scholarly journals A Study on Serum Uric Acid Level in Type II Diabetes Mellitus

2021 ◽  
Vol 15 (7) ◽  
pp. 2317-2319
Author(s):  
Kashif Ali Samin ◽  
Khalil Ullah ◽  
Muhammad Ikram Shah ◽  
Abidamateen Ansari ◽  
Sadia Khalil ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Type Ii Diabetes ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Type Ii Diabetes Mellitus ◽  
Diabetic Patients ◽  
Type Ii

Background and Aim: Morbidity and mortality from non-communicable diseases, particularly diabetes are increasing rapidly in Pakistan, the prevalence has reached 17.1%. A strong association has been witnessed between type II diabetes mellitus with atherosclerosis and serum uric acid level. The current study aim was to assess the levels of serum uric acid in type II diabetes mellitus. Materials and Methods: This cross-sectional study was carried out on 85 diagnosed patients of type II diabetes mellitus in Diabetes hospital, Peshawar and the Department of General Medicine, Shaikh Zayed Medical Complex, Lahore during the period from March 2020 to August 2020.Type II diabetes mellitus (DM) diagnosed patients 85 and healthy control 30 were evaluated in this study. The level of hyperuricemia was defined for women > 6 mg/dl and men >7 mg/dl in men. Results: In this study, a total of 85 diabetic diagnosed patients and 30 healthy controls were enrolled. No significant differences were there in the baseline characteristics like anthropometric and socio-demographic parameters. The mean age for diagnosed and control cases was 58.6±8.7 and 56.5±7.6 years with an age range of 40 and 80 years. Hyperuricemia proportion among diabetic patients was 12.13% while none of the control cases had hyperuricemia. The uric acid means level increased from 4.29±0.81 mg/dl with a diabetic duration between 3 and 4 years to 4.59±0.99 mg/dl with a diabetic duration of 5 to 7 years. Furthermore, mean serum uric acid level reached 6.50±1.08 in cases with diabetic duration 8 to 12 years. Statistically, a significant association was found between diabetic duration and serum uric acid. Also, a positive correlation was found in hyperlipidemia, serum uric acid levels, and hypertension. Conclusion: In diabetic patients serum uric acid levels were found to be significantly higher. Diabetic patients had hypertension, elevated serum uric acid levels, and high triglycerides with dyslipidemia. The rise in serum uric acid levels is proportional to the duration of diabetes. Keywords: Serum uric acid, Type 2 diabetes mellitus, Hypertension

scholarly journals Elevated serum uric acid and triglycerides level in the patients with Type II Diabetes Mellitus- a Nepalese case control study

2017 ◽  
Vol 2 (2) ◽  
pp. 26-34
Author(s):  
Hridaya Parajuli ◽  
Jyotsna Shakya ◽  
Bashu Dev Pardhe ◽  
Puspa Raj Khanal ◽  
Narayan Prasad Parajuli ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Diabetic Patients ◽  
Type Ii ◽  
Significant Difference

Background: Hyperuricemia is associated with type 2 diabetes, which is a metabolic disorder of multiple etiologies resulting from defects in insulin action. The present study wascarried out to look for any association between uric acid and Type II Diabetes Mellitus and also status of triacylglycerol level among those patients.Methods: The blood samples were collected 100 diabetic and 100 non-diabetic individuals in the department of biochemistry and then analyzed for estimation of blood glucose, Uric Acid and Triacylglycerol level.Results: The average level of serum uric acid in diabetic patients was higher (5.706±1.617) in comparison to non diabetic subjects (4.322±0.784) with statistically significant difference (p≤0.05). For female the result indicate there was a positive correlation between (FBS and triglycerides) and (triglycerides and uric acids) which was statistically significant (r =-0.465, n = 41, p = 0.002) and(r =-0.370, n = 41, p = 0.017) respectively.Conclusions: This study documents that hyperuricemia is associated with type 2 diabetes mellitus. Furthermore, the serum triacylglycerol and serum uric acid is also found to be associated risk factors for diabetic complications. Hence, timely diagnosis and management of diabetes is vital to control the complications related to diabetes.Ann. Clin. Chem. Lab. Med. 2016:2(1); 26-34

scholarly journals Serum uric acid level is associated with type 2 diabetes mellitus and diabetic regulation

2018 ◽  
Vol 1 (4) ◽  
pp. 134-138 ◽  
Author(s):  
Burcin Meryem Atak ◽  
Tuba Taslamacioglu Duman ◽  
Mehmet Zahid Kocak ◽  
Haluk Savli
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level

scholarly journals Serum uric acid level in type 2 diabetes mellitus

2019 ◽  
Vol 6 (4) ◽  
pp. 1265
Author(s):  
D. Vasantha Kalyani ◽  
M. Ilamaran ◽  
P. Suresh Kumar ◽  
Saranya Nagalingam
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
The Mean ◽  
Artery Disease

