Facile One-Pot Conversion of Petroleum Asphaltene to High Quality Green Fluorescent Graphene Quantum Dots and Their Application in Cell Imaging

Graphene Quantum Dots (GQDs) have been prepared by oxidationhydrothermal reaction, using ball-milling graphite as the starting materials. The prepared GQDs are endowed with excellent luminescence properties, with the optimum emission of 320nm. Blue photoluminescent emitted from the GQDs under ultraviolet light. The GQDs are ~3nm in width and 0.5~2 nm in thickness, revealed by high-resolution transmission electron microscopy and atomic force microscopy. In addition, Fourier transform infrared spectrum evidences the existence of carbonyl and hydroxyl groups, meaning GQDs can be dispersed in water easily and used in cellar imaging, and blue area inside L929 cells were clearly observed under the fluorescence microscope. Both low price of raw material and simple prepared method contribute to the high quality GQDs widespread application in future.

Download Full-text

Microwave assisted one-pot synthesis of graphene quantum dots as highly sensitive fluorescent probes for detection of iron ions and pH value

Talanta ◽

10.1016/j.talanta.2015.12.015 ◽

2016 ◽

Vol 150 ◽

pp. 54-60 ◽

Cited By ~ 84

Author(s):

Chunfang Zhang ◽

Yanyan Cui ◽

Li Song ◽

Xiangfeng Liu ◽

Zhongbo Hu

Keyword(s):

Quantum Dots ◽

Fluorescent Probes ◽

Ph Value ◽

Graphene Quantum Dots ◽

Iron Ions ◽

One Pot ◽

Microwave Assisted ◽

One Pot Synthesis ◽

Highly Sensitive

Download Full-text

Chlorine Modulation Fluorescent Performance of Seaweed-Derived Graphene Quantum Dots for Long-Wavelength Excitation Cell-Imaging Application

Molecules ◽

10.3390/molecules26164994 ◽

2021 ◽

Vol 26 (16) ◽

pp. 4994

Author(s):

Weitao Li ◽

Ningjia Jiang ◽

Bin Wu ◽

Yuan Liu ◽

Luoman Zhang ◽

...

Keyword(s):

Quantum Dots ◽

Cell Imaging ◽

Graphene Quantum Dots ◽

Toxic Metal ◽

Disease Diagnosis ◽

Excitation Wavelength ◽

Chlorine Atoms ◽

Long Wavelength ◽

Imaging Application ◽

Preliminary Application

Biological imaging is an essential means of disease diagnosis. However, semiconductor quantum dots that are used in bioimaging applications comprise toxic metal elements that are nonbiodegradable, causing serious environmental problems. Herein, we developed a novel ecofriendly solvothermal method that uses ethanol as a solvent and doping with chlorine atoms to prepare highly fluorescent graphene quantum dots (GQDs) from seaweed. The GQDs doped with chlorine atoms exhibit high-intensity white fluorescence. Thus, their preliminary application in bioimaging has been confirmed. In addition, clear cell imaging could be performed at an excitation wavelength of 633 nm.

Download Full-text

Solid-phase synthesis of graphene quantum dots from the food additive citric acid under microwave irradiation and their use in live-cell imaging

Luminescence ◽

10.1002/bio.3019 ◽

2015 ◽

Vol 31 (3) ◽

pp. 746-753 ◽

Cited By ~ 22

Author(s):

Qianfen Zhuang ◽

Yong Wang ◽

Yongnian Ni

Keyword(s):

Quantum Dots ◽

Citric Acid ◽

Microwave Irradiation ◽

Live Cell Imaging ◽

Cell Imaging ◽

Solid Phase Synthesis ◽

Solid Phase ◽

Graphene Quantum Dots ◽

Food Additive ◽

Phase Synthesis

Download Full-text

One-pot synthesis of N-doped graphene quantum dots as highly sensitive fluorescent sensor for detection of mercury ions water solutions

Materials Research Express ◽

10.1088/2053-1591/ab3006 ◽

2019 ◽

Vol 6 (9) ◽

pp. 095615 ◽

Cited By ~ 3

Author(s):

Yue Yang ◽

Xuechun Xiao ◽

Xinxin Xing ◽

Zhezhe Wang ◽

Tong Zou ◽

...

Keyword(s):

Quantum Dots ◽

Fluorescent Sensor ◽

Graphene Quantum Dots ◽

Mercury Ions ◽

One Pot ◽

Water Solutions ◽

One Pot Synthesis ◽

Highly Sensitive ◽

Doped Graphene

Download Full-text

One-pot microwave-assisted green synthesis of amine-functionalized graphene quantum dots for high visible light photocatalytic application

Comptes Rendus Chimie ◽

10.1016/j.crci.2019.10.005 ◽

2019 ◽

Vol 22 (11-12) ◽

pp. 822-828 ◽

Cited By ~ 1

Author(s):

Tran Van Tam ◽

T.M. Altahtamouni ◽

Vien Le Minh ◽

Huynh Ky Phuong Ha ◽

Nguyen Thi Kim Chung ◽

...

Keyword(s):

Quantum Dots ◽

Visible Light ◽

Green Synthesis ◽

Graphene Quantum Dots ◽

Functionalized Graphene ◽

One Pot ◽

Microwave Assisted ◽

Amine Functionalized ◽

Photocatalytic Application ◽

Visible Light Photocatalytic

Download Full-text

Recent Advances in the Cancer Bioimaging with Graphene Quantum Dots

Current Medicinal Chemistry ◽

10.2174/0929867324666170223154145 ◽

2018 ◽

Vol 25 (25) ◽

pp. 2876-2893 ◽

Cited By ~ 15

Author(s):

Keheng Li ◽

Xinna Zhao ◽

Gang Wei ◽

Zhiqiang Su

Keyword(s):

Quantum Dots ◽

Biomedical Applications ◽

Cell Imaging ◽

Graphene Quantum Dots ◽

Biological Properties ◽

Live Cells ◽

Physical Chemical ◽

Specific Cancer ◽

Good Biocompatibility ◽

Low Cytotoxicity

Fluorescent graphene quantum dots (GQDs) have attracted increasing interest in cancer bioimaging due to their stable photoluminescence (PL), high stability, low cytotoxicity, and good biocompatibility. In this review, we present the synthesis and chemical modification of GQDs firstly, and then introduce their unique physical, chemical, and biological properties like the absorption, PL, and cytotoxicity of GQDs. Finally and most importantly, the recent applications of GQDs in cancer bioimaging are demonstrated in detail, in which we focus on the biofunctionalization of GQDs for specific cancer cell imaging and real-time molecular imaging in live cells. We expect this work would provide valuable guides on the synthesis and modification of GQDs with adjustable properties for various biomedical applications in the future.

Download Full-text