Biochemical Markers of Ovarian Reserve in Females, Effect of Exercise on Such Reserves

2021 ◽  
Vol 15 (8) ◽  
pp. 2260-2262
Author(s):  
Ayesha Zubair ◽  
Anas Khalil ◽  
Hassan Jamil ◽  
Anam Rehman ◽  
Bashir Ahmed Shaheen ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Aerobic Exercise ◽  
Ovarian Reserve ◽  
Biochemical Markers ◽  
Exercise Group ◽  
Slight Reduction ◽  
Heavy Exercise ◽  
Exercise Tests ◽  
Significant Difference ◽  
Sedentary Life

Background: Female who are in fertile period of their life and prefer a sedentary life style rather than performing regular physical exercise, whether light or heavy exercise show different hormonal pattern which effect their physical health. Such hormonal changes are directly related to the level of ovarian reserve of hormones which are negatively affected by lack of exercise. The ovarian pool of hormones decline with age and also lack of physical exercise. Among the large pool of biochemical markers AMH (anti-mullerian hormone) appears to be the most important and helpful indicator of ovarian reserve. Inclusion criteria: Healthy females between 25 to 35 years of age were included in the study. Exclusion criteria: Females below 25 years and above 35 years of age were excluded from the study, in addition those females having some medical problem or using some medication were also excluded from the study. Material and Methods: 20 females consented to participate in the study who were divided in two groups. These females were living a sedentary life before they joined the gymnasium. One group was subjected to light aerobic exercise and other group to heavy physical exercise. Tests before the start of study were conducted and were repeated after 08 weeks of study to observe the effect of both exercises on the ovarian reserves of different hormones. Results: The comparison between both groups were observed, the values before and after exercise has a remarkable difference, a decrease in values were observed in body weight, BMI, waist and hip ratio after exercise. Slight reduction in E2 and FSH level after aerobic exercises was observed. Whereas in heavy exercise group significant difference i.e. increase in level of FSH was observed at the same time, significant decrease in AMH level was also observed. The difference between E2 and LH had no significance in heavy exercise group. Conclusion: Those females who were living sedentary life and performed light aerobic exercise, even for a longer time period did not showed significant change in the E2, LH, FSH and AMH level of hormones. However, heavy exercise reduces the level of AMH and increases the level of FSH. These finding suggest heavy exercise may affect fertility in a negative way especially in females with low ovarian reserves. Keywords: Exercise, spinning, ovarian reserve, AMHh anti-mullerian hormone

scholarly journals β-endorphin response to aerobic and anaerobic exercises in Wistar male rats

2020 ◽  
Vol 29 (3) ◽  
pp. 245-9
Author(s):  
Rostika Flora ◽  
Mohammad Zulkarnain ◽  
Sukirno
Keyword(s):  
Physical Exercise ◽  
Aerobic Exercise ◽  
Brain Tissue ◽  
Exercise Group ◽  
Anaerobic Exercise ◽  
Treadmill Running ◽  
Male Rats ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Aerobic And Anaerobic

BACKGROUND Physical exercise is strongly associated with the release of β-endorphin. It is assumed that the type and intensity of physical exercise contributes to the release of β-endorphin. This study aimed to compare levels of β-endorphin in brain tissue in response to aerobic and anaerobic physical exercise. METHODS This study was an experimental laboratory study using 35 male Wistar rats divided into one control group and two physical exercise treatment groups: aerobic and anaerobic. Physical exercise was conducted on an animal treadmill running at aspeed of 20 m/min for 30 min of aerobic exercise and 35 m/min with 1-min intervals every 5 min for 20 min for anaerobic exercises. Each aerobic and anaerobic exercise group was furtherly classified into three subgroups (1×/week, 3×/week, and 7×/week). β-endorphin levels were determined using enzyme-linked immunosorbent assay. The data were analyzed using independent t-test and one-way analysis of variance. RESULTS The highest mean of β-endorphin level was found in the weekly exercise (54.45 [1.41] pg/ml) of aerobic exercise group and daily exercise (70.50 [11.67] pg/ml) of anaerobic exercise group. Mean of β-endorphin level in control group was 33.34 (3.54) pg/ml. A significant increased of β-endorphin mean level (p<0.001) was found in all aerobic and anaerobic exercise groups except the aerobic exercise 7×/week group(37.37 [6.30] pg/ml) compared to control. CONCLUSIONS Both aerobic and anaerobic physical exercise conducted for 6 weeks could increase the level of β-endorphin in brain tissue.

