scholarly journals Review on Theobromine: An Alternative to Fluorides in Treating Dentinal Hypersensitivity

Author(s):  
Shailee Chandak ◽  
Priyanka Paul Madhu ◽  
Kumar Gaurav Chhabra ◽  
Amit Reche ◽  
Gopika Mahure ◽  
...  

Theobromine is a unique constituent that can help dentistry and general health in the future. The generic name of theobroma is obtained from two Greek words i.e., Theo and Broma, which means “food of the gods". It can be found in cocoa beans and chocolates. Theodent toothpaste harness the power of cocoa. Rennou, the main component in Theodent, is a unique compound that combines theobromine, calcium, and phosphate to enhance enamel remineralization. This article is to review the effectiveness of theobromine in blocking dentinal tubules by preventing dentinal hypersensitivity, and its positive effects on general health. Various researches and valid documents were reviewed by us. Several studies have been conducted that shows theobromine is effective in blocking dentinal tubules, thus preventing dentinal hypersensitivity as well as tooth demineralization. It also has other general health benefits. Because of its potent vasodilation, diuretic and heart stimulant effect, theobromine can also be used in treating high blood pressure. It also aids in opening of airways and helps in preventing kidney stones. The use of fluoride dentifrices is debatable, as it has many detrimental effects. Also, we consider that theobromine if used as a component in dentifrices, if unintentionally swallowed, cause no catastrophic effects.

2019 ◽  
Vol 25 (6) ◽  
pp. 700-709 ◽  
Author(s):  
Shuangshuang Zhang ◽  
Yong Wang ◽  
Jinsong Cheng ◽  
Ning Huangfu ◽  
Ruochi Zhao ◽  
...  

Purine metabolism in the circulatory system yields uric acid as its final oxidation product, which is believed to be linked to the development of gout and kidney stones. Hyperuricemia is closely correlated with cardiovascular disease, metabolic syndrome, and chronic kidney disease, as attested by the epidemiological and empirical research. In this review, we summarize the recent knowledge about hyperuricemia, with a special focus on its physiology, epidemiology, and correlation with cardiovascular disease. This review also discusses the possible positive effects of treatment to reduce urate levels in patients with cardiovascular disease and hyperuricemia, which may lead to an improved clinical treatment plan.


Author(s):  
Nick Yiannios, DDS

In the literature, Dentinal Hypersensitivity (DH) is considered to arise from exposed dentin and patent dentinal tubules. However, clinical observation of recurrent DH sensitivity indicates it can occur in the presence or absence of exposed dentin. Quantified occlusal contact force and timing parameters have been ignored in studies assessing hypersensitive teeth. This chapter introduces a novel occlusal concept: Frictional Dental Hypersensitivity (FDH). Clinical evidence from combining computerized occlusal analysis and electromyography is presented linking opposing posterior tooth friction and muscular hyperactivity to Dentin Hypersensitivity. This chapter proffers how occlusion, muscular TMD symptoms, and frictional Dentin Hypersensitivity are all related. Lastly, a Pilot Study is presented that used a Visual Numerical Analog scale to quantify Dentin Hypersensitivity resolution observed in symptomatic patients who underwent the Immediate Complete Anterior Guidance Development (ICAGD) coronoplasty. This computer-guided occlusal adjustment eliminated pretreatment FDH symptomatology, further supporting that Dentinal Hypersensitivity has an occlusally-based, frictional etiology.


2011 ◽  
Vol 1 (3) ◽  
pp. 1-15 ◽  
Author(s):  
Wolfgang Bösche ◽  
Florian Kattner

Digital games and their power as a tool for acquiring knowledge, training skills and changing behavior are – for some laymen – associated with rather negative concepts, and are thought to pose a general health risk. This paper shortly reviews and evaluates the scientific evidence for both positive and negative outcomes. It describes how particularly the negative effects are portrayed by the mass media and perceived by the general public and educators (especially in Germany). The conclusion is that negative effects such as addiction or personality changes towards aggression have been exaggerated in size, and that the positive effects and outcomes like their use as educational tools are at risk of being widely ignored. Additionally, the paper reports upon observations in a university lecture on the effects of violent digital games in which students could engage in a positive, healthy and enjoyable experience of learning with digital games.


Author(s):  
Annelie Khatami ◽  
Kristina Rosengren

Purpose Purpose - The aim was to describe an improvement project and its effects on decreasing the time from diagnosis to treatment for patients with kidney stones and to reduce the negative effects related to untreated stones at one hospital in western Sweden Design/methodology/approach Design and methodology - A quantitative descriptive study based on Nolan’s improvement model was used. The quality improvement effects were evaluated using statistical process control (SPC). Findings Findings – Extracorporeal shock wave lithotripsy ESWL treatment’s positive effects within 48 hours were described as efficiency (decreased waiting time) from diagnosis to treatment, even if a re-treatment was necessary. The results also showed a reduction in the usage of percutaneous nephropyelostomies as a treatment option. Research limitations/implications Research limitations - This study includes data from one department at one hospital in one country. Comparative data include the time from acute radiological examination to final treatment but not total re-treatments, complications or time to up following radiological examination. However, the study was performed over one year and analyzed data from medical records in a systematic way. Practical implications Practical implications - This study may inspire measuring and developing routines from diagnosis to treatment for patients who are transferred within different departments at one hospital. Originality/value Originality - Studies in improvement projects considering ureteral or kidney stones are generally lacking; thus, this study is important for improving the care of patients with this diagnose.


