The article discusses the results of implementation of the laboratory information management system (LIMS) U-LAB, developed by the UralNIIstrom Institute and tested in the regional road sector. The system of quality control of asphalt-concrete road surfaces, road pavement structures and road-building materials in the construction, repair and maintenance of highways is presented, the role of independent laboratory control, engineering and scientifictechnical support, supervision of design decisions is defined. The content and advantages of using the U-LAB LIMS for organizing and improving the efficiency of laboratory quality control of highways and building materials, improving interaction between road management bodies, contractors, design and scientific organizations involved in road works are described. The program interface is shown, the results and technical and economic indicators of the implementation and operation of LIMS in the UralNIIstrom test center in 2020 are presented.