Grape juice and aerobic exercise on blood pressure

2019 ◽  
Vol 50 (5) ◽  
pp. 987-998 ◽  
Author(s):  
Juliane Barroso Leal ◽  
Juçara Barroso Leal ◽  
Joaline Barroso Portela Leal ◽  
Yan de Lima Borges ◽  
Maria Ivone Leal de Moura ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Physical Exercise ◽  
Aerobic Exercise ◽  
Diastolic Pressure ◽  
Systolic Pressure ◽  
Grape Juice ◽  
Exercise Group ◽  
Control Group ◽  
Content Type ◽  
Before And After

Purpose This paper aims to verify the effect of 12 weeks of grape juice (GJ) consumption associated with aerobic exercise on the variation of the hypertensive elderly pressure. Design/methodology/approach A total of 45 hypertensive elderly of both sexes were distributed into: control group (CG, n = 10), exercise group (EG, n = 10), juice group (JG, n = 12) and juice and exercise group (JEG, n = 13). Blood pressure and heart rate were checked weekly before exercise in JG and JEG, and before and after intervention in all groups, with JG and JEG supplemented with 200 mL of GJ. Three weekly sessions of moderate walking were applied. Findings There was a reduction in EG, JG and JEG for systolic pressure and diastolic only for JG and JEG. The GJ consumption to the practice of aerobic exercise provided reductions in the arterial pressure of hypertensive, in addition to stabilization of the diastolic pressure. Research limitations/implications Although the objective of the study was to compare the effect and value of intervention with controls, the study had no intervention in food consumption, which could have led to more significant results. There was a limitation in the control drink, leading the study not to be blind, which may have impaired the results. However, it is probably not a bias, as the groups were divided by residence area, and therefore, had no direct contact with the other groups. Another limitation was that the sample size was still small, which would lead to more reliable results. Finally, although the existing limitations cannot be disregarded, the results of this research are very promising, especially when the objective is the effect of GJ and aerobic exercise on blood pressure, with the possibility of implementing supplemental GJ and the inclusion or not of exercise to the hypertensive elderly. Originality/value The paper deals with the benefits of GJ consumption associated with aerobic physical exercise on the blood pressure of elderly hypertensive patients. Considering that GJ along with physical exercise was enough to reduce the blood pressure of hypertensive elderly, this may be a new model to be used to reduce and/or control blood pressure, and GJ and the exercise to be part of the daily life of the population.

scholarly journals Cardiovascular Responses Of Type 2 Diabetes Patients To Intermittent And Continous Aerobic Exercises

2007 ◽  
Author(s):  
Mukadas O Akindele ◽  
Phillip Kodzo ◽  
Mustapha Naimat
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Aerobic Exercise ◽  
Intermittent Exercise ◽  
Cardiovascular Responses ◽  
Exercise Group ◽  
Significant Difference

Background: The use of aerobic exercise as a form of glycemic control in type 2 diabetes mellitus has been well documented in the literatures. High blood pressure has been shown to be one of the sequelae of type 2 diabetes mellitus. Determination of mode of exercises for glycemic control that will not adversely affect the cardiovascular indices of type 2 diabetes mellitus subjects is highly indicated. Objective: The purpose of this study was to determine the acute cardiovascular responses of type 2 diabetes mellitus subjects to continuous and intermittent modes of exercises. Results: There was statistical significant difference in heart rate of both groups. Continuous mode of exercise elicited no statistical difference in SBP and DBP but there was statistical significant difference in SBP in intermittent exercise group with no statistical significant in their DBP. Cross comparison of pre and post cardiovascular indices showed that there were statistical significant differences in SBP (F=0.710, P>0.05) and DBP (F=1.397, P>0.05). Conclusion: Cardiovascular responses of type 2 diabetes mellitus subjects were higher in intermittent exercise group compared with the continuous exercise group. KEYWORDS: Type 2 diabetes mellitus, Aerobic exercise, cardiovascular response.

scholarly journals PO-285 A review of effects of exercise on the quality of life in breast cancer survivors

2018 ◽  
Vol 1 (5) ◽  
Author(s):  
Feng Hong
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Physical Exercise ◽  
Cancer Survivors ◽  
Aerobic Exercise ◽  
Breast Cancer Survivors ◽  
Exercise Group ◽  
Control Group ◽  
Supervised Exercise

