlorhexidine). Similarly, 10% povidone iodine was applied to patients in group C. The control group was cleansed with normal saline. Pin sites were either dressed daily or weekly. The primary outcome was the rate of pin site infection days. Results: Chlorhexidine group had significantly lesser pin-site infections as compared to the povidone-iodine group with a frequency of 13 (39.39%) and 19 (63.33%), p=0.04, respectively. The mean pin tract infection rate days ± SD were significantly lower in the chlorhexidine group as compared to the povidone-iodine group (1.35 ± 2.26 vs 3.54 ± 4.30, p=0.041). Similarly, the mean duration to onset of pin site infection was also significantly higher in the chlorhexidine group compared to povidone-iodine and control groups. Conclusion: Patients who used Chlorhexidine as the cleansing agent had significantly fewer pin-site infections as compared to the povidone-iodine group. Keywords: Chlorhexidine, Ilizarov fixator, fracture, Povidone-iodine

scholarly journals COMPARATION OF EFFECTIVENESS OF NORMAL SALINE AND 10% POVIDONE IODINE IN PERIURETHRAL CLEANING

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Awaluddin Awaluddin
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Normal Saline ◽  
Povidone Iodine ◽  
Urinary Catheter ◽  
Infection Risk ◽  
Control Group ◽  
Tract Infections ◽  
Indwelling Urinary Catheter

Currently, urinary tract infection incidence in patients with indwelling urinary catheter ranges between 10-80%. They are at risk for other problems that can cause death. Appropriate action is required to decrease urinary tract infection risk by periurethral area cleaning. The aim of this study is to analyze the differences of the effectiveness of the use of normal saline and 10% povidone iodine for periurethral area cleaning in decreasing urinary tract infection risk. Research methods uses experimental design with the population of patients who used indwelling urinary catheter. Samples were obtained by consecutive and allocation by randomization which were divided into 2 groups, each group were 17 respondents. In the treatment group, periurethral area was cleaned with normal saline and in the control group with 10% povidone iodine. Urinary tract infection risk assessment was carried out by the leukocyte esterase dipstick test at 8 hours after insertion. The results indicate that the incidence of urinary tract infections risk in the group using normal saline smaller than 10% povidone iodine  with a comparison of 1:1.3. Number need to treat in this study was 6. The conclusion of this study is normal saline is more effective in reducing urinary tract infection risk.

scholarly journals COMPARATION OF EFFECTIVENESS OF NORMAL SALINE AND 10% POVIDONE IODINE IN PERIURETHRAL CLEANING

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Awaluddin Awaluddin
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Normal Saline ◽  
Povidone Iodine ◽  
Urinary Catheter ◽  
Infection Risk ◽  
Control Group ◽  
Tract Infections ◽  
Indwelling Urinary Catheter

Currently, urinary tract infection incidence in patients with indwelling urinary catheter ranges between 10-80%. They are at risk for other problems that can cause death. Appropriate action is required to decrease urinary tract infection risk by periurethral area cleaning. The aim of this study is to analyze the differences of the effectiveness of the use of normal saline and 10% povidone iodine for periurethral area cleaning in decreasing urinary tract infection risk. Research methods uses experimental design with the population of patients who used indwelling urinary catheter. Samples were obtained by consecutive and allocation by randomization which were divided into 2 groups, each group were 17 respondents. In the treatment group, periurethral area was cleaned with normal saline and in the control group with 10% povidone iodine. Urinary tract infection risk assessment was carried out by the leukocyte esterase dipstick test at 8 hours after insertion. The results indicate that the incidence of urinary tract infections risk in the group using normal saline smaller than 10% povidone iodine  with a comparison of 1:1.3. Number need to treat in this study was 6. The conclusion of this study is normal saline is more effective in reducing urinary tract infection risk.

scholarly journals COMPARATIVE STUDY OF PRE-CAESAREAN VAGINAL WASH WITH 5% POVIDONE – IODINE SOLUTION VERSUS NO WASH IN PREVENTING POSTOPERATIVE INFECTION.

