This essay examines the figure of the pesticide-exposed intersex frog, a canary in the coal mine for public endocrinological health. Through feminist science studies and critical discourse analysis, I explore the fields that bring this figure into being (endocrinology, toxicology, and pest science) and the colonial and racial logics that shape these fields. In so doing, I attend to the multiple nonhuman actors shaping this figure, including the pesky weeds and insects who prompt pesticides’ very existence, “male” frogs who function as test subjects, and systemic environmental racism that disproportionately exposes people of color to environmental toxicants. I encourage careful examination of galvanizing environmental figures like this toxic intersex frog and I offer a method to do so.