Objective Breast cancer is one of the most common malignant tumors in women.The number of women diagnosed with breast cancer each year is also increasing.It is also the leading cause of cancer deaths in women, accounting for 14-23% of cancer deaths.However, with the development of medical technology, the survival rate of breast cancer patients is improving.In general, the treatment of breast cancer mainly includes surgical treatment, adjuvant chemotherapy and radiotherapy，But these treatments can do a lot of damage to breast cancer patients.These injuries can limit some of the physical activity of breast cancer patients, and can be accompanied by significant psychological damage，Therefore, the quality of life of breast survivors is largely destroyed.Physical exercise is one of the important ways to improve the overall health of the human body.It also plays an important role in increasing people's mood and quality of life.So whether physical exercise has a positive impact on improving the quality of life of breast cancer survivors or there is some doubt.Therefore, the main purpose of this study is to explore the impact of physical exercise on the quality of life of breast cancer survivors, and then to prove the impact of supervised exercise and individual exercise on the quality of life of breast cancer survivors. Methods Data bases searched were MEDLINE, EMBASE, CINAHL, PubMed.Keywords were“breast cancer and quality of life” in combination with “exercise”or “physical activity”.At the same time, the references of the included articles were reviewed to obtain more relevant studies.In terms of the criteria for inclusion and exclusion of literature, the paper was initially screened to determine whether the title and abstract of the paper were consistent with the research topic.The criteria for inclusion are ①the subjects were breast cancer survivors,②the type of intervention was physical exercise,③the measured result is quality of life,④the type of experiment is randomized controlled trial.The exclusion criteria of the article are ①the subject's occupation was athlete，②quality of life is not measured on a formal scale，③article type is review or abstract. Results A total of 14 articles are included in our review.Quality of life was measured using scale tools in all included studies, of which two scales were used in all included articles.The two scales used can reflect the real life quality of the subjects, of which FACT-G is a mass life quality scale and FACT-B is a life quality scale designed specifically for breast cancer patients. Both scales are globally recognized by the public.In our review, we found that exercise significantly improved the quality of life of breast cancer survivors, particularly aerobic exercise.In the studies included in our study, except Nanette et al. used aerobic exercise combined with resistance strength training as the intervention method in their study, all the other studies used aerobic exercise as the intervention method for the subjects.Among the 14 included studies, 10 indicated that physical exercise significantly increased the quality of life of breast cancer survivors, and 4 found that compared with the control group, the quality of life of breast cancer survivors did not have significant changes, but there was a trend of improving the quality of life.At the same time, our review found that monitoring breast cancer survivors improved quality of life.In two of the studies we included, subjects were divided into individual exercise groups and supervised exercise groups.In their study, Anne et al. divided the recruited research samples into the supervision intervention group and the routine control group. Among them, the supervision intervention group received physical exercise 5 times a week for 12 weeks, and the quality of life of breast cancer survivors was significantly improved.In the study of Cadmus et al., the subjects recruited were divided into individual exercise group, supervised exercise group and routine control group, and the exercise group performed physical exercise with the same load and frequency. The result was that there was no physical activity in the home individual exercise group or the routine control group that improved the quality of life for breast cancer survivors.However, in the supervised exercise group, breast cancer survivors' scores for FACT-B and SF-36 (a measure reflecting quality of life) were significantly improved. Conclusions Exercise can improve the quality of life for breast cancer survivors, especially aerobic exercise. Supervised exercise intervention for breast cancer survivors can better improve their quality of life and alleviate social and psychological problems than individual exercise.The supervised aerobic exercise can be integrated into the life of breast cancer survivors so as to better promote the recovery of breast cancer survivors.

scholarly journals Effects of different exercise loads on serum betatrophin (ANGPTL-8/lipasin) and cartonectin (CTRP-3) levels in metabolic syndrome

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Muhammed Emre Karaman ◽  
Cengiz Arslan ◽  
Mehmet Ferit Gürsu
Keyword(s):  
Metabolic Syndrome ◽  
Aerobic Exercise ◽  
Tap Water ◽  
Exercise Group ◽  
Anaerobic Exercise ◽  
Male Rats ◽  
Control Group ◽  
Standard Diet ◽  
Positive Effects ◽  
Significant Difference

Abstract Objectives The number of studies examining the circulating level change of betatrophin and cartonectin in metabolic syndrome applying different loads of exercise is limited. The purpose of the present study was to investigate how different loads of exercises regulate the betatrophin and cartonectin levels in metabolic syndrome induced rats. Methods A total of 24 Wistar-Albino male rats were used in the study. Rats were divided into four groups as follows; G1: control group (fed with standard diet and tap water), G2: metabolic syndrome group (without exercise application), G3: metabolic syndrome + aerobic exercise group (aerobic exercise applied), G4: metabolic syndrome + anaerobic exercise group (anaerobic exercise applied). Betatrophin and Cartonectin levels were determined by ELISA method in serum samples. Results There was a statistically significant difference in betatrophin levels between the groups and this differentiation was caused by G2 (p <0.05). Cartonectin levels were not significantly different between groups (p> 0.05). Conclusions It can be concluded that anaerobic exercises have more positive effects on glucose balance in metabolic syndrome than aerobic exercises, and by regulating betatrophin levels, anaerobic exercises indicate this effect.

