Identification of an Arabidopsis Locus that Governs Avirulence Gene-Specific Disease Resistance

1993 ◽  
pp. 417-421
Author(s):  
B. N. Kunkel ◽  
A. F. Bent ◽  
D. Dahlbeck ◽  
R. W. Innes ◽  
B. J. Staskawicz
Keyword(s):  
Disease Resistance ◽  
Avirulence Gene ◽  
Specific Disease

scholarly journals Identification of Three Putative Signal Transduction Genes Involved in R Gene-Specified Disease Resistance in Arabidopsis

Genetics ◽  
1999 ◽  
Vol 152 (1) ◽  
pp. 401-412 ◽  
Author(s):  
Randall F Warren ◽  
Peter M Merritt ◽  
Eric Holub ◽  
Roger W Innes
Keyword(s):  
Disease Resistance ◽  
Pseudomonas Syringae ◽  
Resistance Genes ◽  
Virulent Strain ◽  
Disease Resistance Genes ◽  
Avirulence Gene ◽  
Detectable Effect ◽  
Disease Resistance Gene ◽  
Protein Functions ◽  
Signal Transduction Genes

Abstract The RPS5 disease resistance gene of Arabidopsis mediates recognition of Pseudomonas syringae strains that possess the avirulence gene avrPphB. By screening for loss of RPS5-specified resistance, we identified five pbs (avrPphB susceptible) mutants that represent three different genes. Mutations in PBS1 completely blocked RPS5-mediated resistance, but had little to no effect on resistance specified by other disease resistance genes, suggesting that PBS1 facilitates recognition of the avrPphB protein. The pbs2 mutation dramatically reduced resistance mediated by the RPS5 and RPM1 resistance genes, but had no detectable effect on resistance mediated by RPS4 and had an intermediate effect on RPS2-mediated resistance. The pbs2 mutation also had varying effects on resistance mediated by seven different RPP (recognition of Peronospora parasitica) genes. These data indicate that the PBS2 protein functions in a pathway that is important only to a subset of disease-resistance genes. The pbs3 mutation partially suppressed all four P. syringae-resistance genes (RPS5, RPM1, RPS2, and RPS4), and it had weak-to-intermediate effects on the RPP genes. In addition, the pbs3 mutant allowed higher bacterial growth in response to a virulent strain of P. syringae, indicating that the PBS3 gene product functions in a pathway involved in restricting the spread of both virulent and avirulent pathogens. The pbs mutations are recessive and have been mapped to chromosomes I (pbs2) and V (pbs1 and pbs3).

RPS2, an Arabidopsis Disease Resistance Locus Specifying Recognition of Pseudomonas syringae Strains Expressing the Avirulence Gene avrRpt2

1993 ◽  
Vol 5 (8) ◽  
pp. 865 ◽  
Author(s):  
Barbara N. Kunkel ◽  
Andrew F. Bent ◽  
Douglas Dahlbeck ◽  
Roger W. Innes ◽  
Brian J. Staskawicz
Keyword(s):  
Disease Resistance ◽  
Pseudomonas Syringae ◽  
Avirulence Gene ◽  
Resistance Locus

scholarly journals Identification and characterization of the Non-race specific Disease Resistance 1 (NDR1) orthologous protein in coffee

2011 ◽  
Vol 11 (1) ◽  
pp. 144 ◽  
Author(s):  
Jean-Luc Cacas ◽  
Anne-Sophie Petitot ◽  
Louis Bernier ◽  
Joan Estevan ◽  
Geneviève Conejero ◽  
...  
Keyword(s):  
Disease Resistance ◽  
Orthologous Protein ◽  
Specific Disease ◽  
Identification And Characterization

scholarly journals Novel Cucumis Enzymes Associated with Host-Specific Disease Resistance to Phytophthora melonis

2020 ◽  
Author(s):  
Mehdi Esfahani ◽  
Lida Hashemi Hashemi ◽  
Abbas Nasehi ◽  
Ava Nasr esfahani ◽  
Arman Nasr Esfahani
Keyword(s):  
Disease Resistance ◽  
Specific Disease ◽  
Phytophthora Melonis

scholarly journals Mutational Analysis of the Arabidopsis RPS2 Disease Resistance Gene and the Corresponding Pseudomonas syringae avrRpt2 Avirulence Gene

2001 ◽  
Vol 14 (2) ◽  
pp. 181-188 ◽  
Author(s):  
Michael J. Axtell ◽  
Timothy W. McNellis ◽  
Mary Beth Mudgett ◽  
Caroline S. Hsu ◽  
Brian J. Staskawicz
Keyword(s):  
Disease Resistance ◽  
Resistance Gene ◽  
Pseudomonas Syringae ◽  
Resistance Genes ◽  
Mutational Analysis ◽  
Defense Responses ◽  
Avirulence Gene ◽  
Disease Resistance Gene ◽  
In Planta ◽  
Hypersensitive Cell Death

Plants have evolved a large number of disease resistance genes that encode proteins containing conserved structural motifs that function to recognize pathogen signals and to initiate defense responses. The Arabidopsis RPS2 gene encodes a protein representative of the nucleotide-binding site-leucine-rich repeat (NBS-LRR) class of plant resistance proteins. RPS2 specifically recognizes Pseudomonas syringae pv. tomato strains expressing the avrRpt2 gene and initiates defense responses to bacteria carrying avrRpt2, including a hypersensitive cell death response (HR). We present an in planta mutagenesis experiment that resulted in the isolation of a series of rps2 and avrRpt2 alleles that disrupt the RPS2-avrRpt2 gene-for-gene interaction. Seven novel avrRpt2 alleles incapable of eliciting an RPS2-dependent HR all encode proteins with lesions in the C-terminal portion of AvrRpt2 previously shown to be sufficient for RPS2 recognition. Ten novel rps2 alleles were characterized with mutations in the NBS and the LRR. Several of these alleles code for point mutations in motifs that are conserved among NBS-LRR resistance genes, including the third LRR, which suggests the importance of these motifs for resistance gene function.

scholarly journals RPS2, an Arabidopsis disease resistance locus specifying recognition of Pseudomonas syringae strains expressing the avirulence gene avrRpt2.

1993 ◽  
Vol 5 (8) ◽  
pp. 865-875 ◽  
Author(s):  
B N Kunkel ◽  
A F Bent ◽  
D Dahlbeck ◽  
R W Innes ◽  
B J Staskawicz
Keyword(s):  
Disease Resistance ◽  
Pseudomonas Syringae ◽  
Avirulence Gene ◽  
Resistance Locus
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