EXPRESS: Distinct abilities associated with matching same identity faces vs. discriminating different faces: Evidence from individual differences in prosopagnosics and controls

Previous face matching studies provide evidence that matching same identity faces (match trials) and discriminating different face identities (non-match trials) rely on distinct processes. For example, instructional studies geared towards improving face matching in applied settings have often found selective improvements in match or non-match trials only. Additionally, a small study found that developmental prosopagnosics (DPs) have specific deficits in making match but not non-match judgments. In the current study, we sought to replicate this finding in DPs and examine how individual differences across DPs and controls in match vs. non-match performance relate to featural vs. holistic processing abilities. 43 DPs and 27 controls matched face images shown from similar front views or with varied lighting or viewpoint. Participants also performed tasks measuring featural (eyes/mouth) and holistic processing (part-whole task). We found that DPs showed worse overall matching performance than controls and that their relative match vs. non-match deficit depended on image variation condition, indicating that DPs do not consistently show match- or non-match-specific deficits. When examining the association between holistic and featural processing abilities and match vs. non-match trials in the entire group of DPs and controls, we found a very clear dissociation: Match trials significantly correlated with eye processing ability (r=.48) but not holistic processing (r=.11), whereas non-match trials significantly correlated with holistic processing (r=.32) but not eye processing (r=.03). This suggests that matching same identity faces relies more on eye processing while discriminating different faces relies more on holistic processing.

Exploring the Mechanism of Pathological Gaming in Adolescents: Focused on the Mediation Paths and Latent Group Comparison

Pathological gaming among adolescents has been reported to hamper the achievement of a balanced life and to threaten the development of social competencies. Despite the increasing social concerns on the adolescent users, however, the mechanism of gaming behavior of adolescents has not been sufficiently examined. This study explored the mechanism of pathological gaming among adolescents from 3-year longitudinal data of 778 Korean adolescent gamers, by analyzing the effects of negative affects (i.e., anxiety, loneliness, and academic stress) on the degree of pathological gaming through the mediation variables (i.e., aggression and self-control) based on the stimulus-organism-response (S-O-R) framework. Latent class analysis (LCA) was used to uncover potential risk groups, and through partial least squares-structural equation modeling (PLS-SEM) analysis, the mediation pathways to pathological gaming were compared between the risk group and the non-risk group. The results highlighted the key role of academic stress on the degree of pathological gaming. In the entire group, academic stress primarily increased pathological gaming through self-control. The mediation path of self-control was the most influential result in the risk group. Aggression was the key mediator between loneliness and pathological gaming in the non-risk group. The theoretical and practical implications of the results were discussed.

The Relationship Between the Distribution of Training Intensity and Performance of Kayak and Canoe Sprinters: A Retrospective Observational Analysis of One Season of Competition

Purpose: To evaluate retrospectively the training intensity distribution (TID) among highly trained canoe sprinters during a single season and to relate TID to changes in performance.Methods: The heart rates during on-water training by 11 German sprint kayakers (7 women, 4 men) and one male canoeist were monitored during preparation periods (PP) 1 and 2, as well as during the period of competition (CP) (total monitoring period: 37 weeks). The zones of training intensity (Z) were defined as Z1 [<80% of peak oxygen consumption (VO2peak)], Z2 (81–87% VO2peak) and Z3 (>87% VO2peak), as determined by 4 × 1,500-m incremental testing on-water. Prior to and after each period, the time required to complete the last 1,500-m stage (all-out) of the incremental test (1,500-m time-trial), velocities associated with 2 and 4 mmol·L−1 blood lactate (v2[BLa], v4[BLa]) and VO2peak were determined.Results: During each period, the mean TID for the entire group was pyramidal (PP1: 84/12/4%, PP2: 80/12/8% and CP: 91/5/4% for Z1, Z2, Z3) and total training time on-water increased from 5.0 ± 0.9 h (PP1) to 6.1 ± 0.9 h (PP2) and 6.5 ± 1.0 h (CP). The individual ranges for Z1, Z2 and Z3 were 61–96, 2–26 and 0–19%. During PP2 VO2peak (25.5 ± 11.4%) markedly increased compared to PP1 and CP and during PP1 v2[bla] (3.6 ± 3.4%) showed greater improvement compared to PP2, but not to CP. All variables related to performance improved as the season progressed, but no other effects were observed. With respect to time-trial performance, the time spent in Z1 (r = 0.66, p = 0.01) and total time in all three zones (r = 0.66, p = 0.01) showed positive correlations, while the time spent in Z2 (r = −0.57, p = 0.04) was negatively correlated.Conclusions: This seasonal analysis of the effects of training revealed extensive inter-individual variability. Overall, TID was pyramidal during the entire period of observation, with a tendency toward improvement in VO2peak, v2[bla], v4[bla] and time-trial performance. During PP2, when the COVID-19 lockdown was in place, the proportion of time spent in Z3 doubled, while that spent in Z1 was lowered; the total time spent training on water increased; these changes may have accentuated the improvement in performance during this period. A further increase in total on-water training time during CP was made possible by reductions in the proportions of time spent in Z2 and Z3, so that more fractions of time was spent in Z1.

