Nigella sativa Seed Extract in Green Synthesis and Nanocomposite

2020 ◽  
pp. 179-190
Author(s):  
Raya Soltane ◽  
Dalila Mtat ◽  
Amani Chrouda ◽  
Noof Alzahrani ◽  
Youssef O. Al-Ghamdi ◽  
...  
Keyword(s):  
Green Synthesis ◽  
Nigella Sativa ◽  
Seed Extract ◽  
Nigella Sativa Seed

Green synthesis, characterization and photocatalytic activity of silver nanoparticles synthesized with Nigella Sativa seed extract

2021 ◽  
Vol 763 ◽  
pp. 138218
Author(s):  
Kishore Chand ◽  
Cheng Jiao ◽  
Muhammad Nazim Lakhan ◽  
Ahmer Hussain Shah ◽  
Vinod Kumar ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Photocatalytic Activity ◽  
Green Synthesis ◽  
Nigella Sativa ◽  
Seed Extract ◽  
Nigella Sativa Seed

scholarly journals Comparison of Antibacterial Efficacy of Fenugreek Seed Extract Rinse and Nigella Sativa Seed Extract Rinse against Streptococcus Mutant Colonies

2021 ◽  
pp. 79-86
Author(s):  
Nasima Iqbal ◽  
ATA UR Rehman ◽  
Syeda Amber Zaidi ◽  
Kiran Khan ◽  
Lubna Farooq ◽  
...  
Keyword(s):  
Nigella Sativa ◽  
Positive Control ◽  
Seed Extract ◽  
Control Group ◽  
Distilled Water ◽  
Post Hoc Analysis ◽  
Fenugreek Seed ◽  
Study Participants ◽  
Post Hoc ◽  
Nigella Sativa Seed

Background: Dental infections were caused by the bacterium overgrowth on the surface of the tooth, and treatment should always be set up to prevent this development.Antibiotics have long been used as a conventional antibacterial medication, but their overuse has resulted in microbes gaining resistance to many of the antibiotics, trying to make many commercialized therapeutic remedies ineffectual and resulting to infection recurrence. In this regard we aim to analyze the antibacterial activity of nigella sativa seeds’ and fenugreek seed extract rinses against S. mutans' colonies. Methodology: It was a preclinical experimental study conducted at Baqai Medical and Dental College Karachi., from January - June 2021. Calculated sample size was n = 80 Consecutive sampling technique was used. Plaque of study participants was collected on sterile strips that was transported to laboratory for culture in sterile containers.The extract of Fenugreek seed and nigella sativa seed was kept in an airtight bottle and stored in a refrigerator till usage. The extracts were diluted in distilled water in 1:4 (Extract: Distilled water). Study participants were instructed to not brush their teeth before sampling. Study participants were divided into four groups (negative control, positive control, fenugreek seed extract group and Nigella sativa group) each group had 20 participants. Diluted Fenugreek seed extract and Nigella sativa extract was given to experimental groups for rinses. Results: There was significant decrease in number of colonies in positive controls, fenugreek seed extract group and nigella sativa extract group and there was no change in number of colonies in control group. Furthermore, the analysis showed significant (p-value = 0.001) difference among the groups followed by post hoc analysis. Post hoc analysis showed no difference between positive control, fenugreek seed extract group and nigella sativa group. Conclusion: Fenugreek seed extract and Nigella Sativa seed extract showed comparable antibacterial properties. Also, the effect was found to be similar to commercially available mouth rinse.

The possible prophylactic effect of Nigella sativa seed extract in asthmatic patients

2007 ◽  
Vol 21 (5) ◽  
pp. 559-566 ◽  
Author(s):  
Mohammad Hossein Boskabady ◽  
H. Javan ◽  
M. Sajady ◽  
H. Rakhshandeh
Keyword(s):  
Nigella Sativa ◽  
Seed Extract ◽  
Prophylactic Effect ◽  
Asthmatic Patients ◽  
Nigella Sativa Seed

scholarly journals Nigella sativa seed extract protects against cadmium-induced cardiotoxicity in rats

