Determination of lipid–water partition coefficient of neutral and ionic drugs by liposome electrokinetic chromatography

2021 ◽  
Author(s):  
Hui Jiang ◽  
Hao Zhang ◽  
Shi‐Jun Yin ◽  
Min Lu ◽  
Xu Wang ◽  
...  
Keyword(s):  
Partition Coefficient ◽  
Electrokinetic Chromatography ◽  
Water Partition Coefficient

Determination of Ionization Constant (pKa) and Octanol–Water Partition Coefficient (Log P) of Cyclopiazonic Acid

2005 ◽  
Vol 88 (5) ◽  
pp. 1367-1370 ◽  
Author(s):  
Victor S Sobolev
Keyword(s):  
Partition Coefficient ◽  
Potentiometric Titration ◽  
Ionization Constant ◽  
Cyclopiazonic Acid ◽  
Log P ◽  
Experimental Conditions ◽  
Water Partition Coefficient

Abstract The ionization constant (pKa) and the octanol–water partition coefficient (log P) of the important mycotoxin cyclopiazonic acid (CPA) were determined by means of potentiometric titration, and the lipophilicity profile (log D) was calculated. Under the experimental conditions, pKa of CPA = 2.97 ± 0.09, log P = 3.83 ± 0.10, and log D at pH 7.4 = −0.58.

Determination of acid base balance and oil water partition coefficient of an atopy patch test of levofloxacin

2008 ◽  
Vol 62 (2) ◽  
pp. 136-138 ◽  
Author(s):  
Julien Lecordier ◽  
Jean-Jacques Lahet ◽  
Carol Courderot-Masuyer ◽  
Etienne Beaudoin ◽  
Bernard Chaillot
Keyword(s):  
Partition Coefficient ◽  
Patch Test ◽  
Atopy Patch Test ◽  
Acid Base Balance ◽  
Acid Base ◽  
Water Partition Coefficient ◽  
Base Balance ◽  
Oil Water

Determination of n-octanol/water partition coefficient for DDT-related compounds by RP-HPLC with a novel dual-point retention time correction

Chemosphere ◽  
2011 ◽  
Vol 83 (2) ◽  
pp. 131-136 ◽  
Author(s):  
Shu-ying Han ◽  
Jun-qin Qiao ◽  
Yun-yang Zhang ◽  
Li-li Yang ◽  
Hong-zhen Lian ◽  
...  
Keyword(s):  
Partition Coefficient ◽  
Retention Time ◽  
Rp Hplc ◽  
Water Partition Coefficient ◽  
Time Correction ◽  
Related Compounds

Chromatographic methods in determination of the soil–water partition coefficient

2016 ◽  
Vol 39 (5-6) ◽  
pp. 249-256 ◽  
Author(s):  
Filip Andrić ◽  
Sandra Šegan ◽  
Živoslav Tešić ◽  
Dušanka Milojković-Opsenica
Keyword(s):  
Partition Coefficient ◽  
Soil Water ◽  
Chromatographic Methods ◽  
Water Partition Coefficient
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