scholarly journals Expression of the putative tumor suppressor genePTPN13/PTPL1is an independent prognostic marker for overall survival in breast cancer

2009 ◽  
Vol 124 (3) ◽  
pp. 638-643 ◽  
Author(s):  
Françoise Révillion ◽  
Carole Puech ◽  
Fanja Rabenoelina ◽  
Dany Chalbos ◽  
Jean-Philippe Peyrat ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Overall Survival ◽  
Tumor Suppressor ◽  
Prognostic Marker ◽  
Independent Prognostic Marker ◽  
Putative Tumor Suppressor

Elevated Bcl-2 expression as an independent prognostic marker for decreased overall survival in patients with triple-negative breast cancer

2018 ◽  
Vol 92 ◽  
pp. S125
Author(s):  
L. Beketic Oreskovic ◽  
P. Ozretic ◽  
I. Alvir ◽  
Z. Vujaskovic ◽  
Z. Rendic-Miocevic ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Overall Survival ◽  
Prognostic Marker ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Independent Prognostic Marker

scholarly journals EP3 Is an Independent Prognostic Marker Only for Unifocal Breast Cancer Cases

2020 ◽  
Vol 21 (12) ◽  
pp. 4418
Author(s):  
Alaleh Zati Zehni ◽  
Udo Jeschke ◽  
Anna Hester ◽  
Thomas Kolben ◽  
Nina Ditsch ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Overall Survival ◽  
Prognostic Marker ◽  
Disease Free Survival ◽  
Receptor Expression ◽  
Clinicopathological Parameters ◽  
Prognostic Impact ◽  
Patient Cohort ◽  
Independent Prognostic Marker ◽  
Ep3 Receptor

The aim of this study was to evaluate the prognostic impact of prostaglandin E2 receptor 3 (EP3) receptor expression might have on the two different breast cancer entities: multifocal/multicentric versus unifocal. As the prognosis determining aspects, we investigated the overall- and disease-free survival by uni-and multivariate analysis. To underline the study’s conclusion, we additionally considered the histopathological grading and the tumor node metastasis (TNM) staging system. A retrospective statistical analysis was performed on survival related events in a series of 289 sporadic breast cancer (BC) patients treated at the Department of Obstetrics and Gynecology at the Ludwig–Maximillian’s University in Munich between 2000 and 2002. The EP3 receptor expression was analyzed by immunohistochemistry and showed to have a significantly positive association with breast cancer prognosis for both entities, although with major differences. Patients with unifocal BC with EP3 receptor expression showed a significant improved overall survival, in contrast to the patient cohort with multifocal/multicentric BC. In this group, EP3 expression revealed its positive impact merely five years after initial diagnosis. Underlining the positive influence of EP3 as a positive prognosticator notably for unifocal breast cancer, only this patient cohort showed favorable outcomes in staging and grading. Especially EP3 expression in unifocal breast cancer was identified as an independent prognostic marker for the overall survival, when adjusted for age, grading, and staging. Altogether, our results strengthen the need to further investigate the behavior of EP3 in breast cancer and understand why markers linked to inflammation show different effects on prognosis and clinicopathological parameters on each focality type.

scholarly journals 17β-Hydroxysteroid Dehydrogenase Type 1 Is an Independent Prognostic Marker in Breast Cancer

2004 ◽  
Vol 64 (20) ◽  
pp. 7604-7609 ◽  
Author(s):  
Olayiwola O. Oduwole ◽  
Yan Li ◽  
Veli V. Isomaa ◽  
Anne Mäntyniemi ◽  
Anitta E. Pulkka ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Marker ◽  
Hydroxysteroid Dehydrogenase ◽  
Independent Prognostic Marker

scholarly journals Telomerase is an independent prognostic marker of overall survival in patients with colorectal cancer

2013 ◽  
Vol 108 (2) ◽  
pp. 278-284 ◽  
Author(s):  
R Bertorelle ◽  
M Briarava ◽  
E Rampazzo ◽  
L Biasini ◽  
M Agostini ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Overall Survival ◽  
Prognostic Marker ◽  
Independent Prognostic Marker

FOXA1 is an independent prognostic marker for ER-positive breast cancer

2011 ◽  
Vol 131 (3) ◽  
pp. 881-890 ◽  
Author(s):  
Rutika J. Mehta ◽  
Rohit K. Jain ◽  
Samuel Leung ◽  
Jennifer Choo ◽  
Torsten Nielsen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Marker ◽  
Independent Prognostic Marker ◽  
Er Positive ◽  
Positive Breast Cancer
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