Dietary Fat and Polyunsaturated Fatty Acid Intakes during Childhood Are Prospectively Associated with Puberty Timing Independent of Dietary Protein

Dietary fat and fat quality have been inconsistently associated with puberty timing. The aim of this study was to investigate the prospective associations of dietary fat, saturated fatty acid (SFA), polyunsaturated fatty acid (PUFA), and monounsaturated fatty acid (MUFA) with puberty timing. Using longitudinal data from China Health and Nutrition Survey (CHNS) and Southwest China Childhood Nutrition and Growth (SCCNG) Study, we analyzed dietary data, anthropometric measurements, and potential confounders. Dietary intakes were assessed by 3-day 24-h recalls. Age at Tanner stage 2 for breast/genital development (B2/G2) and age at menarche/voice break (M/VB) were used as puberty development markers. Cox proportional hazard regression models were used to estimate the relevance of dietary intake of total fat, SFA, PUFA, and MUFA on puberty timing. Among 3425 girls and 2495 boys, children with higher intakes of total fat and PUFA were more likely to reach their B2/G2 or M/VB at an earlier age. Associations were not attenuated on additional adjustment for childhood dietary protein intake. However, higher intakes of SFA or MUFA were not independently associated with puberty development. A higher intake of dietary fat and PUFA in prepuberty was associated with earlier puberty timing, which was independent of dietary protein intake.

Metabolic syndrome in middle-aged and older women: A cross-sectional study

Objective: This study aims to compare the prevalence of metabolic syndrome between different age groups of middle-aged and older women and to assess whether these differences are independent of potential covariates. Methods: Study conducted with 510 women divided into three age groups: 45–54, 55–64 and 65–74 years. Socioeconomic, reproductive and lifestyle variables were self-reported. We defined metabolic syndrome using the National Cholesterol Education Program Adult Treatment Panel III criteria (abdominal obesity, diabetes, reduced high-density lipoprotein, elevated triglycerides, and hypertension). Logistic regression assessed the association between age groups, and metabolic syndrome was adjusted for covariates (socioeconomic variables, age at menarche and at first childbirth, parity, menopausal status, physical activity variables and smoking). Results: Women aged 55–64 years presented higher prevalence of all metabolic syndrome criteria than the other groups, except for abdominal obesity, which was higher in the oldest group. In the fully adjusted analysis, the 55–64 years age group continues to exhibit significantly higher odds of presenting metabolic syndrome when compared to the youngest group (45–54 years) (OR = 2.257; 95% CI = 1.20:4.24). There was no statistical difference in the odds of presenting metabolic syndrome when comparing the oldest and the youngest groups (OR = 1.500; 95% CI = 0.85:2.65). Conclusion: The higher prevalence of metabolic syndrome among those aged 55–64 years may indicate that middle-aged women become unhealthy earlier in the life course and that many of them may die prematurely. This result highlights the importance of screening metabolic syndrome earlier in the midlife and the need for public health policies aimed at reducing adverse effects in later years.

Menstrual cycle among adolescents: girls’ awareness and influence of age at menarche and overweight

Objective: To characterize the menstrual cycle (regularity and menstrual flow length), the prevalence of dysmenorrhea and self-monitoring of the cycle in students from Lisbon region, and explore the effect of chronological age, age at menarche and body mass index (BMI) on menstrual disorders. Methods: This is a cross-sectional study with 848 girls aged 12–18 years. A questionnaire about the sociodemographic context and characteristics of the menstrual cycle, and weight and height measures were assessed. BMI was classified according to International Obesity Taskforce criteria. A descriptive analysis of the variables was made, and Odds Ratios (ORs) and 95% confidence intervals (95%CIs) were determined. Results: Mean age at menarche was 12.4 years and mean BMI was 22.0kg/m2. Among adolescents, 59% have regular menstrual cycle, 83% have menstrual flow length of ≤6 days. 88% suffered from dysmenorrhea, among which 8,7% declare absenteeism from school and 49% took pain medication, and 65% self-monitor their menstrual cycle. Higher maternal education was associated with a higher self-monitoring of menstrual cycle among the sample (OR 1.60; 95%CI 1.15–2.17). Girls with menarche <12 years-of-age are more likely to have menstrual flow length of >6 days (OR 1.73; 95%CI 1.19–2.51) and dysmenorrhea (OR 1.87; 95%CI 1.11–3.16) than those with menarche ≥12 years-of-age. No significant association between BMI and menstrual cycle variables was observed. Conclusions: The results suggest that menstrual disorders are frequent and may be associated with early menarche, but not with BMI. It is important to encourage self-monitoring of the menstrual cycle to detect menstrual disorders timely and promote health and well-being.