scholarly journals Assessment of Propolis Supplementation on Serum Concentrations of Liver Enzymes in Endurance Athletes with Four Weeks Aerobic Training

2021 ◽  
Vol 25 (1) ◽  
pp. 25-30
Author(s):  
Mojtaba Mahdavi Asiabar ◽  
◽  
Mokhtar Nasiri Farsani ◽  
Nematollah Gheibi ◽  
◽  
...  
Keyword(s):  
Aerobic Exercise ◽  
Aerobic Training ◽  
Liver Enzymes ◽  
Cell Function ◽  
Serum Levels ◽  
Exercise Group ◽  
Cellular Level ◽  
Endurance Athletes ◽  
Serum Concentrations ◽  
Significant Difference

Background: Aerobic and intense exercises with an increase in free radicals cause damages at the cellular level, heart disease, cancer, and the development of aging processes, which one of its symptoms is increased serum concentrations of liver enzymes. Objective: The purpose of this study was to investigate the concurrent effect of four weeks of aerobic training and propolis supplementation on the activity of liver enzymes, including ALT, AST, and SOD in endurance athletes. Methods: Thirty-two male athletes (age: 21±1.4 years) in track and field were randomly divided into three groups: exercise group, exercise with placebo group, and exercise with supplement group. Propolis supplementation was taken as two tablets (500 mg) twice a day and aerobic exercise was performed for 4 weeks and in 24 sessions with an intensity of 60 to 65% of heart rate. The statistical method was done using one-way ANOVA and Tukey post hoc test by SPSS v. 18 software. Findings: The results showed that there was a statistically significant difference between groups in serum levels of SOD, AST, and ALT (P<0.05). There was not a statistically significant difference between the exercise group and placebo+exercise group in serum levels of SOD, AST, and ALT (P>0.05). Conclusion: The results showed that aerobic exercise alone can increase SOD levels and propolis supplementation with aerobic exercise can reduce AST and ALT serum levels and lead to improved liver cell function.

scholarly journals Evaluation of oxidative stress in mice subjected to aerobic exercise

2012 ◽  
Vol 27 (8) ◽  
pp. 544-551 ◽  
Author(s):  
Mônica Cruvinel de Lima ◽  
Guido Marks ◽  
Iandara Schettert Silva ◽  
Baldomero Antonio Kato da Silva ◽  
Lourdes Zélia Zanoni Cônsolo ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Smooth Muscle ◽  
Aerobic Exercise ◽  
Striated Muscle ◽  
Exercise Program ◽  
Exercise Group ◽  
Control Group ◽  
Adaptation Period ◽  
Intergroup Comparison ◽  
Significant Difference

PURPOSE: To evaluate the influence of aerobic exercise on oxidative stress in mice. METHODS: The study included twenty female mice Mus musculus-Swiss divided into two groups: sedentary control (GA) and exercise (GB), each containing ten animals. All animals underwent an adaptation period of seven days isolated in individual boxes. After this period, the animals in the exercise group (GB) were trained in angled running wheel with circumference of 25 cm assembled on an articulated axle during five minutes for three consecutive days. On the fourth day, they underwent an exercise program of one session lasting 45 minutes. The evaluation of oxidative stress was performed by determining the levels of malondialhyde derived of lipid peroxidation by the TBA method. The samples were read in a spectrophotometer at 535 nm. RESULTS: No significant difference was observed in the intergroup comparison of MDA levels in the tissues evaluated. A significant difference was observed in the intragroup comparison of MDA levels in the control group (p = 0.0201).The Tukeys' post hoc test indicated significantly lower values of MDA in the smooth muscle in relation to plasma. In the analysis of variance in the exercise group, a significant difference between tissues (p = 0.0009), with significantly lower values in the smooth muscle in relation to plasma (p<0.001) and higher in striated muscle in relation to smooth muscle (p<0.05) was observed. CONCLUSION: There was no change in the analysis of oxidative stress in mice which were undergone a single session of aerobic exercise.

