scholarly journals Buddleja asiatica Derived Phytochemicals against Diarrhea

Author(s):  
Dipankar Bhattacharyay

Plants produce nonnutritive compounds that are often extracted to make herbal medicines. It has been reported that extracts of Buddleja asiatica are effective to treat diarrhea. One of the causes of Diarrhea is an infection by Campylobacter jejuni. The objective of the study is to identify the phytochemical of Buddleja asiatica capable of curing Diarrhea. ATP-phosphoribosyl transferase enzyme plays an important role in Purine Metabolism. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Lignoceric acid can effectively deactivate the transferase enzyme thereby interrupting the life cycle of the organism.

Author(s):  
Debajani Tripathy ◽  
Chandana Adhikari ◽  
Mukundjee Pandey ◽  
Dipankar Bhattacharayay

Phytochemicals from Bhringaraj plant extract are traditionally used to cure Pneumonia. It is caused by Klebsiella pneumonia. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that glutamic acid can effectively deactivate the dehydrogenase enzyme, thereby interrupting the life cycle of the organism.


Author(s):  
Bidyashree Tripathy ◽  
Elina Sahoo ◽  
Sidhartha Ray ◽  
Soumya Jal ◽  
Dipankar Bhattacharyay

Phytochemicals from Trigonella foenum-graecum plant extract are traditionally used to cure Tuberculosis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that this plant extract can effectively deactivate the dihydrofolate reductase enzyme thereby interrupting the life cycle of the organism.


Author(s):  
Sanjeeb Kumar Dash ◽  
Sidhartha Ray ◽  
Smruti Ranjan Behera ◽  
Soumya Jal ◽  
Dipankar Bhattacharyay

Phytochemicals from Michelia champaca L. plant extract are traditionally used to cure cough.  Cough can be caused by many reasons. Caugh can be caused by the infection of Bordetella pertussis. The objective of the study is to identify the phytochemical of Michelia champaca capable of curing cough. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that magnoflorine can effectively deactivate the peptidase Do enzyme which will interrupt the life cycle of the microorganism and inhibit the multiplication.


Author(s):  
Debadatta Nayak ◽  
Debesh Kumar Hota ◽  
Tophani Sahu ◽  
Soumya Jal ◽  
Dipankar Bhattacharyay

Phytochemicals from Capsicum anum L. plant extract are traditionally used to cure bronchitis. Bronchitis is caused by Haemophilus influenzae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that myrcetin and quercetin can effectively deactivate the Palmitoyl-CoA hydrolase enzyme thereby interrupting the life cycle of Haemophilus influenza.


Author(s):  
Debasmita Das ◽  
Sonu Priya Sahu ◽  
Sunanya Das ◽  
G. K. Panigrahi ◽  
Sitaram Swain ◽  
...  

Phytochemicals from Syzygium aromaticum plant extract traditionally used to cure Feet Crack. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Myricetin can effectively deactivate the dihydrofolate reductase enzyme thereby interrupting the life cycle of the organism.


Author(s):  
Sonupriya Sahu ◽  
Ashok Kumar Sahoo ◽  
Rukmini Mishra ◽  
G. K. Panigrahi ◽  
Sonali Dash ◽  
...  

Phytochemicals are produced by plants as secondary metabolites to protect the plants from predators. When the parts of the plant, which are rich in different phytochemical constituents, are consumed by humans, they can cure different diseases. Phytochemicals from Santalum album plant extract are traditionally used to cure Jaundice. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Isohamnetin can effectively deactivate the enzyme, thereby interrupting the life cycle of the organism.


Author(s):  
Debesh Kumar Hota ◽  
Debadatta Nayak ◽  
Sitaram Swain ◽  
Dipankar Bhattacharyay

Phytochemicals from Capsicum plant extract are traditionally used to cure Bronchitis. It is caused by Haemophilus influenzae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Apigenin can effectively deactivate the Shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.


Author(s):  
Utapa Nayak ◽  
Elora Barik ◽  
Bijan Kumar Patra ◽  
Smruti Ranjan Behera ◽  
Mukundjee Pandey ◽  
...  

Alkanna tinctoria plant extract is traditionally used to heal eczema. It is caused by Staphylococcus aureus. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 2-Hydroxy-3-Phenyl-1-4-naphthoquinone can can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.


Author(s):  
Chinmayee Naik ◽  
Krutanjali Rout ◽  
Mukundjee Pandey ◽  
Ipsita Priyadarsini Samal ◽  
Shibani Sahoo ◽  
...  

Phytochemicals from Boswellia serrata Roxb. ex Colebt. plant extract are traditionally used to cure diarrhea. It is caused by Escherichia coli. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that p-cymene can effectively deactivate the alcohol dehydrogenase enzyme thereby interrupting the life cycle of the organism.


Author(s):  
Sonali Parida ◽  
Jogesh Kumar Nayak ◽  
Anindita Jena ◽  
Arsia Tabish ◽  
Archita Sahoo ◽  
...  

Phytochemicals from Bixa orellana plant extract are traditionally used to cure Dysentery. It is caused by Entamoeba histolytica. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that benzoin acid can effectively deactivate the alcohol dehydrogenase enzyme thereby interrupting the life cycle of the organism.


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