2020 ◽  
pp. 44-46
Author(s):  
Sonali Deshpande ◽  
Shrinivas Gadappa ◽  
Dhanashree Lahane ◽  
Sandeep Mannikatti
Keyword(s):  
Surgical Site Infection ◽  
Wound Infection ◽  
Povidone Iodine ◽  
Prophylactic Antibiotic ◽  
Control Group ◽  
Site Infection ◽  
Iodine Solution ◽  
Interventional Group ◽  
Vaginal Wash ◽  
Povidone Iodine Solution

Objective: To evaluate the efficacy of pre-cesarean vaginal wash using 5% Povidone Iodine solution on rate of post-cesarean section (CS) surgical site infection and compared with No swabbing. Method: A Prospective Randomized controlled Trial was conducted in department of Obstetrics and Gynecology in Government medical college, Aurangabad. In interventional group, vaginal swabbing with a gauze pieces impregnated with 5% Povidone Iodine solution was done for 30 seconds. The swabbing of vagina was not performed in cases assigned to control group, however the standard surgical preparation of abdomen was done in a usual manner for both group. All subject received prophylactic antibiotic cover. Collected data was complied in pre-designed proforma and analysis was done using SPSS 15. Result: The risk of post operative fever and wound infection was significantly reduced in interventional group. No measure difference was noted in seroma and composite wound infection. Also less duration of hospital stay in interventional group was noted. No adverse effect of use of Povidone iodine was reported in the interventional group. Conclusion: Vaginal swabbing with 5% Povidone-iodine pre- LSCS is inexpensive and simple intervention even for low resource setting to decrease surgical site infection.

scholarly journals A self-disinfecting irreversible hydrocolloid impression material mixed with povidone iodine powder

2016 ◽  
Vol 10 (04) ◽  
pp. 507-511 ◽  
Author(s):  
Hussien Abdalfatah Ismail ◽  
Hani Asfour ◽  
Souaad Abdulelah Shikho
Keyword(s):  
Dimensional Stability ◽  
Povidone Iodine ◽  
Antimicrobial Effect ◽  
Control Group ◽  
Impression Material ◽  
Irreversible Hydrocolloid ◽  
Weight Test ◽  
The Mean ◽  
And Staphylococcus Aureus ◽  
Stability Results

ABSTRACT Objectives: The aim was to evaluate the effect of adding povidone (PVP) iodine powder with different concentrations to irreversible hydrocolloid on both microbiological and dimensional stability. Materials and Methods: Regular set of (alginate) irreversible hydrocolloid was selected as control group. PVP-iodine powder was mixed with the alginate powder at concentrations of 1, 5, 10, 15, and 20% by weight (test groups). All specimens were tested for their antimicrobial effect against Streptococcus mutans and Staphylococcus aureus as well as dimensional stability. Results: The results of test groups showed that concentrations 1, 5, and 10, weight % had little effect against S. mutans and S. aureus microorganisms. While concentrations 15 and 20 weight % had demonstrated greater effect on microbial growth. The mean of dimensional stability in mm of modified alginate with PVP-iodine at 15 and 20 weight % was –0.119 ± 0.255 and –0.035 ± 0.074, respectively. While the mean dimensional stability in mm of unmodified alginate was –0.112 ± 0.176 . The results of dimensional stability showed that 15 and 20 concentrations of test groups adversely affect the dimensional stability. The adverse effect was noticed to be significant in concentration 20%, where as it was nonsignificant in 15% concentration. Conclusion: Modified alginate impression material with 15 weight % PVP-iodine powered give the material, a self-disinfected properties with less deteriorating effect on dimensional stability.

scholarly journals Postoperative Analgesia for Haemorrhoid Surgery

1983 ◽  
Vol 11 (1) ◽  
pp. 27-30 ◽  
Author(s):  
D. A. Pybus ◽  
B. E. D'Bras ◽  
G. Goulding ◽  
H. Liberman ◽  
T. A. Torda
Keyword(s):  
Postoperative Pain ◽  
General Anaesthesia ◽  
Postoperative Analgesia ◽  
Normal Saline ◽  
Morphine Sulphate ◽  
Control Group ◽  
Treatment Groups ◽  
Number Of Patients ◽  
Caudal Analgesia ◽  
The Mean

Seventy patients undergoing haemorrhoidectomy under general anaesthesia were randomly allocated to one of five treatment groups in order to compare the effectiveness of various caudal agents in the control of postoperative pain. Four groups were given a caudal injection of either 2% lignocaine, 0.5% bupivacaine, 2% lignocaine + morphine sulphate 4 mg or normal saline + morphine sulphate 4 mg, while the fifth (control) group did not receive an injection. The number of patients requiring postoperative opiates was significantly higher in the lignocaine group than in the morphine (p <0.05) and morphine-lignocaine (p <0.05) groups. No agent significantly reduced the number requiring opiates. In those who received opiates, the mean analgesic period was 228 minutes in the control group, and was significantly longer following bupivacaine (577 min, p <0.01), morphine-lignocaine (637 min, p <0.05) and morphine (665 min, p <0.01). The mean analgesic period following lignocaine (349 min) was not significantly different from control. The incidence of catheterisation was lowest in those patients who did not receive caudal analgesia.

