Highly Enantioselective Michael Addition of Cyclic Diketones to β,γ-Unsaturated α-Keto Esters Catalyzed by Squaramide Organocatalyst

A new tertiary amine-squaramide organocatalyst has been developed and applied to the asymmetric Michael addition of cyclic diketones to β,γ-unsaturated α-keto esters. The catalyst system performed well with a low catalyst loading of 1 mol% under mild reaction conditions. A series of synthetically and pharmaceutically useful chiral bicyclic compounds were obtained in high yields (up to 97%) with excellent enantioselectivities (up to 99 % ee). Furthermore, this catalytic system can be used efficiently in large-scale reactions with the yields and enantioselectivities being maintained.

Heterogeneous Iron Catalyst Fe/SBA-15 towards sp3 C-O bond activation in the absence of base and additive

A heterogeneous iron-catalyzed (8wt%Fe/SBA-15) mediated direct alkylation of benzyl alcohol with aryl boronic acid in the absence of base and additive via C-O bond activation is demonstrated. This catalyst system led to an efficient Friedel-crafts alkylation reaction. The acidic site in the catalyst system had been confirmed by NH3-TPD, which shows the presence of three different acidic sites viz., weak, moderated, and strong acid sites. The catalyst showed five times recyclable ability.

Rhodium-catalyzed regioselective addition of thioacids to terminal allenes: enantioselective access to branched allylic thioesters

Regioselective and enantioselective addition of thioacids to terminal allenes is reported employing a rhodium(i)/DIOP catalyst system. Complete catalyst control of diastereoselectivity was achieved upon addition of chiral amino thioacids to allenes.

Catalytic and mechanistic studies of a highly active and E-selective Co(II) PNNH pincer catalyst system for transfer-semihydrogenation of internal alkynes

Herein we report the application of a Co(II) PNNH pincer catalyst system (PNNH = 2-(5-(t-butyl)-1H-pyrazol-3-yl)-6-(dialkylphosphinomethyl)pyridine) for the highly E-selective transfer semihydrogenation of internal diaryl alkynes using methanol and ammonia borane...

Doped Ceria Catalyst System: Catalyzing Carbon Monoxide Transformation (A-Review)

As ceria chemistry broadens, it is needed to generalize the behavior of ceria surfaces towards molecules for carrying out a reaction. The endowing capacity of mobile oxygen due to rapid redox switching between Ce+4/Ce+3 is a key point for ceria containing surfaces. Herein we have presented a review which is broadly divided into two parts. First part focuses on surface property as how electronic structure, vacancy and surface energy would be modified after interaction of ceria with dopant (noble metal, metal of variable oxidation state, higher valent metal and lower valent metal). The second part focuses on catalysis as how the doped ceria surface influences the carbon monoxide transformations (CO oxidation, CO and H2O reaction, CO and NO reaction, CO and H2 reaction). This through study will be helpful to predict the ceria surface for a designed reaction.

Heterogeneous Iron Catalyst Fe/SBA-15 towards sp3 C-O bond activation in the absence of base and additive

A heterogeneous iron-catalyzed (8wt%Fe/SBA-15) mediated direct alkylation of benzyl alcohol with aryl boronic acid in the absence of base and additive via C-O bond activation is demonstrated. This catalyst system led to an efficient Friedel-crafts alkylation reaction. The acidic site in the catalyst system had been confirmed by NH3-TPD, which shows the presence of three different acidic sites viz., weak, moderated, and strong acid sites. The catalyst showed five times recyclable ability.

STUDY OF THE PROCESS OF HYDRATION OF MESITYL OXIDE IN THE PRESENCE OF NANOCATALYZERS

The process of mesityl oxide hydrogenation in the presence of a nickel catalyst prepared by impregnating a support with an aqueous solution of the corresponding salt in a displacement reactor in a gas-liquid-solid catalyst system has been studied. It has been established that the use of the catalyst used in the work makes it possible to selectively obtain methyl isobutyl ketone with complete conversion of mesityl oxide in the temperature range 70-100 ºС.