scholarly journals The Impact of COVID‐19 Pandemic on Prevalence of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes: A Single‐Centre Study in Central Pennsylvania

2021 ◽  
Author(s):  
Kaleb T. Bogale ◽  
Valerie Urban ◽  
Eric Schaefer ◽  
Kanthi Bangalore Krishna
Keyword(s):  
Type 1 Diabetes ◽  
Diabetic Ketoacidosis ◽  
Single Centre ◽  
Centre Study ◽  
Central Pennsylvania ◽  
Single Centre Study ◽  
The Impact

Abstract #1002088: Correlation between Obesity and Type 1 diabetes mellitus (DM1): A Single Centre Study

2021 ◽  
Vol 27 (6) ◽  
pp. S41
Author(s):  
Dinesh Sharma ◽  
Rahul Ramchandani ◽  
Divyansh Mathur ◽  
Abhilasha Mangal ◽  
Akhil Agrawal ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Single Centre ◽  
Centre Study ◽  
Single Centre Study

Revisiting cytomegalovirus serostatus and replication as risk factors for inferior long-term outcomes in the current era of renal transplantation

2020 ◽  
Vol 35 (2) ◽  
pp. 346-356
Author(s):  
Nicole Bischof ◽  
Caroline Wehmeier ◽  
Michael Dickenmann ◽  
Patricia Hirt-Minkowski ◽  
Patrizia Amico ◽  
...  
Keyword(s):  
Risk Factors ◽  
Renal Transplantation ◽  
Patient Survival ◽  
Long Term Outcomes ◽  
Single Centre ◽  
Centre Study ◽  
Single Centre Study ◽  
Cmv Disease ◽  
The Impact

Abstract Background Cytomegalovirus (CMV) serostatus and CMV replication are considered as risk factors for inferior graft and patient survival after renal transplantation, but long-term outcome data are limited. The aim of this retrospective single-centre study was to investigate the impact of CMV serostatus and CMV replication/disease on long-term outcomes in a well-defined cohort managed by a standardized CMV prevention/treatment protocol. Methods We investigated 599 consecutive kidney transplantations having a CMV prevention protocol consisting of either prophylaxis (D+/R− and R+ with ATG induction) or screening/deferred therapy (R+ without ATG induction). Patients were grouped according to CMV serostatus [high risk (D+/R−): n = 122; intermediate risk (R+): n = 306; low risk (D−/R−): n = 171] and occurrence of CMV replication/disease (no CMV replication: n = 419; asymptomatic CMV replication: n = 110; CMV syndrome: n = 39; tissue-invasive CMV disease: n = 31). The median follow-up time was 6.5 years. Results Graft and patient survival were not different among the three CMV serostatus groups as well as the four CMV replication/disease groups (P ≥ 0.44). Eighty-seven patients died, 17 due to infections (21%), but none was attributable to CMV. The overall hospitalization incidence for CMV-related infection was 3% (17/599 patients). The incidence of clinical and (sub)clinical rejection was similar among the groups (P ≥ 0.17). In a multivariate Cox proportional hazard model, neither CMV serostatus, nor CMV replication, nor CMV disease were independent predictors for patient death or graft failure, respectively. Conclusions This retrospective single-centre study suggests that the negative impact of CMV infection on long-term patient and allograft survival as well as on allograft rejection can be largely eliminated with current diagnostic/therapeutic management.

scholarly journals DIABETIC KETOACIDOSIS AS THE INITIAL PRESENTATION OF TYPE 1 DIABETES IN CHILDREN AND ADOLESCENTS: EPIDEMIOLOGICAL STUDY IN SOUTHERN BRAZIL

2020 ◽  
Vol 38 ◽  
Author(s):  
Leonardo Calil Vicente Franco de Souza ◽  
Gabriela de Carvalho Kraemer ◽  
Adriana Koliski ◽  
José Eduardo Carreiro ◽  
Mônica Nunes Lima Cat ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Children And Adolescents ◽  
Diabetic Ketoacidosis ◽  
University Hospital ◽  
Pediatric Endocrinology ◽  
Altered Level ◽  
Duration Of Symptoms ◽  
The Impact

ABSTRACT Objective: To analyze the variables associated with the presence of diabetic ketoacidosis in type 1 diabetes mellitus (T1DM) diagnosis and its impact on the progression of the disease. Methods: We reviewed the records of 274 children and adolescents under 15 years, followed in a Pediatric Endocrinology clinic of a university hospital in Curitiba-PR. They had their first appointment between January 2005 and April 2015. Results: Most patients received their T1DM diagnosis during a diabetic ketoacidosis episode. The associated factors were: lower age and greater number of visits to a physician’s office prior to diagnosis; diabetic ketoacidosis was less frequent in patients who had siblings with T1DM and those diagnosed at the first appointment. Nausea and vomiting, abdominal pain, tachydyspnea, and altered level of consciousness were more common in the diabetic ketoacidosis group. There was no association with socioeconomic status, duration of symptoms before diagnosis, and length of the honeymoon period. Conclusions: Prospective studies are necessary to better define the impact of these factors on diagnosis and disease control. Campaigns to raise awareness among health professionals and the general population are essential to promote early diagnosis and proper treatment of diabetes mellitus in children and adolescents.

scholarly journals The impact of FSH receptor polymorphism on time-to-pregnancy: a cross-sectional single-centre study

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Birute Zilaitiene ◽  
Marius Dirzauskas ◽  
Rasa Verkauskiene ◽  
Rytas Ostrauskas ◽  
Joerg Gromoll ◽  
...  
Keyword(s):  
Fsh Receptor ◽  
Single Centre ◽  
Time To Pregnancy ◽  
Cross Sectional ◽  
Centre Study ◽  
Single Centre Study ◽  
The Impact ◽  
Fsh Receptor Polymorphism ◽  
Receptor Polymorphism

scholarly journals The Impact of Body Morphology on Rotation on Chest Radiograph: A Single Centre Study

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Ogoke AO ◽  
Ugwu AC ◽  
Ugwuanyi DC ◽  
Ohagwu CC ◽  
Ogolodom MP ◽  
...  
Keyword(s):  
Chest Radiograph ◽  
Single Centre ◽  
Body Morphology ◽  
Centre Study ◽  
Single Centre Study ◽  
The Impact
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