Background: Diabetes mellitus is the most important risk factor associated with two to four fold increased incidence of coronary artery disease. The major risk factors for CAD are hypercholesterolemia, hypertension, diabetes mellitus, and cigarette smoking Objectives: To study the level of serum uric acid in type 2 diabetes mellitus and the correlation between elevated serum uric acid level and the component of metabolic syndrome like obesity, hypertension, dyslipidemia.Methods: The study was done as descriptive analytical study among the diabetic patients in a tertiary care setting during the period January 2018 to February 2019. The inclusion and exclusion criteria were clearly defined and the study participants were recruited for the study after getting the informed consent. The socio demographic profile, clinical and laboratory data were collected from the blood sample obtained from the patients with the standardized procedures. Data was entered in Microsoft excel spread sheet and analyzed statistically using SPSS statistical software. Student ‘t’ test and Chi-square test values were applied for significance.Results: Serum uric acid in the study population and control varied from 3.0 to 8.1 and 2.7 to 5.5 mg/dl respectively. The mean and standard deviation of uric acid among cases was 5.08±1.42 while in control it was 3.55±0.62 respectively. The serum uric acid level of diabetics was very much elevated compare with controls and it was highly significant. Significant correlation was noticed between serum uric acid and BMI as well as WHR. Elevated uric acid levels were significantly noticed among those with hypertension, dyslipidemia, coronary artery disease and chronicity of the diabetes.Conclusions: Uric acid was significantly elevated in diabetic population and the mean value of serum uric acid level was higher in longer duration of diabetes, hypertension, dyslipidemia, central obesity which are the components of metabolic syndrome.

scholarly journals STUDY OF SERUM URIC ACID LEVEL IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

2021 ◽  
pp. 36-38
Author(s):  
Rohit Mathew ◽  
Aswathy Joseph
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Life Style Changes

BACKGROUND:Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. AIM:To evaluate the serum uric acid level in patients with type 2 Diabetes mellitus. MATERIALS AND METHODS:It was a prospective observational study conducted on 100 patients attending Medicine Department of Jhalawar Medical College, Jhalawar, Rajasthan. The study was done to assess the uric acid status in patients with diabetes mellitus and to find out its association with Age, Gender, Body Mass Index (BMI), Waist Hip Ratio (WHR), Dyslipidemia and Hypertension. Relevant history, vitals, clinical examination and laboratory investigations were done and recorded. RESULTS:This study evaluated the level of serum uric acid in Type 2 diabetes mellitus patients and confirmed there significantly high prevalence of hyperuricemia among type 2 diabetes subjects and increased association with increasing age, BMI, WHR, Dyslipidemia, Hypertension and female sex. CONCLUSION: Patients with Poor metabolic control and longer duration of diabetes were more susceptible to develop various complications including hyperuricemia. Early diagnosis and control of Diabetes Mellitus and its complications is indicated and potential therapeutic approaches (therapeutic life style changes and pharmacotherapy) should be initiated.

CORRELATION OF SERUM URIC ACID LEVEL WITH GLYCAEMIC STATUS IN TYPE 2 DIABETES MELLITUS PATIENTS IN DARBHANGA

2021 ◽  
pp. 68-70
Author(s):  
Mritunjay Kumar ◽  
Sheela Kumari ◽  
Debarshi Jana
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Blood Glucose ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level

Objectives : Our study was to detect the correlation of serum uric acid level with glycaemic status and with lipid prole. And also evaluate the various biochemical parameters, anthropometric measurements, blood pressure, serum uric acid level and associated factors. Methods: A 100 subjects with type 2 diabetes mellitus as a case and 100 subjects with non diabetics as control with age group greater than 40 years were enrolled in this study. A detail history, dietary pattern, clinical examination and relevant investigation were performed. Anthropometric examination like as measurement of BMI, measurement of waist-hip ratio and biochemical investigations like as blood glucose, serum HbA1c estimation, serum uric acid and serum lipid prole were performed to all subjects. Results : Data was analyzed by using SPSS software. Mean±SD was observed. P value was taken ≤0.05 for signicant differences. Conclusion : Type 2 diabetes mellitus patients is a strong negative correlation between blood glucose level and serum uric acid level. So that serum uric acid can be used as an important parameter to assess future cardiovascular risk in a type 2 diabetes mellitus patient.

MS493 EFFECT OF LOVASTATIN THERAPY AND WITHDRAWAL ON SERUM URIC ACID LEVEL IN TYPE II DIABETIC NEPHROPATHY

2010 ◽  
Vol 11 (2) ◽  
pp. 209
Author(s):  
N. Nezami ◽  
J. Safa ◽  
H. Argani ◽  
A. Ghorbanihaghjo ◽  
A.M. Vatankhah
Keyword(s):  
Uric Acid ◽  
Diabetic Nephropathy ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Type Ii
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