P300 Evoked Response Potentials Patterns in Different Complex Concussion Phenotypes

ObjectiveDetermine the utility of P300 Evoked Response Potentials (ERP) voltage patterns in predicting phenotypical sequelae of patients with complex concussions or Persistent Post Concussive Symptoms (PPCS).BackgroundERPs have been used to aid in the diagnosis of multiple neurologic disorders. They have also been recently used in the evaluation of concussions.Design/MethodsA retrospective study of 54 patients, 10–71 year (mean age 29.6 yrs), with PPCS were tested between 6 and 12 weeks post-injury using the standard oddball audio P300 ERP protocol with measures extracted including best central parietal P300 ERP. PPCS Phenotyping was completed in each patient using a standardized post-concussive questionnaire and Rivermead method for 5 primary phenotypes and mixed type.ResultsP300 average Voltage for the entire group was 11.6 mV. Overall, these were significantly lower than age-matched non concussed controls whose average voltage was 16.3 mV (p < 0.0001). Average P300 voltages for each phenotype: Cognition- 14.1 mV, Vestibular- 8.6 mV, Headache- 11.1 mV, Mood- 13.6 mV, Neck Pain- 9.6 mV, Visual- 9.8 mV, Mixed- 6.9 mV, Mixed and Vestibular phenotypes demonstrated the lowest average voltage potentials (6.9 mV and 8.6 mV respectively) which coincided with higher average symptom scores (70.5 and 54.5 respectively). Cognition and Mood demonstrated the highest average voltage potentials (14.1 mV and 13.6 nV respectively), which coincided with lower average symptom scores (40.3 and 48.7, respectively). Mood (13.6 mV) was the lowest average symptom score in the group at 40.3 and Mixed (6.9 mV) was highest at 70.5. Comparing phenotypes against one other, mixed vs mood (p = 0.03), cognition vs vestibular (p = 0.02), and cognition vs mixed (p = 0.009) showed statistical significance.ConclusionsP300 ERPs may help identify persistent abnormal complex concussion neurophysiology. ERPs can also potentially exhibit phenotype specific patterns and be a useful tool in helping differentiate more somatic/physiologic vs mood-based phenotypes. This can ultimately lead in the aid in diagnosis, prognosis, subtyping, and targeted phenotype management.

Level of Cellphone Usage and Academic Performance

This descriptive research paper was conducted to find out the level of cellphone usage and the English academic performance of the AB English students of the Northern Iloilo Polytechnic State College, Estancia, Iloilo. The respondents were the 46 AB English students, 16 of which were the first year and 30 were the fourth year AB English students enrolled in the first semester AY 2018-2019, classified according to sex and year level. The statistical tools used were mean, frequency counts and percentage, t-test, Pearson r. The researcher made questionnaire underwent the validity and reliability testing. Researcher made questionnaire were classified into two parts: Part I, the personal data sheet which include the questions name, sex and year level. Part II has 30 item-cellphone usage questionnaire. It was generally found out that AB English students have always level of cellphone usage. In view of these findings, it can be concluded that the level of cellphone usage of the AB English students when taken as an entire group was always but when classified as to sex, female always used their cellphone while males used their cellphones sometimes. The study also showed that first year AB English students have sometimes level of cellphone usage while the fourth year AB English students always used their cellphones.

Attitudes Toward Artificial Intelligence Among Dermatologists in Morocco: A National Survey

Background Artificial intelligence (AI) is a hot topic, and the use of AI in our day-to-day lives has increased exponentially. AI is becoming increasingly important in dermatology, with studies reporting accuracy matching or exceeding that of dermatologists in the diagnosis of skin lesions from clinical and dermoscopic images. However, little is known about the attitudes of dermatologists in Morocco toward AI. Objective The purpose of this cross-sectional study was to evaluate the attitudes of dermatologists in Morocco toward AI. Methods An online survey was distributed through Google Forms (Google LLC) to dermatologists in Morocco and was open from January to June 2021. Statistical analysis of the data collected was performed using Jamovi software. Any association for which the P value was <.05 was considered statistically significant. Results In total, 183 surveys were completed and analyzed. Overall, 79.8% of respondents were female, and the median age was 35 years (IQR 25-74 years). A total of 30.6% stated that they were not aware of AI, and 34.4% had a basic knowledge of AI technologies. Only 7.7% of the respondents strongly agreed that the human dermatologist will be replaced by AI in the foreseeable future. Of the entire group, 61.8% agreed or strongly agreed that AI will improve dermatology, and 70% thought that AI should be part of medical training. In addition, only 32.2% reported having read publications about AI. Female dermatologists showed more fear pertaining to the use of AI within dermatology (P=.01); this group also suggested that AI has a very strong potential in the detection of skin diseases using dermoscopic images (P=.03). Conclusions Our results demonstrate an overall optimistic attitude toward AI among dermatologists in Morocco. The majority of respondents believed that it will improve diagnostic capabilities. Conflict of Interest None declared.

