Corynebacterium parvum Outlook and Future

1975 ◽  
pp. 413-418
Author(s):  
Stephen K. Carter
1989 ◽  
Vol 10 (3) ◽  
pp. 501-507 ◽  
Author(s):  
A. Pitigala-Arachchi ◽  
J.B. Matthews ◽  
C. Scully ◽  
S.S. Prime

Parasitology ◽  
1984 ◽  
Vol 89 (3) ◽  
pp. 417-424 ◽  
Author(s):  
F. E. G. Cox ◽  
Stephanie M. Millott

SUMMARYMice pre-treated withCorynebacterium parvumand later challenged withPlasmodium vinckeibecome infected but do not die whereas control mice do. When pre-treated mice were challenged with 1, 10, 1 × 102, 1 × 104, 1 × 105or 1 × 106parasites, the pre-patent periods correlated directly with the number of parasites injected, but the subsequent parasitaemias reached similar levels. This suggests that parasite killing, resulting from pre-treatment withC. parvum, is not triggered until the parasite load has reached a particular threshold. The injection of alloxan monohydrate, which brings about the release of toxic oxygen inter mediates thought to be involved in non-specific immunity, has little effect onP. vinckeiinfections until the parasitaemia is relatively high. This indicates that oxygen-mediated parasite killing also does not occur until the parasitaemia has reached a particular threshold. It is suggested that it is only at relatively high parasitaemias that the factors involved in parasite killing are able to enter the infected red blood cells.


1967 ◽  
Vol 5 (6) ◽  
pp. 1510-1524 ◽  
Author(s):  
J. G. HOWARD ◽  
G. BIOZZI ◽  
C. STIFFEL ◽  
D. MOUTON ◽  
P. LIACOPOULOS

1979 ◽  
Vol 51 (4) ◽  
pp. 278-282 ◽  
Author(s):  
ELIZABETH C. PURVES ◽  
M. SNELL ◽  
W. A. COPE ◽  
I. E. ADDISON ◽  
R.F.P. COPLAND ◽  
...  

The Lancet ◽  
1975 ◽  
Vol 306 (7944) ◽  
pp. 1090-1091 ◽  
Author(s):  
R OSSORIO

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