Staged distraction osteogenesis followed by arthrodesis using internal fixation as a form of surgical treatment for complex conditions of the ankle

2018 ◽  
Vol 100-B (6) ◽  
pp. 755-760 ◽  
Author(s):  
T-F. Lou ◽  
M. Hamushan ◽  
H. Li ◽  
C-Y. Wang ◽  
Y. Chai ◽  
...  
Keyword(s):  
Tract Infection ◽  
Internal Fixation ◽  
Distraction Osteogenesis ◽  
Wound Dehiscence ◽  
High Rate ◽  
Fixation Index ◽  
Major Complications ◽  
The Mean ◽  
Pin Tract Infection

AimsThe aim of this study was to describe the technique of distraction osteogenesis followed by arthrodesis using internal fixation to manage complex conditions of the ankle, and to present the results of this technique.Patients and MethodsBetween 2008 and 2014, distraction osteogenesis followed by arthrodesis using internal fixation was performed in 12 patients with complex conditions of the ankle due to trauma or infection. There were eight men and four women: their mean age was 35 years (23 to 51) at the time of surgery. Bone healing and functional recovery were evaluated according to the criteria described by Paley. Function was assessed using the ankle-hindfoot scale of the American Orthopedic Foot and Ankle Society (AOFAS).ResultsA solid fusion of the ankle and eradication of infection was achieved in all patients. A mean lengthening of 6.1 cm (2.5 to 14) was achieved at a mean follow-up of 25.2 months (14 to 37). The mean external fixation index (EFI) was 42 days/cm (33.3 to 58). The function was judged to be excellent in six patients and good in six patients. Bone results were graded as excellent in ten patients and good in two patients. The mean AOFAS score was 37.3 (5 to 77) preoperatively and 75.3 (61 to 82) at the final follow-up. Minor complications, which were treated conservatively, included pain, pin-tract infection, loosening of wires, and midfoot stiffness. Major complications, which were treated surgically included grade V pin-tract infection with inflammation and osteolysis, poor consolidation of the regenerate bone, and soft-tissue invagination. The reoperations required to treat the major complications included the exchange of pins and wires, bone grafting and invagination split surgery.ConclusionThe technique of distraction osteogenesis followed by arthrodesis using internal fixation is an effective form of treatment for the management of complex conditions of the ankle. It offers a high rate of union, an opportunity to remove the frame early, and a reduced EFI without infection or wound dehiscence. Cite this article: Bone Joint J 2018;100-B:755–60.

Carbohydrate metabolism in patients with Cushing disease: a glance at the incretin system

2016 ◽  
Vol 62 (5) ◽  
pp. 67-68
Author(s):  
Lubov V. Matchekhina ◽  
Ekaterina A. Shestakova ◽  
Zhanna E. Belaya ◽  
Marina V. Shestakova
Keyword(s):  
Drug Therapy ◽  
Carbohydrate Metabolism ◽  
Previous History ◽  
Pituitary Surgery ◽  
Underlying Disease ◽  
Control Group ◽  
Cushing Disease ◽  
Free Cortisol ◽  
History Of ◽  
The Mean