Armorial Lockplates: A Story of Success in Renaissance Rome

This article was prompted by a gilt bronze lockplate in the Rijksmuseum, originally the decorative fastening of a chest and one of a large group of similar objects. Hardly any other metalwork design was more extensively reproduced in Italian Mannerism. Its success was based on the appealing design and the fact this type of lockplate offered the possibility of integrating coats of arms and thus personalizing a chest. The paper presents new examples not yet listed in Charles Avery’s comprehensive overview (2001), identifies a whole series of clients for these lockplates on the basis of heraldic and genealogical analyses and deduces from this an origin in Rome and a dating of the entire group (previously dated 1540) to the last third of the sixteenth century.It has been generally assumed that the specific function of these objects was to decorate marriage chests. Closer analysis argues against this thesis. The lockplate in the Rijksmuseum is particularly significant in this context. The coats of arms on its lateral cartouches identify the Roman Orazio Ruspoli and his wife Felice Cavalieri (marr. 1594) as the clients for the piece. Surprisingly, however, the crest on the hasp belongs to a family that was not related to this couple. A comparable finding is made for a lockplate in the National Gallery in Washington, which has also been misinterpreted so far. In this case, too, the coats of arms on the plate and on the hasp do not point to a family connection, but to neighbouring and presumably friendly families. The analysis of other examples, such as one in the Palazzo Venezia, confirms that these lockplates and the chests to which they were attached were not exclusively bound to the context of marriage. As travelling chests, which became must-have items for the Roman upper class, they seem to have been open to a variety of functions.

Physical development and physical preparedness monitoring of lyceum students of different ages

In recent years, the health situation in Ukraine has deteriorated. According to statistics, 50% of children have poor health, 75% of children under 14 have chronic diseases, only 10% of school graduates can be called healthy. The overall incidence of children under the age of 14 increased by 16%, at the age of 15-17 - by 18%. Against this background, the level of physical development of children decreases. The current regulation has updated the work on the implementation of monitoring studies in various fields of activity and at different levels, including in the field of physical culture and sports, in order to increase the efficiency of the process of physical education of schoolchildren. Monitoring the physical development of adolescents is a complex information-analytical and prognostically important system that includes monitoring of health and physical development and its assessment, along with analysis at the level of an individual or a social group to predict future health, both for an individual and for the entire group persons united on a territorial basis or the nature of their activities. Such monitoring helps prevent negative trends in physical development in children and adolescents. Purpose: to analyze the results of monitoring the physical development and physical preparedness of students of the Lyceum Materials and methods: The analysis of materials on this issue was carried out based on the results of the implementation of the national educational initiative "Our New School" in accordance with the plan for the modernization of general education [3], according to which in 2019-2020 in secondary schools of Ivano-Frankivsk, the physical development of schoolchildren and schoolgirls was monitored 100 lyceum students 11-17 years old were examined, who were divided into 2 groups according to their academic performance: 1 gr. consisted of 50 lyceum students (35 girls and 15 boys) with high academic performance (average score 4.75), in the composition of 2 gr. it included 50 lyceum students - "lagging behind" (average score 3.5) (25 girls and 25 boys). Results: monitoring showed that, regardless of the group, lyceum students have an average level of physical development (girls - 62.1%, boys - 57.8%). Only 13.8% of girls and 14.4% of boys have a high level of physical development. Almost a quarter of high school students (23.9% of girls and 27.5% of boys) have a low level of physical development, and there are almost 2 times more such students than lyceum students with a high level of physical development. Conclusion: Summarizing the above, it should be noted that when implementing the results of monitoring physical development, there are two main directions: 1. Correction of deviations identified during monitoring in the state of development of physical condition. 2. Using student monitoring as a basis for creating a sports selection system. Based on this, we can conclude that an important component and subject of monitoring is the physical health of lyceum students, mainly in educational institutions, which contributes to monitoring and management decisions on making adjustments to the educational process.

