Galactose metabolism in transferase-deficient galactosaemic and normal long-term lymphoid cell lines

1987 ◽  
Vol 10 (4) ◽  
pp. 347-358 ◽  
Author(s):  
N. G. Beratis ◽  
L. Wilbur
1973 ◽  
Vol 137 (3) ◽  
pp. 838-843 ◽  
Author(s):  
T. H. Hütteroth ◽  
H. Cleve ◽  
S. D. Litwin ◽  
M. D. Poulik

ß2-microglobulin was detected on the cell surface and in the medium of human lymphoid cells established in long-term culture. The secretion of ß2-microglobulin was relatively uniform when different cell lines were compared, whereas IgG production varied widely. κ- and µ-membrane antigens were modulated by specific antibody; ß2-microglobulin was not modulated. Anti-κ and anti-µ antisera had no effect on the expression of membrane ß2-microglobulin, nor had anti-ß2-microglobulin antiserum any effect on the expression of κ- and µ-membrane antigens.


Blood ◽  
1970 ◽  
Vol 35 (4) ◽  
pp. 539-542 ◽  
Author(s):  
SUSAN W. BRODER ◽  
P. R. GLADE ◽  
K. HIRSCHHORN

Abstract A highly purified, non-hemagglutinating PHA used in minimal blastogenic doses was non-toxic to established human lymphoid cell lines. PHA given at the beginning of primary culture or repeatedly throughout the initial six weeks of culture did not interfere with the establishment of peripheral lymphocytes in long-term suspension culture. Permanent cell lines have been obtained following weekly administration of PHA in blastogenic and subthreshold doses. Nonhemagglutinating PHA appeared to be non-toxic to these peripheral lymphocyte cultures and may increase their potential for long-term proliferation.


The Lancet ◽  
1972 ◽  
Vol 300 (7775) ◽  
pp. 482 ◽  
Author(s):  
LynnD. Fleisher ◽  
NicholasG. Beratis ◽  
Kurt Hirschhorn ◽  
GeraldE. Gaull

1981 ◽  
Vol 106 (3) ◽  
pp. 369-374
Author(s):  
L. Guarini ◽  
J. A. Sturman ◽  
G. E. Gaull ◽  
N. G. Beratis

1976 ◽  
Vol 276 (1 International) ◽  
pp. 584-591 ◽  
Author(s):  
B. W. Papermaster ◽  
O. A. Holtermann ◽  
M. C. McDaniel ◽  
E. Klein ◽  
I. Djerassi ◽  
...  

Toxicology ◽  
2005 ◽  
Vol 210 (1) ◽  
pp. 81-91 ◽  
Author(s):  
Fiorenza Minervini ◽  
Francesca Fornelli ◽  
Giacomo Lucivero ◽  
Ciro Romano ◽  
Angelo Visconti

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