A new partition testing strategy for multiple endpoints

2012 ◽  
Vol 31 (20) ◽  
pp. 2151-2168
Author(s):  
Bushi Wang ◽  
Xinping Cui
Keyword(s):  
Testing Strategy ◽  
Multiple Endpoints ◽  
Partition Testing

scholarly journals Partition testing in dose–response studies with multiple endpoints

2007 ◽  
Vol 6 (3) ◽  
pp. 181-192 ◽  
Author(s):  
Yi Liu ◽  
Jason Hsu ◽  
Stephen Ruberg
Keyword(s):  
Dose Response ◽  
Multiple Endpoints ◽  
Partition Testing

Pipeline Product Quality Testing Based on Adaptive SIFT Matching Technology

2011 ◽  
Vol 71-78 ◽  
pp. 4151-4154
Author(s):  
Ju Bao Qu ◽  
Shu Juan Wang
Keyword(s):  
Product Quality ◽  
Adaptive Algorithm ◽  
Assembly Line ◽  
Point Of View ◽  
Experimental Results ◽  
Testing Strategy ◽  
Harris Corner ◽  
Quality Testing ◽  
Partition Testing

The problem of product quality testing on the assembly line is proposed SIFT-based adaptive algorithm and Harris corner supplementation, achieved through the SIFT matching the product point of view, position, brightness, distance calibration, the product matches the partition testing strategy to ensure that the product accessories The number and quality of the normative. Experimental results show that the detected speed and robustness.

Mascot 3: a testing strategy

1986 ◽  
Vol 1 (3) ◽  
pp. 136 ◽  
Author(s):  
A.R. Riddiough
Keyword(s):  
Testing Strategy

Optimal Testing Strategy for Containing COVID-19: A Case-Study on Indian Migrant Worker Population

2020 ◽  
Author(s):  
Manxi Wu ◽  
Devendra Shelar ◽  
Raja Gopalakrishnan ◽  
Saurabh Amin
Keyword(s):  
Migrant Worker ◽  
Testing Strategy

Mean reversion in corporate leverage: evidence from India

2019 ◽  
Vol 45 (9) ◽  
pp. 1183-1198
Author(s):  
Gaurav S. Chauhan ◽  
Pradip Banerjee
Keyword(s):  
Capital Structure ◽  
Emerging Market ◽  
Simulated Data ◽  
Mean Reversion ◽  
Developed Countries ◽  
Data Sets ◽  
Debt Ratio ◽  
Testing Strategy ◽  
Content Type ◽  
Financing Behavior

Purpose Recent papers on target capital structure show that debt ratio seems to vary widely in space and time, implying that the functional specifications of target debt ratios are of little empirical use. Further, target behavior cannot be adjudged correctly using debt ratios, as they could revert due to mechanical reasons. The purpose of this paper is to develop an alternative testing strategy to test the target capital structure. Design/methodology/approach The authors make use of a major “shock” to the debt ratios as an event and think of a subsequent reversion as a movement toward a mean or target debt ratio. By doing this, the authors no longer need to identify target debt ratios as a function of firm-specific variables or any other rigid functional form. Findings Similar to the broad empirical evidence in developed economies, there is no perceptible and systematic mean reversion by Indian firms. However, unlike developed countries, proportionate usage of debt to finance firms’ marginal financing deficits is extensive; equity is used rather sparingly. Research limitations/implications The trade-off theory could be convincingly refuted at least for the emerging market of India. The paper here stimulated further research on finding reasons for specific financing behavior of emerging market firms. Practical implications The results show that the firms’ financing choices are not only depending on their own firm’s specific variables but also on the financial markets in which they operate. Originality/value This study attempts to assess mean reversion in debt ratios in a unique but reassuring manner. The results are confirmed by extensive calibration of the testing strategy using simulated data sets.

scholarly journals Neutralization of SARS-CoV-2 with IgG from COVID-19-convalescent plasma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kenji Maeda ◽  
Nobuyo Higashi-Kuwata ◽  
Noriko Kinoshita ◽  
Satoshi Kutsuna ◽  
Kiyoto Tsuchiya ◽  
...  
Keyword(s):  
Immune Response ◽  
Clinical Utility ◽  
Plasma Sample ◽  
Temporal Changes ◽  
Rapid Decline ◽  
Multiple Endpoints ◽  
Neutralization Activity ◽  
Neutralizing Activity ◽  
Binding Antibody ◽  
Potent Immune Response

AbstractWhile there are various attempts to administer COVID-19-convalescent plasmas to SARS-CoV-2-infected patients, neither appropriate approach nor clinical utility has been established. We examined the presence and temporal changes of the neutralizing activity of IgG fractions from 43 COVID-19-convalescent plasmas using cell-based assays with multiple endpoints. IgG fractions from 27 cases (62.8%) had significant neutralizing activity and moderately to potently inhibited SARS-CoV-2 infection in cell-based assays; however, no detectable neutralizing activity was found in 16 cases (37.2%). Approximately half of the patients (~ 41%), who had significant neutralizing activity, lost the neutralization activity within ~ 1 month. Despite the rapid decline of neutralizing activity in plasmas, good amounts of SARS-CoV-2-S1-binding antibodies were persistently seen. The longer exposure of COVID-19 patients to greater amounts of SARS-CoV-2 elicits potent immune response to SARS-CoV-2, producing greater neutralization activity and SARS-CoV-2-S1-binding antibody amounts. The dilution of highly-neutralizing plasmas with poorly-neutralizing plasmas relatively readily reduced neutralizing activity. The presence of good amounts of SARS-CoV-2-S1-binding antibodies does not serve as a surrogate ensuring the presence of good neutralizing activity. In selecting good COVID-19-convalescent plasmas, quantification of neutralizing activity in each plasma sample before collection and use is required.

scholarly journals Pooled testing with replication as a mass testing strategy for the COVID-19 pandemics

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Julius Žilinskas ◽  
Algirdas Lančinskas ◽  
Mario R. Guarracino
Keyword(s):  
Real Time ◽  
Real Time Pcr ◽  
Group Testing ◽  
Testing Strategy ◽  
Testing Technique ◽  
Testing Procedures ◽  
Pooled Testing ◽  
Replication Scheme ◽  
Speed Up ◽  
Multiple Patients

AbstractDuring the COVID-19 pandemic it is essential to test as many people as possible, in order to detect early outbreaks of the infection. Present testing solutions are based on the extraction of RNA from patients using oropharyngeal and nasopharyngeal swabs, and then testing with real-time PCR for the presence of specific RNA filaments identifying the virus. This approach is limited by the availability of reactants, trained technicians and laboratories. One of the ways to speed up the testing procedures is a group testing, where the swabs of multiple patients are grouped together and tested. In this paper we propose to use the group testing technique in conjunction with an advanced replication scheme in which each patient is allocated in two or more groups to reduce the total numbers of tests and to allow testing of even larger numbers of people. Under mild assumptions, a 13 ×  average reduction of tests can be achieved compared to individual testing without delay in time.

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