scholarly journals Altered resting‐state functional network connectivity in profound sensorineural hearing loss infants within an early sensitive period: A group ICA study

2021 ◽  
Author(s):  
Shanshan Wang ◽  
Boyu Chen ◽  
Yalian Yu ◽  
Huaguang Yang ◽  
Wenzhuo Cui ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Resting State ◽  
Network Connectivity ◽  
Sensorineural Hearing ◽  
Functional Network ◽  
Sensitive Period ◽  
Functional Network Connectivity ◽  
Group Ica

scholarly journals Alterations of Regional Homogeneity in Children With Congenital Sensorineural Hearing Loss: A Resting-State fMRI Study

2021 ◽  
Vol 15 ◽  
Author(s):  
Pingping Guo ◽  
Siyuan Lang ◽  
Muliang Jiang ◽  
Yifeng Wang ◽  
Zisan Zeng ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Prefrontal Cortex ◽  
Sensorineural Hearing Loss ◽  
Resting State ◽  
Regional Homogeneity ◽  
Sensorineural Hearing ◽  
Parahippocampal Gyrus ◽  
Control Group ◽  
Precentral Gyrus ◽  
Healthy Controls

Background: Brain functional alterations have been observed in children with congenital sensorineural hearing loss (CSNHL). The purpose of this study was to assess the alterations of regional homogeneity in children with CSNHL.Methods: Forty-five children with CSNHL and 20 healthy controls were enrolled into this study. Brain resting-state functional MRI (rs-fMRI) for regional homogeneity including the Kendall coefficient consistency (KCC-ReHo) and the coherence-based parameter (Cohe-ReHo) was analyzed and compared between the two groups, i.e., the CSNHL group and the healthy control group.Results: Compared to the healthy controls, children with CSNHL showed increased Cohe-ReHo values in left calcarine and decreased values in bilateral ventrolateral prefrontal cortex (VLPFC) and right dorsolateral prefrontal cortex (DLPFC). Children with CSNHL also had increased KCC-ReHo values in the left calcarine, cuneus, precentral gyrus, and right superior parietal lobule (SPL) and decreased values in the left VLPFC and right DLPFC. Correlations were detected between the ReHo values and age of the children with CSNHL. There were positive correlations between ReHo values in the pre-cuneus/pre-frontal cortex and age (p < 0.05). There were negative correlations between ReHo values in bilateral temporal lobes, fusiform gyrus, parahippocampal gyrus and precentral gyrus, and age (p < 0.05).Conclusion: Children with CSNHL had RoHo alterations in the auditory, visual, motor, and other related brain cortices as compared to the healthy controls with normal hearing. There were significant correlations between ReHo values and age in brain regions involved in information integration and processing. Our study showed promising data using rs-fMRI ReHo parameters to assess brain functional alterations in children with CSNHL.

Modafinil Modulates Resting-State Functional Network Connectivity and Cognitive Control in Alcohol-Dependent Patients

2013 ◽  
Vol 73 (8) ◽  
pp. 789-795 ◽  
Author(s):  
Lianne Schmaal ◽  
Anna E. Goudriaan ◽  
Leen Joos ◽  
Anne Maren Krüse ◽  
Geert Dom ◽  
...  
Keyword(s):  
Cognitive Control ◽  
Resting State ◽  
Network Connectivity ◽  
Functional Network ◽  
Functional Network Connectivity ◽  
Alcohol Dependent
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