Introduction. The relevance of carbohydrate metabolism studying in patients with Cushing disease can be explained by frequent occurrence of glucose metabolism disturbances on the one hand, and difficulties in glucose-lowering therapy in these patients on the other. The effectiveness of hyperglycaemia treatment may be reduced due to difficulties in remission / cure of the underlying disease, as well as to the use of specific drug-therapy, leading to the hyperglycaemia. There is a growing interest in research aimed at studying the role of incretin system in the pathogenesis of secondary hyperglycemia associated with neuroendocrine diseases recently.Methods. A total of 20 patients with Cushing disease were included, (19 female and 1 male), the mean age was 37.5 years (18-69). All of the patients were diagnosed with Cushing disease for the first time (using urinary free cortisol levels and MRI-data); none of them had a history of previous drug therapy, radiotherapy or pituitary surgery. The mean HbA1c level was 5,8% (5,3-6,2). All patients underwent OGTT, during which glucose, glucagon, GLP1, GLP2, GIP, ghrelin were measured at 0, 30 and 120 min respectively. The control group included 21 patients without previous history of carbohydrate metabolism disturbances. After OGTT 57% were presented without any carbohydrate metabolism disturbances, 28,57% presented with prediabetes and 14,43% were diagnosed with diabetes.Results. After glucose levels analyzing 40% of patients were diagnosed with early carbohydrate metabolism disturbances ,15% were diagnosed with diabetes. After glucose intake a slight inrease in glucagon levels with a peak by 30’ (p=0,001) compared to gradually decreasing levels in controls was observed . The levels of GIP during OGTT were not significantly different compared to control group. GLP-1 and GLP-2 levels were significantly higher compared to controls (p=0,017 and p<0,001 respectively) with peak levels at 30’. Ghrelin levels were also significantly higher compared to controls (p=0,013)Conclusion. Incretins levels can be possible markers of specific carbohydrate metabolism disturbances in patients with Cushing disease and presumably will help to differentiate steroid diabetes from T2DM. Further investigations needed to prove these speculations.

scholarly journals Effectiveness of periurethral cleaning solution to bacteria colonization count at periurethral area prior to urinary catheterization.

2016 ◽  
Vol 1 (1) ◽  
pp. 66
Author(s):  
Kristina Lisum ◽  
Ni Luh Widani
Keyword(s):  
Patient Safety ◽  
Normal Saline ◽  
Povidone Iodine ◽  
Control Group ◽  
P Value ◽  
Regression Result ◽  
Post Intervention ◽  
Cleaning Solution ◽  
Quasi Experimental ◽  
Reducing Bacteria

<div align='justify> Introduction :Patient safety is an important element that must be notice when providing care to patients, including nurse. The incidence of catheterized patient increasingly 25 % from total patients that hospitalized can lead urinary tract infection.  The purpose of this study was to compare the effectiveness of cleaning periurethral with povidone iodine 10 %, povidone iodine 2 % and normal saline to bacteria colonization prior to catetherization. Methods : This study used quasi-experimental, pre and post intervention design with control group.  Result : Periurethral swabs were obtained from a total 60 patients ( povidone iodine 10 % as control group , 20;  povidone iodine 2 %, 20; normal saline, 20).  Through paired t-test ,there  was significant decreased  (p value : .00; p < .05) in bacteria colonization count  using povidone iodine 2% and normal saline ; using  povidone iodine  10 %  , there was no significant decreased (p value : .55; p >.05) in bacteria colonization count. While, a simple linear regression result that povidone iodine 2% is the most effective solution on reducing bacteria colonization in periurethral area rather than other solution. In addition, recommendation needed to test bacteria colonization in urine culture using those periuretral cleaning solutions. Keyword: periurethral cleaning, patient safety, povidone iodine 2%, povidone iodine 10%, normal saline

scholarly journals Static monolateral external fixation for the Rolando fracture: a simple solution for a complex fracture

2012 ◽  
Vol 94 (2) ◽  
pp. 112-115 ◽  
Author(s):  
D Marsland ◽  
AP Sanghrajka ◽  
B Goldie
Keyword(s):  
External Fixation ◽  
External Fixator ◽  
Case Series ◽  
X Rays ◽  
Site Infection ◽  
Study Support ◽  
Pin Site ◽  
The Mean ◽  
Joint Incongruity ◽  
Mean Time

INTRODUCTION Rolando fractures are often difficult to manage because of their inherent instability. We describe a simple technique for the treatment of this fracture using the principle of ligamentotaxis, with a static, two-pin external fixator spanning the trapeziometacarpal joint, and present the results of a single-surgeon case series. METHODS Eight consecutive patients (mean age: 32.8 years) with Rolando fractures were treated using a Hoffmann II® Micro small bone external fixator using blunt ended 2.0mm half pins, inserted into the trapezium and diaphysis of the first metacarpal. Functional outcome was assessed with the Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) score at a mean time of 2.7 years following the fracture (range: 4 months – 6.0 years). The mean time to frame removal was 28 days. RESULTS There were three cases of superficial pin site infection. Follow-up x-rays at four months did not demonstrate significant joint incongruity or malunion in any case. The mean QuickDASH score was 7.95 and all patients returned to their previous levels of activity. CONCLUSIONS Although external fixation risks pin site infection, the results of this study support the use of spanning trapeziometacarpal external fixation for Rolando fractures as it reliably gives excellent functional outcomes.

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