2014 ◽  
Vol 02 (01) ◽  
pp. 016-021
Author(s):  
Ashu Gupta ◽  
Neha Sharma ◽  
Manmohan Bramta

AbstractDentinal hypersensitivity (DH) is a painful clinical condition and is characterized by pain arising from exposed dentin in response to various stimuli. Various treatment modalities are available to treat dentinal hypersensitivity which include at-home and in-office treatment. At home treatment generally consists of a variety of dentrifices containing different constituents like stannous fluoride, strontium chloride and potassium oxalate. These agents cause occlusion of dentinal tubules which decreases both dentine permeability and fluid movement thereby reducing hypersensitivity. Recently, bioactive glass (NovaMin) has been incorporated as a remineralising ingredient in dentifrice formulations for treating Dentinal Hyprsensitivity. It relieves the symptoms by precipitating hydroxycarbonate apatite (HCA) onto the tooth surface. Another combination product consisting of an aqueous solution of 5% glutaraldehyde and 35% hydroxyethyl methacrylate (Gluma desensitizer) has also been reported to be an effective desensitizing agent. Thus, the aim of the study was to evaluate and compare the tubule occluding effect of of two desensitizing agents, which are bioactive glass (Novamin), and Gluma Desensitizer. In the present study bioactive glass was found to produce more completely occluded tubules while Gluma desensitizer caused more partial occlusion on initial application. Hence, NovaMin application could be more effective in providing relief from dentinal hypersensitivity when compared with Gluma Desensitizer.


2020 ◽  
Vol 49 (3) ◽  
pp. 19-27
Author(s):  
Sergio M. Pico-Hernández ◽  
Cristian J. Murillo-Méndez ◽  
Luis J. López-Giraldo

Polyphenol Extracts (PE) hold antioxidant properties, which might be related to positive effects on human health. It has been stated that PE, obtained from cocoa beans, contain fractions of flavan-3-ols with different degrees of polymerization (DP). However, it is unknown which of the fractions or their mixture drives the best antioxidant activity. This paper reports the study conducted to elucidate the role of each fraction (with different DP) on Antioxidant Capacity (AC). First, the process of extraction and separation of polyphenols’ fractions in cocoa beans was executed; afterward, AC was determined for each fraction individually and their combinations (monomers, dimers and oligomers). Solid-liquid extraction was made by using a 50% (v/v) ethanol solution and a mass:solvent ratio of 1:120 in an ultrasound bath. PE were separated into monomers, dimers, and oligomers by HPLC using a semipreparative column. The results obtained show that PE contain 95.35, 7.45, and 21.75 mg EE (epicatechin equivalents) / g ds of monomers, dimers, and oligomers, respectively. Finally, the AC of each fraction  was evaluated using a complete cubic model mix design. According to the results, the best AC was obtained for dimers. However, when monomers, dimers and oligomers were mixed, an antagonistic effect on AC was observed.


Author(s):  
Dr. Madhavi Ajit Shetty ◽  
Dr. Sharad Kokate ◽  
Dr. Vibha Hegde

Aim: To comparatively evaluate the occlusion of dentinal tubules by four novel desensitizing agents for treatment of Dentinal Hypersensitivity. Materials and Methods: The Diode Laser and three commercially available Desensitizers the NovaminR group- (SHY-NMTM), Colgate Sensitive Pro-relief, Gluma were investigated in this study. 30 extracted mandibular molars were used (n=30). They were divided into 5 groups including the control group in which no treatment was done. Teeth were ground under water-cooled trimming wheel, to prepare flat dentin surfaces. The dentin surfaces were etched to remove any smear plugs and to mimic the open dentinal tubules of sensitive dentin using 0.5 M Ethylene Diamine Tetraacetic Acid (pH 7.4) for two minutes (applied with a micro brush) and then rinsed with an air-water syringe for 30 seconds.


Author(s):  
Wolfgang Bösche ◽  
Florian Kattner

Digital games and their power as a tool for acquiring knowledge, training skills and changing behavior are – for some laymen – associated with rather negative concepts, and are thought to pose a general health risk. This paper shortly reviews and evaluates the scientific evidence for both positive and negative outcomes. It describes how particularly the negative effects are portrayed by the mass media and perceived by the general public and educators (especially in Germany). The conclusion is that negative effects such as addiction or personality changes towards aggression have been exaggerated in size, and that the positive effects and outcomes like their use as educational tools are at risk of being widely ignored. Additionally, the paper reports upon observations in a university lecture on the effects of violent digital games in which students could engage in a positive, healthy and enjoyable experience of learning with digital games.


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