Regular Physical Exercise Improves Physical Motor Functions and Biochemical Markers in Middle-Age and Elderly Women

2009 ◽  
Vol 6 (1) ◽  
pp. 55-62 ◽  
Author(s):  
Takashi Kamijo ◽  
Masami Murakami
Keyword(s):  
Physical Exercise ◽  
Biochemical Markers ◽  
Elderly Women ◽  
Middle Age ◽  
Exercise Group ◽  
Control Group ◽  
Model Assessment ◽  
Motor Functions ◽  
Lifestyle Related Diseases ◽  
Regular Physical Exercise

Background:Lifestyle-related diseases among middle-age and elderly people have become serious problems. Underlying causes might be related to the changes in the lifestyle including the absence of regular physical exercise.Methods:To clarify the significance of regular physical exercise to prevent lifestyle-related diseases, we studied motor functions and blood chemistry examinations in middle-age and elderly women (over 40 years old) who performed regular physical exercise for 2 years (exercise group) and those who initially did not (control group).Results:In study 1, VO2max significantly increased in the exercise group compared with the control group in the under 60 years old groups. In the over 60 years old groups, VO2max, foot balance, and HDL-cholesterol significantly increased. Plasma glucose at 120 minutes after the 75 g oral glucose tolerance test, fasting insulin, homeostasis model assessment (HOMA-R), and high sensitivity C-reactive protein (hsCRP) significantly decreased in the exercise group compared with the control group. In study 2, a 1-year exercise program significantly improved physical functions and biochemical markers in the control group.Conclusion:These results suggest that regular physical exercise might help to maintain sound motor functions and decrease insulin resistance and a risk for arteriosclerosis.

Effect of Physical Exercise Prelabyrinthectomy on Locomotor Balance Compensation in the Squirrel Monkey

1989 ◽  
Vol 68 (2) ◽  
pp. 407-414 ◽  
Author(s):  
Makoto Igarashi ◽  
Kazuhiro Ohashi ◽  
Toshio Yoshihara ◽  
Scott Macdonald
Keyword(s):  
Physical Exercise ◽  
Squirrel Monkey ◽  
Maintenance Phase ◽  
Exercise Group ◽  
Squirrel Monkeys ◽  
Control Group ◽  
Balance Function ◽  
Significant Difference ◽  
Unilateral Labyrinthectomy ◽  
Experimental Group

This study examines the effectiveness of physical exercise, during a prepathology state, on locomotor balance compensation after subsequent unilateral labyrinthectomy in squirrel monkeys. An experimental group underwent 3 hr. of daily running exercise on a treadmill for 3 mo. prior to the surgery, whereas a control group was not exercised. Postoperatively, the locomotor balance function of both groups was tested for 3 mo. There was no significant difference in gait deviation counts in the acute phase of compensation. However, in the chronic compensation maintenance phase, the number of gait deviation counts was fewer in the exercise group, which showed significantly better performance stability.

scholarly journals P.134 Movement medicine: A systematic review on the effect of early aerobic exercise initiation on symptom recovery following concussion

2021 ◽  
Vol 48 (s3) ◽  
pp. S58-S58
Author(s):  
A Kempenaar ◽  
M Bayley
Keyword(s):  
Aerobic Exercise ◽  
Early Period ◽  
Exercise Group ◽  
Initial Symptom ◽  
Brain Concussion ◽  
Early Exercise ◽  
Post Concussion Syndrome ◽  
Significant Difference ◽  
Promising Treatment ◽  
Symptom Recovery

Background: Mounting evidence supports aerobic exercise as a promising treatment option for individuals experiencing persistent post-concussion symptoms beyond four weeks. The purpose of this review was to determine whether initiating structured aerobic exercise within the early period (first two weeks) following concussion affects symptom recovery compared to standard care. Methods: A systematic literature search was performed using MEDLINE, Embase, PsycINFO and CENTRAL databases, combining keywords: (brain concussion, post-concussion syndrome, mild traumatic brain injury) AND (exercise, exercise therapy, physical activity, kinesiotherapy). Results were limited to Randomized Controlled Trials (RCTs). All selected articles underwent quality assessment. Results: The search generated 112 unique abstracts, of which 5 met inclusion criteria. Sample sizes ranged from 16 to 103 participants. Of the four studies that were able to analyze between-group differences, one showed significantly faster recovery in the early aerobic exercise group compared to control, while three showed no significant difference. Two studies demonstrated a trend toward faster initial symptom resolution in the early exercise group. Conclusions: Preliminary RCT evidence suggests that aerobic exercise initiated in the early postconcussion period does not exacerbate symptoms or prolong recovery time, and may potentially hasten recovery. Larger, more rigorous RCTs are required to define the optimal exercise parameters to facilitate symptom recovery.

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