scholarly journals Aggressive, Metastatic Squamous Cell Carcinoma After a 46-Year-Old History of Chronic Osteomyelitis and Local Infectious Complications: A Case Report

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Roberto Manfredi ◽  
Sergio Sabbatani ◽  
Filippo Trapani ◽  
Calogero Alfonso ◽  
Massimo Laus

Marjolin’s ulcer is a squamous cell carcinoma (SCC) arising from any site of established chronic inflammation, especially with presence of scar tissue.An emblematic case report of locally disseminated SCC arising from a chronic osteomyelitis of the left leg complicated by recurring soft tissue infections lasting since 46 years is presented and discussed according to the available international literature evidence. Concurrent diseases, supporting factors, clinical and histopathological presentation, differential diagnosis, and time and mode of management of this potentially functional- and life-threatening pathological condition are reviewed and discussed to offer a theme to daily clinical care.

2010 ◽  
Vol 59 (4) ◽  
pp. 852-854
Author(s):  
Takuya Oyaizu ◽  
Hiroaki Tamura ◽  
Masayuki Kawashima ◽  
Mahito Kawashima

2019 ◽  
Vol 7 (18) ◽  
pp. 3061-3063 ◽  
Author(s):  
Uwe Wollina ◽  
Claudia Krönert ◽  
Jacqueline Schönlebe ◽  
Aleksandra Vojvodic ◽  
Torello Lotti

BACKGROUND: Cutaneous squamous cell carcinoma (SCC) is the second most common malignancy of skin. Although a major risk factor is a chronic exposure to ultraviolet radiation, preexistent chronic inflammatory disorders may also possess an increased risk for SCC. That is not the case for cutaneous lichen planus in contrast to oral lichen planus and oral SCC.  CASE REPORT: We report the case of an 87-year-old Caucasian woman presenting with a giant verrucous tumour on the left ankle. She suffered from long-standing disseminated lichen planus. Histology confirmed the diagnosis of SCC on partly verrucous lichen planus. The course was complicated due to sepsis. An emergency transfemoral amputation became necessary. The patients survived and could be released into her nursery. A literature review underlined the rarity of SCC on lichen planus of the skin. Most of these rare cases were in patients in their second half of life on the lower legs. Hypertrophic lichen plnaus was overrepresented.   CONCLUSIONS: Although very rare by number, SCC can complicate lichen planus and lead to the life-threatening situation. Atypical verrucous lesions on lichen planus warrant a histologic analysis. Surgery is the treatment of choice for cutaneous SCC.


2019 ◽  
Vol 7 (18) ◽  
pp. 3030-3033 ◽  
Author(s):  
Uwe Wollina ◽  
Thomas Kittner ◽  
Andreas Nowak

BACKGROUND: Skin cancer is an uncommon cause of skull invasion, dural infiltration and brain parenchyma involvement. CASE REPORT: We report on a series of three elderly patients who presented with squamous cell carcinoma of the scalp with skull bone and cerebral invasion and discuss the diagnostic and therapeutic challenges. CONCLUSION: A major factor of delayed diagnosis of this potentially life-threatening skin cancer feature is patients’ neglecting.


Foot & Ankle ◽  
1991 ◽  
Vol 12 (3) ◽  
pp. 178-181 ◽  
Author(s):  
Robert J. Ziets ◽  
Phillip M. Evanski ◽  
Ralph Lusskin ◽  
Michael Lee

Squamous cell carcinoma arising from chronic osteomyelitis is uncommon. Although the majority of cases occur in the lower extremity, incidence in the foot is relatively rare, and in the toe, exceptional. This report illustrates a particularly unusual incidence of squamous cell carcinoma complicating chronic osteomyelitis of the hallux. Guidelines for early diagnosis, recommendations for treatment, and prognostic data are included.


2016 ◽  
Vol 74 (5) ◽  
pp. 344
Author(s):  
Donghwa Han ◽  
Jihae Lee ◽  
Woo Ho Cho ◽  
Jae Hyung Kim ◽  
Myeong Ja Jeong ◽  
...  

1993 ◽  
Vol 79 (4) ◽  
pp. 286-287 ◽  
Author(s):  
Mario Airoldi ◽  
Pietro Gabriele ◽  
Giovanni Succo ◽  
Guido Valente ◽  
Vincenzo Brando

Small bowel metastases from squamous cell carcinoma of the head and neck are relatively rare and in some cases asymptomatic. In the case herein reported, small bowel metastasis from a laryngeal carcinoma caused a life-threatening complication. The surgical approach was effective in saving the patient's life. Death occurred for neck tumor progression without abdominal signs of secondary lesions. A review of the previously reported cases is provided.


2019 ◽  
Vol 16 ◽  
pp. 100289 ◽  
Author(s):  
Taisei Kurihara ◽  
Yoshiyuki Suehara ◽  
Keisuke Akaike ◽  
Takuo Hayashi ◽  
Taketo Okubo ◽  
...  

2016 ◽  
Vol 10 (1) ◽  
Author(s):  
Gaetano Caruso ◽  
Emanuele Gerace ◽  
Vincenzo Lorusso ◽  
Rosario Cultrera ◽  
Loredana Moretti ◽  
...  

2020 ◽  
Vol 10 (12) ◽  
pp. 419-424
Author(s):  
Xi Yuan Ang ◽  
Yuet Yang Tan ◽  
Mohd Atiq Che Roselam ◽  
Mohamad Hafiz Mohmad Hassim ◽  
Raeross Anak Jabul

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