Cancer-Preventive and Antitumour Effects of Sandalwood Oil and Alpha-Santalol

Study of the anti-inflammatory and antitumour effects of a hydroethanolic extract of the plant Piper marginatum

Planta Medica ◽

10.1055/s-0029-1234625 ◽

2009 ◽

Vol 75 (09) ◽

Author(s):

A Contreras ◽

J Villasmil ◽

MJ Abad ◽

M Arsenak ◽

F Michelangeli ◽

...

Keyword(s):

Anti Inflammatory ◽

Hydroethanolic Extract ◽

Antitumour Effects

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A Comparison of the Composition of Selected Commercial Sandalwood Oils with the International Standard

Molecules ◽

10.3390/molecules26082249 ◽

2021 ◽

Vol 26 (8) ◽

pp. 2249

Author(s):

Malgorzata Kucharska ◽

Barbara Frydrych ◽

Wiktor Wesolowski ◽

Jadwiga A. Szymanska ◽

Anna Kilanowicz

Keyword(s):

Mass Spectrometry Analysis ◽

Santalum Album ◽

Benzyl Benzoate ◽

Spectrometry Analysis ◽

Correct Information ◽

Three Samples ◽

Two Samples ◽

High Street ◽

Chromatographic Profile ◽

Sandalwood Oil

Sandalwood oils are highly desired but expensive, and hence many counterfeit oils are sold in high street shops. The study aimed to determine the content of oils sold under the name sandalwood oil and then compare their chromatographic profile and α- and β santalol content with the requirements of ISO 3518:2002. Gas chromatography with mass spectrometry analysis found that none of the six tested “sandalwood” oils met the ISO standard, especially in terms of α-santalol content. Only one sample was found to contain both α- and β-santalol, characteristic of Santalum album. In three samples, valerianol, elemol, eudesmol isomers, and caryophyllene dominated, indicating the presence of Amyris balsamifera oil. Another two oil samples were found to be synthetic mixtures: benzyl benzoate predominating in one, and synthetic alcohols, such as javanol, polysantol and ebanol, in the other. The product label only gave correct information in three cases: one sample containing Santalum album oil and two samples containing Amyris balsamifera oil. The synthetic samples described as 100% natural essential oil from sandalwood are particularly dangerous and misleading to the consumer. Moreover, the toxicological properties of javanol, polysantol and ebanol, for example, are unknown.

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Targeted dual inhibition of c‐Met/VEGFR2 signalling by foretinib improves antitumour effects of nanoparticle paclitaxel in gastric cancer models

Journal of Cellular and Molecular Medicine ◽

10.1111/jcmm.16362 ◽

2021 ◽

Author(s):

Meghan Grojean ◽

Margaret A. Schwarz ◽

Johann R. Schwarz ◽

Sazzad Hassan ◽

Urs von Holzen ◽

...

Keyword(s):

Gastric Cancer ◽

Cancer Models ◽

Dual Inhibition ◽

Antitumour Effects

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Conformational calculations on odoriferous molecules of sandalwood, I. The search for the odoriferous principle of sandalwood oil

Monatshefte für Chemie - Chemical Monthly ◽

10.1007/bf00809685 ◽

1988 ◽

Vol 119 (6-7) ◽

pp. 711-715 ◽

Cited By ~ 12

Author(s):

Anton Beyer ◽

Peter Wolschann ◽

Armin Becker ◽

Elisabeth Pranka ◽

Gerhard Buchbauer

Keyword(s):

Sandalwood Oil ◽

Conformational Calculations

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Antifungal features and properties of chitosan/sandalwood oil Pickering emulsion coating stabilized by appropriate cellulose nanofiber dosage for fresh fruit application

Scientific Reports ◽

10.1038/s41598-021-98074-w ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Ata Aditya Wardana ◽

Arisa Koga ◽

Fumina Tanaka ◽

Fumihiko Tanaka

Keyword(s):

Laser Scanning ◽

Cellulose Nanofibers ◽

Membrane Integrity ◽

Pickering Emulsion ◽

Fresh Fruit ◽

Laser Scanning Microscopy ◽

Confocal Laser ◽

Coating Film ◽

Sandalwood Oil ◽

Unstable Emulsion

AbstractA novel composite edible coating film was developed from 0.8% chitosan (CS) and 0.5% sandalwood oil (SEO). Cellulose nanofibers (CNFs) were used as a stabilizer agent of oil-in-water Pickering emulsion. We found four typical groups of CNF level-dependent emulsion stabilization, including (1) unstable emulsion in the absence of CNFs; (2) unstable emulsion (0.006–0.21% CNFs); (3) stable emulsion (0.24–0.31% CNFs); and (4) regular emulsion with the addition of surfactant. Confocal laser scanning microscopy was performed to reveal the characteristics of droplet diameter and morphology. Antifungal tests against Botrytis cinerea and Penicillium digitatum, between emulsion coating stabilized with CNFs (CS-SEOpick) and CS or CS-SEO was tested. The effective concentration of CNFs (0.24%) may improve the performance of CS coating and maintain CS-SEO antifungal activity synergistically confirmed with a series of assays (in vitro, in vivo, and membrane integrity changes). The incorporation of CNFs contributed to improve the functional properties of CS and SEO-loaded CS including light transmission at UV and visible light wavelengths and tensile strength. Atomic force microscopy and scanning electron microscopy were employed to characterize the biocompatibility of each coating film formulation. Emulsion-CNF stabilized coating may have potential applications for active coating for fresh fruit commodities.

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