scholarly journals Plasma expanders for people with cirrhosis and large ascites treated with abdominal paracentesis

Author(s):  
Rosa G Simonetti ◽  
Giovanni Perricone ◽  
Dimitrinka Nikolova ◽  
Goran Bjelakovic ◽  
Christian Gluud
1952 ◽  
Vol 55 (3) ◽  
pp. 496-503 ◽  
Author(s):  
Harry M. Vars ◽  
William M. Parkins ◽  
Joseph H. Perlmutt
Keyword(s):  

1982 ◽  
Vol 4 (1) ◽  
pp. 27-27

A reader commented:"In the October issue of PIR(3:121, 1981), in "Necrotizing Entercolitis" Burg and Polin recommend partial exchange transfusion for high hematocrit, using normal saline. I was taught to use fresh frozen plasma or albumin for partial exchanges. What are the advantages, if any, of isotonic saline over plasma or albumin?" Drs Burg and Polin reply: "Although, theoretical arguments can be made for use of fresh frozen plasma to reduce the hematocrit, either saline, synthetic plasma expanders, or 5% albumin would be suitable. Much of the albumin given in plasma or synthetic solutions quickly leaks out of the newborn infant's intravascular compartment. The purpose of a partial exchange transfusion in neonatal polycythemia is to lower the hematocrit and lessen the hyperviscosity; it is not to replace coagulation or immune factors or remove toxins. Saline would be just as satisfactory as plasma for this purpose."


2021 ◽  
Vol 39 (28_suppl) ◽  
pp. 63-63
Author(s):  
Kim Hua Lee

63 Background: Ascites is a common complication of cancer. Symptomatic ascites contributes to cancer-related morbidity and is distressing for patients (pts). Therapeutic abdominal paracentesis (TAP) provides symptom relief but requires specialized procedural knowledge and is usually performed in the inpatient setting with several days of hospitalization. Additionally, high hospital bed occupancy during the COVID-19 pandemic prevented timely admission for TAP. An Advanced Practice Nurse (APN)-led ambulatory TAP service was introduced at our center, with the aim of improving access to TAP and reducing hospital bed occupancy. Methods: A multidisciplinary team developed workflows and safety guidelines for TAP to enable right-siting of pts in a cancer day care unit. Pts were scheduled for radiologically guided insertion of abdominal drains in the morning before 10am to allow adequate time for drainage. Pre-procedure clinical examination and safety checks were performed by APNs in the day unit. Following the procedure, abdominal fluid was drained with concurrent administration of 20% IV albumin. Drains were removed by the APN and pts were examined before discharge on the same day. Data for all cancer pts requiring TAP in the day unit and hospital from 1 Jan to 30 Nov 2020 were extracted from the electronic medical record system. The primary outcome was length-of-stay (LOS). The primary safety outcome was adverse events in the day unit. Continuous data were compared using the t-test. Data analysis was done in SPSS version 22. Results: The number of TAPs performed in the day unit and general ward requiring hospitalization were 102 and 133, respectively. There was a significant reduction in average LOS with TAPs performed in the day unit vs. hospitalization (1.48 vs. 5.82 days, p<0.001) (Table). The mean difference was 4.34 (95% confidence interval 3.33 - 5.34) days saved per pt, or a saving of 443 inpatient bed days. The TAP day unit service encountered 10 adverse events (AEs) requiring admission to the ward for continued drainage. AEs were borderline baseline blood pressure, pt frailty and inability to care for an indwelling catheter. There were no infective or bleeding complications. The majority of TAPs (86.8%) were performed in one day, with the remainder over 2-days with the abdominal drain left in-situ and reattendance at the day unit the next day for further drainage. Differences in average length-of-stay with TAP in the hospital vs. day unit. Conclusions: An APN-led ambulatory abdominal paracentesis service is a safe alternative to inpatient paracentesis. Optimal utilization of a day unit enabled reduced LOS for pts with advanced cancer. This reduction in LOS was critical during a pandemic where bed demand was high. This was possible from advanced scheduling and control over the day unit capacity.[Table: see text]


2017 ◽  
pp. bcr2016216077 ◽  
Author(s):  
Michael Patrick Turner ◽  
Sophie Arndtz ◽  
George MacFaul

Author(s):  
Behnam Kian ◽  
Arash Teimouri

Inferior epigastric artery pseudoaneurysm is a rare complication following abdominal wall procedures near the artery. This is a case of Inferior epigastric artery pseudoaneurysm after therapeutic paracentesis for large volume ascites caused by chronic kidney failure. The patient was operated on, and the artery was ligated.


2021 ◽  
Author(s):  
Vishal Sharma ◽  
Daya Krishna Jha ◽  
Manish Rohilla ◽  
Chandan K Das ◽  
Harjeet Singh ◽  
...  

The sensitivity of single abdominal paracentesis for diagnosis of peritoneal carcinomatosis in patients with malignant ascites is 40–70%. Tumor cells shed from the peritoneum settle preferentially in certain recesses of the peritoneum. We aim to compare the standard technique of abdominal paracentesis versus a rollover technique in a randomized crossover study to assess the cytological yield in patients suspected to have peritoneal carcinomatosis. Each patient will serve as their own control and the outcome assessor (cytopathologist) will be blinded to the method of paracentesis performed. The primary objective will be to compare the tumor cell positivity between the standard paracentesis group and the rollover group among enrolled patients. Clinical Trial registration: CTRI/2020/06/025887 and NCT04232384 .


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