Variation cardiointervalometry in evaluating the efficiency of medical and psychological rehabilitation measures of military services

BACKGROUND: Тhe main tasks of medical and psychological rehabilitation (MPR): accelerated restoration of the functional state and working capacity of military personnel; increase of reserve capabilities; reduction of the influence of risk factors for various diseases; secondary prevention of chronic diseases and prevention of chronization of acute processes; carrying out measures to eliminate and reduce psychopathological syndromes in order to achieve mental adaptation; restoration of professional health, correction of maladaptosis. AIMS: Is to study the informative value of variational cardiointervalometry (VCM) indicators in assessing the effectiveness of MPR of military personnel. MATERIAL AND METHODS: This study was conducted in the branch Clinical Sanatorium Volga of the Federal State Budgetary Institution Privolzhsky of the Ministry of Defense of the Russian Federation during the work of the psychotherapy room with the category of MPR for 12 months. In addition to the regulated volume of diagnostic studies, the Device for psychophysiological testing UPFT-1/30 Psychophysiologist (manufacturer of LLC NPKF Medikom MTD, Russia) was used. One of the research methods is the assessment of the functional state of the heart rhythm by the method of variational cardiointervalometry (VCM) at admission to MPR and before discharge (also referred to in the literature as heart rate variability, HRV). The study was conducted with 116 servicemen undergoing MPR for fatigue of 12 degrees for 10 days. Representatives of the Strategic Missile Forces (RVSN) ― 34 people; aerospace forces (VKS) ― 32 people; ground forces (SV) ― 50 people. The data is processed in StatSoft Statistica 10 Russian Portable 10.0.1011.0 x86. RESULTS: The average values for the entire group (116 servicemen): at admission and before discharge IN (stress index) increased statistically significantly from 284.5 to 359.7 cu; VLF-decreased from 21.1% to 16.0%; LF/HF (vagosympathetic interaction index) ― from 2.7 to 4.0 cu; Centralization index ― from 3.8 to 5.1 cu; PARS (indicator of adaptation of regulatory systems) ― from 4.6 to 5.3 cu. The result is a pronounced tension of regulatory systems, active mobilization of protective mechanisms, increased activity of the sympatho-adrenal system and the pituitary-adrenal system. CONCLUSION: VCM (HRV) is one of the practical informative methods. RVSN: an increase in the voltage of regulatory systems as a reaction to physical exertion, a post-loading energy-deficient state, the index of vagosympathetic interaction has shifted to the parameters of the norm.VCS: an increase in the voltage of regulatory systems, an increase in the activation of the sympathetic nervous system, an active mobilization of protective mechanisms. SV: a tendency to reduce the voltage of regulatory systems, a post-loading energy-deficient state, a balanced state of the autonomic nervous system (VNS). A delayed training effect is likely, changes occur in the late phases of recovery, after the end of the rehabilitation period.

Prognostic Risk Model and Tumor Immune Environment Modulation of m5C-Related LncRNAs in Pancreatic Ductal Adenocarcinoma

RNA methylation modification is a key process in epigenetics that regulates posttranscriptional gene expression. With advances in next-generation sequencing technology, 5-methylcytosine (m5C) modification has also been found in multiple RNAs. Long non-coding RNAs (lncRNAs) were proved to have a key role in cancer progression and closely related to the tumor immune microenvironment. Thus, based on the PDAC patients’ clinical information and genetic transcriptome data from the TCGA database, we performed a detailed bioinformatic analysis to establish a m5C-related lncRNA prognostic risk model for PDAC patients and discovered the relationship between the risk model and PDAC immune microenvironment. Pearson correlation coefficient analysis was applied to conduct a m5C regulatory gene and m5C-related lncRNA co-expression network. Expression of m5C-related lncRNAs screened by univariate regression analysis with prognostic value showed a significant difference between pancreatic cancer and normal tissues. The least absolute shrinkage and selection operator (LASSO) Cox regression method was applied to determine an 8-m5C-related lncRNA prognostic risk model. We used principal component analysis to indicate that the risk model could distinguish all the samples clearly. The clinical nomogram also accurately predicted 1-, 1.5-, 2-, and 3-year survival time among PDAC patients. Additionally, this risk model was validated in the entire group and sub-test groups using KM analysis and ROC analysis. Combined with the clinical characteristics, the risk score was found to be an independent factor for predicting the survival of PDAC patients. Furthermore, the association between the risk model and tumor immune microenvironment was evaluated via the ESTIMATE R package and CIBERSORT method. Consequently, the results indicated that immune cells were associated with m5C-related lncRNA risk model scores and had different distribution in the high- and low-risk groups. Based on all these analyses, the m5C-related lncRNA risk model could be a reliable prognostic tool and therapeutic target for PDAC patients.