Phagocytosis of14C clnitrophenyl poly L-lysine by peritoneal exudate cells from guinea-pigs

1970 ◽  
Vol 26 (5) ◽  
pp. 534-535
Author(s):  
B. K. Davis
Keyword(s):  
Guinea Pigs ◽  
Peritoneal Exudate ◽  
Peritoneal Exudate Cells

scholarly journals POLYSACCHARIDE IN DELAYED HYPERSENSITIVITY

1970 ◽  
Vol 131 (1) ◽  
pp. 189-206 ◽  
Author(s):  
Robert J. Gerety ◽  
Rodolfo W. Ferraresi ◽  
Sidney Raffel
Keyword(s):  
Guinea Pigs ◽  
Early Phase ◽  
Peritoneal Exudate ◽  
Delayed Hypersensitivity ◽  
Skin Tests ◽  
Type Ii ◽  
Antibody Synthesis ◽  
Peritoneal Exudate Cells ◽  
Freund's Adjuvant ◽  
Inhibition Reaction

A highly purified pneumococcal polysaccharide (Type II SSS) is a very efficient inducer of delayed hypersensitivity in random-bred guinea pigs. The cellular reactivity induced by this polysaccharide administered subcutaneously in complete Freund's adjuvant is of "tuberculin type"; it increases in intensity with time after the sensitizing injection, as judged by skin tests, the macrophage inhibition reaction and transfer of reactivity by peritoneal exudate cells. By contrast, the cellular reactivity induced by this immunogen in the absence of mycobacterial adjuvant has the characteristics of "Jones-Mote" reactivity. It is best seen at about 1 wk after sensitization; the reactions are characteristically little indurated and show histologic differences from tuberculin type responses; and the reactive state begins to disappear by 2–3 wk, with the accession of Arthus reactivity. This type of delayed reactivity may be related to an early phase of antibody synthesis.

scholarly journals STUDIES ON THE IMMUNE RESPONSE TO A CHARACTERIZED ANTIGENIC DETERMINANT OF THE TOBACCO MOSAIC VIRUS PROTEIN

1970 ◽  
Vol 131 (1) ◽  
pp. 133-148 ◽  
Author(s):  
Lynn Spitler ◽  
E. Benjamini ◽  
Janis D. Young ◽  
Harvey Kaplan ◽  
H. H. Fudenberg
Keyword(s):  
Immune Response ◽  
Guinea Pigs ◽  
Antigenic Determinant ◽  
Peritoneal Exudate ◽  
Virus Protein ◽  
Spleen Cells ◽  
Present Communication ◽  
Immunological Activity ◽  
Skin Reactions ◽  
Peritoneal Exudate Cells

The following peptides have previously been shown to bind specifically with antibodies to TMVP: (a) An eicosapeptide representing residues 93–112 of TMVP and having the sequence Ileu-Ileu-Glu-Val-Glu-AspNH2-GluNH2-Ala-AspNH2-Pro-Thr-Thr-Ala-Glu-Thr-Leu-Asp-Ala-Thr-Arg. (b) Its C-terminal decapeptide. (c) Its C-terminal pentapeptide. (d) N-octanoyl-C-terminal-tripeptide. (e) (Lys)4-C-terminal-pentapeptide. (f) (Lys)7 C-terminal-pentapeptide. The present communication deals with the investigation of several parameters of the immunological activity of the peptides. The results show that none of the peptides tested were immunogenic in guinea pigs, nor did they stimulate the incorporation of 14C-thymidine by spleen cells derived from TMVP-primed animals. Results also showed that all of the peptides tested could elicit specific delayed and immediate skin reactions in TMVP-sensitized guinea pigs, and furthermore, that the peptides could specifically inhibit the migration of peritoneal exudate cells derived from these animals. The elicitation of delayed skin reactions and the ability to inhibit migration of peritoneal exudate cells were independent of carrier specificity.

scholarly journals Langerhans' cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody.

1986 ◽  
Vol 163 (4) ◽  
pp. 981-997 ◽  
Author(s):  
G Kraal ◽  
M Breel ◽  
M Janse ◽  
G Bruin
Keyword(s):  
Monoclonal Antibody ◽  
Bone Marrow ◽  
Dendritic Cells ◽  
Dendritic Cell ◽  
Langerhans Cells ◽  
Precursor Cells ◽  
Peritoneal Exudate ◽  
Peritoneal Exudate Cells ◽  
Interdigitating Cells

An mAb, NLDC-145, is described that specifically reacts with a group of nonlymphoid dendritic cells including Langerhans cells (LC), veiled cells (VC), and interdigitating cells (IDC). The antibody does not react with precursor cells in bone marrow and blood. Macrophages are not stained by the antibody, but a subpopulation of Ia+ peritoneal exudate cells is recognized. Possible relationships of the various nonlymphoid dendritic cell (NLDC) types are discussed.

scholarly journals Protective Effect of Passively Transferred Immune Peritoneal Exudate Cells in Mice Infected withSalmonella typhimurium

1980 ◽  
Vol 24 (3) ◽  
pp. 255-257 ◽  
Author(s):  
Masayasu Nakano ◽  
Hideko Toyoda ◽  
Tatsuo Saito-Taki ◽  
Masao J. Tanabe
Keyword(s):  
Protective Effect ◽  
Peritoneal Exudate ◽  
Peritoneal Exudate Cells
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