scholarly journals Author response: Vitamin A supplements, routine immunization, and the subsequent risk of Plasmodium infection among children under 5 years in sub-Saharan Africa

2014 ◽  
Author(s):  
Maria-Graciela Hollm-Delgado ◽  
Frédéric B Piel ◽  
Daniel J Weiss ◽  
Rosalind E Howes ◽  
Elizabeth A Stuart ◽  
...  
2012 ◽  
Vol 90 (7) ◽  
pp. 495-503 ◽  
Author(s):  
Stephane Helleringer ◽  
Jemima A Frimpong ◽  
Jalaa Abdelwahab ◽  
Patrick Asuming ◽  
Hamadassalia Touré ◽  
...  

PLoS ONE ◽  
2019 ◽  
Vol 14 (7) ◽  
pp. e0220023
Author(s):  
Amanda Garrison ◽  
Babak Khoshnood ◽  
David Courtin ◽  
Jacqueline Milet ◽  
André Garcia ◽  
...  

Foods ◽  
2019 ◽  
Vol 8 (5) ◽  
pp. 177 ◽  
Author(s):  
Toluwalope Emmanuel Eyinla ◽  
Busie Maziya-Dixon ◽  
Oladeji Emmanuel Alamu ◽  
Rasaki Ajani Sanusi

Plant breeding efforts in sub-Saharan Africa (SSA) have produced biofortified cassava with high carotenoid content to address vitamin A deficiencies (VAD). Since carotenoids in foods are easily depleted during processing, the retention of β-carotene in some newly released cassava varieties is under query. From four of these new varieties, two commonly consumed products (gari and its dough) were processed according to standard methods. Retention of β-carotene was then probed after applying fermentation periods of a day and three days. The possible contribution of the products to Vitamin A intake in children, adolescents, and women was also assessed. The concentration of β-carotene in fresh Cassava roots ranged from 5.32 to 7.81 µg/g. The percentage retention ranged from 14.4 to 29.3% and 10 to 21.7% in gari fermented for one and three days respectively. The impact of varietal difference and length of fermentation was significant on retention in the intermediate and final products (p < 0.001). When compared with dietary intake data, cooking biofortified gari into its dough reduced Vitamin A intake in most varieties. We conclude that processing Cassava into gari (especially its dough) could hinder the retention of β-carotene however some varieties have retention advantage over others irrespective of the initial concentration in their fresh roots.


2016 ◽  
Vol 21 (8) ◽  
pp. 943-955 ◽  
Author(s):  
Francois Kiemde ◽  
René Spijker ◽  
Petra F. Mens ◽  
Halidou Tinto ◽  
Michael Boele ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Omololami Tolulope Akinsola ◽  
Emmanuel Oladeji Alamu ◽  
Bolanle Omolara Otegbayo ◽  
Abebe Menkir ◽  
Busie Maziya-Dixon

Provitamin-A maize (PVA) with increased carotenoid content obtained through conventional breeding techniques has been largely successful in sub-Saharan Africa. This resulted in a need to evaluate their susceptibility, retention, and nutritional content during processing into local foods. This study evaluated the chemical, carotenoid composition, and retention of PVA, the phytic acid content in ogi powder, and the sensory perception of ogi porridge produced traditionally from the three novel PVA maize genotypes (PVA SYN HGAC0 Maize 1; PVA SYN HGBC0 Maize 2; and PVA SYN HGBC1 Maize 3) and one yellow maize variety (control). Chemical composition analyses showed significant differences (p &lt; 0.05) in all parameters. The PVA ranged from 5.96 to 8.43 μg/g in Maize 2 and 3 before processing while the true percentage retention after processing into ogi powder ranged from 20.25 to 37.54% in Maize 1 and 2, respectively. In addition, there was a reduction in the phytate content of ogi powder, and Maize 2 contained the lowest (2.78 mg/g from 4.09 mg/g). Maize 2 genotype had the highest vitamin A contribution; it can meet 18.3% of the vitamin A requirements in children while in adult males and females (&gt;19 years), 6.2 and 7.7%, respectively. Sensory evaluation showed that the ogi 3 porridge (Maize 3) was the most acceptable, followed by Maize 2. In conclusion, Maize 2 had the highest PVA, true retention of carotenoid, vitamin A contributions, and the second most acceptable ogi porridge with the lowest phytate content.


2020 ◽  
Vol 148 ◽  
Author(s):  
T. B. Oppong ◽  
H. Yang ◽  
C. Amponsem-Boateng ◽  
E. K. D Kyere ◽  
T. Abdulai ◽  
...  

Abstract Gastroenteritis remains a serious health condition among children under 5 years especially in Africa. We conducted a systematic review and meta-analysis to investigate the aetiologic pathogens of gastroenteritis in the region. We did a systematic search for articles with original data on the aetiology of gastroenteritis and acute diarrhoea among children younger than 5 years. Pooled results were extracted and analysed in STATA version 12.0 using random-effects for statistical test for homogeneity following the guidelines provided in the Cochrane Collaboration and Preferred reporting items for systematic reviews and meta-analyses. Overall, viruses accounted for 50.2% of the cases followed by bacteria with 31.6% of the cases. Parasites accounted for 12.1% of the case. Rotavirus was the most common cause of acute diarrhoea in all regions resulting in 29.2% of the cases followed by E. coli (15.6%) of diarrhoeal cases and Adenovirus (10.8%). The most prevalent parasite detected was Giardia lamblia (7.3%). Acute diarrhoea remains rampant with Rotavirus still being the major pathogen responsible for the disease in children less than 5 years old despite the introduction of vaccine. It is recommended that the vaccine should be promoted much more widely in the region.


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