Targeted Muscle Reinnervation and its Role in Acute Management of Above-Elbow Amputations

2017 ◽  
Vol 25 (9) ◽  
pp. 664
Author(s):  
Mark A. Tait ◽  
John W. Bracey ◽  
Bryan J. Loeffler ◽  
Raymond G. Gaston
Hand ◽  
2021 ◽  
pp. 155894472199246
Author(s):  
David D. Rivedal ◽  
Meng Guo ◽  
James Sanger ◽  
Aaron Morgan

Targeted muscle reinnervation (TMR) has been shown to improve phantom and neuropathic pain in both the acute and chronic amputee population. Through rerouting of major peripheral nerves into a newly denervated muscle, TMR harnesses the plasticity of the brain, helping to revert the sensory cortex back toward the preinsult state, effectively reducing pain. We highlight a unique case of an above-elbow amputee for sarcoma who was initially treated with successful transhumeral TMR. Following inadvertent nerve biopsy of a TMR coaptation site, his pain returned, and he was unable to don his prosthetic. Revision of his TMR to a more proximal level was performed, providing improved pain and function of the amputated arm. This is the first report to highlight the concept of secondary neuroplasticity and successful proximal TMR revision in the setting of multiple insults to the same extremity.


Hand Clinics ◽  
2021 ◽  
Vol 37 (3) ◽  
pp. 415-424
Author(s):  
Konstantin D. Bergmeister ◽  
Stefan Salminger ◽  
Oskar C. Aszmann

Neurosurgery ◽  
2018 ◽  
Vol 65 (CN_suppl_1) ◽  
pp. 86-86 ◽  
Author(s):  
Lauren M Mioton ◽  
Gregory A Dumanian ◽  
Jennie Cheesborough ◽  
Ian Valerio

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