Click chemistry based regioselective one‐pot synthesis of coumarin‐3‐yl‐methyl‐1,2,3‐triazolyl‐1,2,4‐triazol‐3(4 H )‐ones as newer potent antitubercular agents

2019 ◽  
Vol 352 (10) ◽  
pp. 1900013 ◽  
Author(s):  
Shilpa M. Somagond ◽  
Ravindra R. Kamble ◽  
Praveen K. Bayannavar ◽  
Saba Kauser J. Shaikh ◽  
Shrinivas D. Joshi ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Antitubercular Agents ◽  
One Pot ◽  
One Pot Synthesis

Cu(ii) PBS-bridged PMOs catalyzed one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles in water through click chemistry

RSC Advances ◽  
2014 ◽  
Vol 4 (56) ◽  
pp. 29772-29781 ◽  
Author(s):  
Avvari N. Prasad ◽  
Benjaram M. Reddy ◽  
Eun-Young Jeong ◽  
Sang-Eon Park
Keyword(s):  
Click Chemistry ◽  
Heterogeneous Catalyst ◽  
Efficient Synthesis ◽  
One Pot ◽  
One Pot Synthesis

Efficient synthesis of 1,4-disubstituted 1,2,3-triazoles using Cu(ii)-PBS-HPMO as a heterogeneous catalyst.

One-pot synthesis of bio-functionally water-soluble POSS derivatives via efficient click chemistry methodology

2019 ◽  
Vol 140 ◽  
pp. 103-110 ◽  
Author(s):  
Jifeng Zhang ◽  
Zhanpeng Luo ◽  
Wanjie Wang ◽  
Yanyu Yang ◽  
Dawei Li ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Water Soluble ◽  
One Pot ◽  
One Pot Synthesis

One-pot synthesis of new triazole-sucrose derivatives via click chemistry and evaluation of their antitubercular activity

2016 ◽  
Vol 22 (4) ◽  
Author(s):  
Khaoula Hajlaoui ◽  
Ahlem Guesmi ◽  
Naoufel Ben Hamadi ◽  
Moncef Msaddek
Keyword(s):  
Click Chemistry ◽  
Copper Nanoparticles ◽  
Antitubercular Activity ◽  
Antimycobacterial Activity ◽  
Dipolar Cycloaddition ◽  
One Pot ◽  
Effective Catalyst ◽  
One Pot Synthesis

AbstractReadily prepared copper nanoparticles are an effective catalyst for 1,3-dipolar cycloaddition of carbohydrate azide and a variety of alkynes that furnishes the corresponding 1,2,3-triazole-sucrose derivatives in excellent yields. Products were screened for their antimycobacterial activity against

One-pot synthesis of bicyclic polystyrene by combination of ATRP and click chemistry

2016 ◽  
Vol 24 (10) ◽  
pp. 856-861 ◽  
Author(s):  
Hyerin Choi ◽  
Taeheon Lee ◽  
Jonghwa Jeong ◽  
Jihwa Ye ◽  
Heung Bae Jeon ◽  
...  
Keyword(s):  
Click Chemistry ◽  
One Pot ◽  
One Pot Synthesis

scholarly journals AN EFFICIENT THREE COMPONENT ONE-POT SYNTHESIS OF -1,2,3,4-TETRAHYDRO-4-OXO- 6-(5-SUBSTITUTED 2-PHENYL-1H-INDOL-3-YL)-2-THIOXOPYRIMIDINE-5-CARBONITRILE AS ANTIMICROBIAL AND ANTITUBERCULAR AGENTS

2021 ◽  
pp. 94-97
Author(s):  
PRABHAKER WALMIK
Keyword(s):  
Spectral Data ◽  
13C Nmr ◽  
Antitubercular Agents ◽  
Mass Spectral Data ◽  
One Pot ◽  
1H And 13C Nmr ◽  
Spectral Techniques ◽  
Mass Spectral ◽  
One Pot Synthesis

Objective: The objective of the study was to synthesis of 1,2,3,4-tetrahydro-4-oxo-6-(5-substituted 2-phenyl-1H-indol-3-yl)-2-thioxopyrimidine-5- carbonitrile derivatives (4a-c). Methods: The structures of all these unknown compounds have been confirmed with the help of physical and spectral techniques such as IR, 1H, and 13C NMR and mass spectral data and these newly synthesized compounds were evaluated for in-vitro antimicrobial and antitubercular activities. Results: Screening studies have demonstrated that the newly synthesized compound 4a exhibited promising antimicrobial and antitubercular properties. Conclusion: The final results revealed that compound 4a exhibited promising antimicrobial and antitubercular properties when compared to the standard drugs.

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