2020 ◽  
Vol 10 (1-s) ◽  
pp. 174-177
Author(s):  
Ikenna Kingsley Uchendu ◽  
Ebuka Bitrus Nnedu ◽  
Ifeoma Blessing Ekeigwe
Keyword(s):  
Histopathological Examination ◽  
Nigella Sativa ◽  
Intraperitoneal Administration ◽  
Negative Control ◽  
Seed Extract ◽  
Albino Rats ◽  
High Dose ◽  
Protective Effects ◽  
Oral Group ◽  
Nigella Sativa Seed

Objective:  The aim of this study is to investigate the protective effects of methanolic extract of Nigella sativa (MENS) (Black seed) against cardiotoxicity of cadmium in albino rats.  Methods: Twenty five (25) male albino rats, weighing (150-170g), were randomly grouped into five groups: A-E. Group B (Negative Control) received intraperitoneal administration of cadmium chloride (CdCl2, 5mg/kg) only, group C received CdCl2 and low dose MENS (300mg/kg, oral), group D received CdCl2 and high dose MENS (600mg/kg, oral), group E (Positive control) received CdCl2 and Vitamin C (200mg/kg, oral), for 7 days. No treatment was administered to group A (Normal control). Cardiac injury was assessed by measuring serum levels of Aspartate aminotransferase (AST), Lactate dehydrogenase (LDH) and Creatine kinase (CK-MB) using standard methods. The heart was harvested for histopathological examination. Results: CdCl2 induced significant cardiotoxicity with marked elevation in the levels of biochemical markers of cardiac functions (p<0.05 or p<0.01); these were however attenuated by MENS. Histopathological examination of the heart sections supported the biochemical findings. Conclusion: Nigella sativa seed extract is potentially cardioprotective against harmful chemical toxins such as cadmium. Keywords: Cadmium, CdCl2, Nigella sativa, Medicinal food, cardiotoxicity

scholarly journals Nigella Sativa Seed Extract Ointment Increasing the Amount of Healing Fibroblast and Collagen on Balb/C Mice

Sains Medika ◽  
2017 ◽  
Vol 8 (1) ◽  
pp. 15
Author(s):  
Sri Mastuti ◽  
Djoko Tri Hadi ◽  
Chodidjah Chodidjah
Keyword(s):  
Nigella Sativa ◽  
Seed Extract ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Nigella Sativa Seed

LATAR BELAKANG: Luka tidak sembuh dalam waktu lama dengan berbagai penyebab merupakan masalah yang sering ditemukan dalam berbagai disiplin kedokteran. Kejadian ini salah satu sumber utama morbiditas, penyebab gangguan psikologis para penderita, meningkatkan biaya pengobatan dan kehilangan jam kerja pada penderita usia produktif.�TUJUAN: untuk mengetahui pengaruh ekstrak biji jinten hitam (Nigella sativa) dalam sediaan salep sebanyak 40% dan 60% terhadap jumlah fibroblas dan kolagen pada penyembuhan luka sayat mencit balb/c.METODE: Penelitian eksperimental dengan rancangan �post test only control group design� pada 48 ekor mencit jantan galur balb/c, dibagi menjadi 4 kelompok pengujian fibroblast (24 ekor) dan 4 kelompok pengujian kolagen (24 ekor). Masing-masing kelompok terdiri dari 6 ekor sampel yang dipilih secara random. Salep ekstrak Nigella sativa dengan konsentrasi 40% dan dengan konsentrasi 60% dioles sebanyak 3x sehari selama 7 hari pada kelompok fibroblast dan selama 14 hari pada kelompok kolagen. Data dianalisis dengan Kruskal-Wallis.HASIL: Analisis jumlah fibroblast antara kelompok kontrol/tidak diberikan perlakuan dan kelompok yang diberikan salep garamycin terdapat perbedaan (p value =0,010), antara kelompok kontrol dan kelompok yang diberikan salep ekstrak jinten hitam 40 % tidak ada perbedaan (p value =0,065), pada kelompok yang diberikan salep ekstrak jinten hitam 60 % terdapat perbedaan (p value =0,025). Hasil analisis jumlah kolagen menunjukkan perbedaan antara semua kelompok (p value =0,004).KESIMPULAN: Pemberian salep ekstrak biji jinten hitam (Nigella sativa) dapat meningkatkan jumlah fibroblas dan kolagen pada penyembuhan� luka sayat kulit mencit galur balb/c.

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