Bone turnover rate predicts the response to estrogen therapy in postmenopausal osteoporosis

1996 ◽  
Vol 6 (S1) ◽  
pp. 223-223
Author(s):  
S. Gonnelli ◽  
D. Agnusdei ◽  
C. Cepollaro ◽  
R. Palmieri ◽  
P. Pondrelli ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Postmenopausal Osteoporosis ◽  
Turnover Rate ◽  
Estrogen Therapy

scholarly journals The Usefulness of Bone Turnover in Predicting the Response to Transdermal Estrogen Therapy in Postmenopausal Osteoporosis

1997 ◽  
Vol 12 (4) ◽  
pp. 624-631 ◽  
Author(s):  
S. Gonnelli ◽  
C. Cepollaro ◽  
C. Pondrelli ◽  
S. Martini ◽  
R. Monaco ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Postmenopausal Osteoporosis ◽  
Estrogen Therapy ◽  
Transdermal Estrogen

Cultures of human osteoblastic cells from dialysis patients: Influence of bone turnover rate on in vitro secretion of interleukin-6 and osteoblastic cell markers

2001 ◽  
Vol 37 (1) ◽  
pp. 30-37 ◽  
Author(s):  
M. Carmen Sánchez ◽  
M. Auxiliadora Bajo ◽  
Rafael Selgas ◽  
Alberto Mate ◽  
M. Jesús Sánchez-Cabezudo ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Interleukin 6 ◽  
Turnover Rate ◽  
Osteoblastic Cells ◽  
Osteoblastic Cell ◽  
Dialysis Patients ◽  
Cell Markers ◽  
Human Osteoblastic Cells

scholarly journals Serumβ-Catenin Levels Associated with the Ratio of RANKL/OPG in Patients with Postmenopausal Osteoporosis

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Xiao-Juan Xu ◽  
Lin Shen ◽  
Yan-Ping Yang ◽  
Rui Zhu ◽  
Bo Shuai ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Postmenopausal Women ◽  
Postmenopausal Osteoporosis ◽  
Bone Turnover Markers ◽  
Enzyme Linked Immunosorbent Assay ◽  
Functional Communication ◽  
Mineral Density ◽  
Wnt Pathways ◽  
Turnover Markers

Objective. To demonstrate the role of Wnt/β-catenin canonical pathway in postmenopausal osteoporosis by evaluating serumβ-catenin levels in patients with postmenopausal osteoporosis and analyzing their possible relationship with serum OPG, RANKL, the ratio of RANKL/OPG, sclerostin, and bone turnover markers.Methods. 480 patients with postmenopausal osteoporosis and 170 healthy postmenopausal women were enrolled in the study. Serumβ-catenin, OPG, RANKL, and sclerostin levels were measured by enzyme-linked immunosorbent assay. Bone status was assessed by measuring bone mineral density and bone turnover markers. Estradiol levels were also detected.Results. Serumβ-catenin levels were lower in postmenopausal osteoporotic women compared to nonosteoporotic postmenopausal women (26.26±14.81versus39.33±5.47 pg/mL,P<0.001). Serumβ-catenin was positively correlated with osteoprotegerin (r=0.232,P<0.001) and negatively correlated with the ratio of RANKL/OPG, body mass index, and sclerostin (r=-0.128,P=0.005;r=-0.117,P=0.010;r=-0.400,P<0.001, resp.) in patients with postmenopausal osteoporosis.Conclusion. The results indicate that lower serumβ-catenin and concomitantly higher ratio of RANKL/OPG may be involved in the pathogenesis of postmenopausal osteoporosis. Functional communication between RANKL/RANK/OPG system and Wnt pathways plays an important role in postmenopausal osteoporosis.

The collagen turnover markers PICP and ICTP fail to predict bone turnover in postmenopausal osteoporosis

Bone ◽  
1995 ◽  
Vol 16 (6) ◽  
pp. 683
Author(s):  
M. France ◽  
S. Bowles ◽  
A. Davis ◽  
M.T.A. Rehman ◽  
P.L. Selby ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Postmenopausal Osteoporosis ◽  
Collagen Turnover ◽  
Turnover Markers

scholarly journals Association between bone turnover rate and bone microarchitecture in men: The STRAMBO study

2010 ◽  
Vol 25 (11) ◽  
pp. 2313-2323 ◽  
Author(s):  
Ali Chaitou ◽  
Stephanie Boutroy ◽  
Nicolas Vilayphiou ◽  
Françoise Munoz ◽  
Pierre D Delmas ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Turnover Rate ◽  
Bone Microarchitecture

scholarly journals Postmenopausal osteoporosis treatment with antiresorptives: Effects of discontinuation or long-term continuation on bone turnover and fracture risk-a perspective

2012 ◽  
Vol 27 (5) ◽  
pp. 963-974 ◽  
Author(s):  
Steven Boonen ◽  
Serge Ferrari ◽  
Paul D Miller ◽  
Erik F Eriksen ◽  
Philip N Sambrook ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Fracture Risk ◽  
Postmenopausal Osteoporosis ◽  
Osteoporosis Treatment
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