scholarly journals A Case of an Ischemic Regio Sacralis Ulcer Due to Internal Iliac Artery Stenosis Resembling Clinical Presentation of Deep Tissue Injury

2021 ◽  
Vol 61 (4) ◽  
pp. 19-24
Author(s):  
Ranko Hinooka ◽  
Shinsuke Kikuchi ◽  
Ai Tochikubo ◽  
Seima Ohira ◽  
Takamitsu Tatsukawa ◽  
...  
Keyword(s):  
Iliac Artery ◽  
Clinical Presentation ◽  
Internal Iliac Artery ◽  
Tissue Injury ◽  
Artery Stenosis ◽  
Deep Tissue ◽  
Deep Tissue Injury ◽  
Iliac Artery Stenosis ◽  
Internal Iliac

scholarly journals Internal Iliac Artery Stenosis: Diagnosis and How to Manage it in 2015

2015 ◽  
Vol 2 ◽  
Author(s):  
Guillaume Mahé ◽  
Adrien Kaladji ◽  
Alexis Le Faucheur ◽  
Vincent Jaquinandi
Keyword(s):  
Iliac Artery ◽  
Internal Iliac Artery ◽  
Artery Stenosis ◽  
Iliac Artery Stenosis ◽  
Internal Iliac

Two cases of buttock claudication caused by isolated internal iliac artery stenosis

VASA ◽  
2006 ◽  
Vol 35 (3) ◽  
pp. 209-211 ◽  
Author(s):  
Kahle ◽  
Schmidt-Lucke
Keyword(s):  
Iliac Artery ◽  
Internal Iliac Artery ◽  
Transluminal Angioplasty ◽  
Artery Stenosis ◽  
Adequate Treatment ◽  
Iliac Arteries ◽  
Iliac Artery Stenosis ◽  
Buttock Claudication ◽  
Internal Iliac ◽  
Percutaneous Transluminal

We present two cases of buttock claudication caused by severe stenosis of the internal iliac artery which disappeared totally after percutaneous transluminal angioplasty (PTA). Isolated stenoses of internal iliac arteries are rare. It is often difficult to distinguish between vascular buttock claudication and neurological or orthopaedic symptoms. Conventional or MR-angiography is necessary to secure the diagnosis. PTA of internal iliac artery stenosis is the adequate treatment.

scholarly journals Endovascular Treatment of Internal Iliac Artery Stenosis in Patients with Buttock Claudication

PLoS ONE ◽  
2013 ◽  
Vol 8 (8) ◽  
pp. e73331 ◽  
Author(s):  
Jip F. Prince ◽  
Maarten L. J. Smits ◽  
Joost A. van Herwaarden ◽  
Mark J. Arntz ◽  
Evert-Jan P. A. Vonken ◽  
...  
Keyword(s):  
Endovascular Treatment ◽  
Iliac Artery ◽  
Internal Iliac Artery ◽  
Artery Stenosis ◽  
Iliac Artery Stenosis ◽  
Buttock Claudication ◽  
Internal Iliac

Revascularisation in transplant renal artery stenosis using the internal iliac artery

2003 ◽  
Vol 35 (1) ◽  
pp. 332-333
Author(s):  
M Shrotri ◽  
S Sudhindran ◽  
B.S Fernando ◽  
G Pettigrew ◽  
C.J Watson ◽  
...  
Keyword(s):  
Renal Artery ◽  
Renal Artery Stenosis ◽  
Iliac Artery ◽  
Internal Iliac Artery ◽  
Artery Stenosis ◽  
Transplant Renal Artery Stenosis ◽  
Internal Iliac

Healing effects of curcumin nanoparticles in deep tissue injury mouse model.

2020 ◽  
Vol 18 ◽  
Author(s):  
Zirui Zhang ◽  
Shangcong Han ◽  
Panpan Liu ◽  
Xu Yang ◽  
Jing Han ◽  
...  
Keyword(s):  
Wound Healing ◽  
Mrna Expression ◽  
Tissue Injury ◽  
Inflammatory Cells ◽  
Pcr Analysis ◽  
Protective Effects ◽  
Deep Tissue ◽  
Deep Tissue Injury

Background: Chronic inflammation and lack of angiogenesis are the important pathological mechanisms in deep tissue injury (DTI). Curcumin is a well-known anti-inflammatory and antioxidant agent. However, curcumin is unstable under acidic and alkaline conditions, and can be rapidly metabolized and excreted in the bile, which shortens its bioactivity and efficacy. Objective: This study aimed to prepare curcumin-loaded poly (lactic-co-glycolic acid) nanoparticles (CPNPs) and to elucidate the protective effects and underlying mechanisms of wound healing in DTI models. Methods: CPNPs were evaluated for particle size, biocompatibility, in vitro drug release and their effect on in vivo wound healing. Results : The results of in vivo wound closure analysis revealed that CPNP treatments significantly improved wound contraction rates (p<0.01) at a faster rate than other three treatment groups. H&E staining revealed that CPNP treatments resulted in complete epithelialization and thick granulation tissue formation, whereas control groups resulted in a lack of compact epithelialization and persistence of inflammatory cells within the wound sites. Quantitative real-time PCR analysis showed that treatment with CPNPs suppressed IL-6 and TNF-α mRNA expression, and up-regulated TGF-β, VEGF-A and IL-10 mRNA expression. Western blot analysis showed up-regulated protein expression of TGF-β, VEGF-A and phosphorylatedSTAT3. Conclusion: Our results showed that CPNPs enhanced wound healing in DTI models, through modulation of the JAK2/STAT3 signalling pathway and subsequent upregulation of pro-healing factors.

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