Age, seasons and influence of body mass index on menarche among secondary school girls in Port Harcourt, Nigeria

Menarche is a significant marker of maturity and puberty in girls, and it is a transition influenced by different biophysical factors. This study was carried out to determine the age, seasons and the influence of body mass index (BMI) on menarche. A total of 450 girls’ between the ages of 10 and 19 years participated in the study. Age at menarche was obtained via the recall quo cross sectional method. Parameters measured were; standing height (SH), weight (Wt) and BMI. A total of 373 (82.9%) girls had their menarche in their early adolescence while 77 girls (17.1%) had their menarche in mid adolescence. Mean age at menarche was 13.17± 1.48 years. The average value for BMI was 20.35 ± 3.77 kg/m2, SH was 161.09 ± 6.16 cm, Wt was 52.53 ± 9.21kg. Overweight girls were observed to attain menarche earlier, followed by those whose mean weight was in the normal range .Subjects in the underweight category had higher age at menarche. Menarche was high in the months of August, July and January. Menarche occurs early among secondary school girls in Port Harcourt and among other factors, those associated with BMI and stress are important in the onset of the biological event.

Adolescents Nutritional Association (Micronutrients) with Menarche: Role of Health Schemes and Services in India

Menarcheal age in adolescent girls marks an important health concern in women's biology. The timing of menarche is an important determinant of Population size, Reproductive health and is an important factor of Health planning. The paper aimed to find the current mean age at menarche in India and its Nutritional association with micronutrients (given the role of government schemes and services). To fining out about the same the Menarcheal age group of (10-19 years) in India are examined. Binary logistic regression model is used to to estimate the association in the Menarcheal age among the Adolescent using the Comprehensive National Nutritional Survey. The mean age at menarche among adolescents stands at 9.07 years (95% C.I.: 8.990,9.166), including the non menstruating girls within the concerned age group,the mean age was 12.815 years (95% C.I.: 12.837,12.793). Girls with anemia are more likely to have their menarche 0.364 years higher than girls who are non amenic. The mean age at menarche is 0.72 years more likely to occur among those who have multivitamin tables/ syrup. The study concludes that over the time the age at menarche has declined rapidly with economic growth, urbanisation, Improvements in the Nutritional intake ( addition of Micronutrients also seen a contributing factor). The area of concern with regard to Micronutrients supplementation is that, it is done so to provide proper nutritional factors but on the other hand is also causing early Mnearche that most of the Health scientists warned and seen it as a cause for ovarian, breat cancers and other diseases amongst girls in future. Hence its imprtant to keep a proper check on the dietary intake among girls at early stages of life.

Assessment of an Educational Intervention on the Perception of Adolescent Girls towards Menstrual Hygiene in Ogun State, Nigeria

In low and middle-income countries, menstruation is impeded by several misconceptions, taboos and shrouded in secrecy. This serves as a major challenge to proper Education regarding menstrual hygiene and has blocked the access of adolescent girls to the right kind of information, thereby influencing a negative outcome associated with harmful behaviours. The objective of the study was to investigate the assessment of an educational intervention on the perception of adolescent girls towards menstrual hygiene in Ogun state, Nigeria. The study utilized a quasi-experimental design. One hundred and twenty (120) in-school adolescent girls were selected through a multistage sampling technique from four (4) secondary schools within four (4) local government areas in Ogun State, Nigeria. A validated 23-items questionnaire measured on a 69-point rating scale with a Cronbach Alpha scores 0.79 was used for data collection. The mean ±SD age and age at menarche of adolescent girls was 14.92±1.82; 12.73±1.38. The majority of respondents had low scores of perceptions. The educational intervention had an effective change in the level of perception of adolescent schoolgirls between baseline and the 6th-week follow-up, indicating a mean difference of 26.70 (p<0.01) for the peer-led, 26.54(p<0.01) parent-led, 20.16(p<0.01) parent and peer-led and a decrease in mean in the control group (-0.17; p=0.866). The peer-led educational approach had a better impact on adolescent girls’ perception compared to other educational approaches. Hence, this is an indication that peer-education strategies should be utilized for further interventions and in reaching out to adolescents.

The influence of harshness and unpredictability on female sexual development: Addressing gene–environment interplay using a polygenic score

Recent developments in the application life history theory to human development indicate two fundamental dimension of the early environment – harshness and unpredictability – are key regulators life history strategies. Few studies have examined the manner with which these dimensions influence development, though age at menarche (AAM) and age at first sexual intercourse have been proposed as possible mechanisms among women. Data from the Avon Longitudinal Study of Parents and Children (N = 3,645) were used to examine direct and indirect effects of harshness (financial difficulties) and unpredictability (paternal transitions) on lifetime and past year sexual partners during adolescence and young adulthood. Genetic confounding was addressed using an AAM polygenic score (PGS) and potential gene-by-environment interactions were also evaluated using the PGS. Path model results showed only harshness was directly related to AAM. Harshness, unpredictability, and AAM were indirectly related to lifetime and past year sexual partner number via age at first sexual intercourse. The PGS did not account for any of the associations and no significant interactions were detected. Implications of these results for developmental models derived from life history theory are discussed as well as the role of PGSs in gene–environment interplay research.