Effect of malathion on nucleic acid synthesis in phytohemagglutinin-stimulated human lymphocytes

1980 ◽  
Vol 56 (2) ◽  
pp. 189-194 ◽  
Author(s):  
A. Czajkowska ◽  
Z. Walter
Keyword(s):  
Nucleic Acid ◽  
Human Lymphocytes ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis

RELATIONSHIP BETWEEN NUCLEIC ACIDS, HISTONE AND NON-HISTONE PROTEIN SYNTHESIS IN HUMAN LYMPHOCYTES STIMULATED WITH PHYTOHEMAGGLUTININ

1970 ◽  
Vol 12 (1) ◽  
pp. 151-159 ◽  
Author(s):  
Anil B. Mukherjee
Keyword(s):  
Protein Synthesis ◽  
Nucleic Acid ◽  
Nucleic Acids ◽  
Temporal Relationship ◽  
Human Lymphocytes ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis ◽  
Culture Period ◽  
Histone Protein ◽  
Pha Stimulation

The temporal relationship between the synthesis of histone and non-histone proteins and nucleic acids has been investigated by autoradiography in PHA stimulated human lymphocytes throughout the 72-hour culture period. It was found that a significant amount of 3H-arginine and 3H-lysine incorporation took place at a time when the cells were actively synthesizing DNA. Non-histone protein synthesis, as evidenced by 3H-tryptophan incorporation, was found to be dependent on PHA stimulation in human lymphocytes. Inhibition of histone and/or non-histone protein synthesis leads to the inhibition of nucleic acid synthesis.

scholarly journals Role of Folic Acid and Energy Intake in Nucleic Acid Synthesis

1959 ◽  
Vol 234 (3) ◽  
pp. 625-627
Author(s):  
Ranjan Mehta ◽  
David A. Vaughan ◽  
Shreepad R. Wagle ◽  
Kendall D. Barbee ◽  
S.P. Mistry ◽  
...  
Keyword(s):  
Folic Acid ◽  
Nucleic Acid ◽  
Energy Intake ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis
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