Activation of NF-κB in B cell receptor signaling through Bruton’s tyrosine kinase-dependent phosphorylation of IκB-α

Marilena Pontoriero; Giuseppe Fiume; Eleonora Vecchio; Annamaria de Laurentiis; Francesco Albano; Enrico Iaccino; Selena Mimmi; Antonio Pisano; Valter Agosti; Emilia Giovannone; Annalisa Altobelli; Carmen Caiazza; Massimo Mallardo; Giuseppe Scala; Ileana Quinto

doi:10.1007/s00109-019-01777-x

Activation of NF-κB in B cell receptor signaling through Bruton’s tyrosine kinase-dependent phosphorylation of IκB-α

Journal of Molecular Medicine ◽

10.1007/s00109-019-01777-x ◽

2019 ◽

Vol 97 (5) ◽

pp. 675-690 ◽

Cited By ~ 10

Author(s):

Marilena Pontoriero ◽

Giuseppe Fiume ◽

Eleonora Vecchio ◽

Annamaria de Laurentiis ◽

Francesco Albano ◽

...

Keyword(s):

Tyrosine Kinase ◽

B Cell ◽

Cell Receptor ◽

B Cell Receptor ◽

Bruton’S Tyrosine Kinase ◽

Receptor Signaling ◽

Bruton's Tyrosine Kinase ◽

B Cell Receptor Signaling ◽

Cell Receptor Signaling

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Cutting Edge: CD40 Engagement Eliminates the Need for Bruton’s Tyrosine Kinase in B Cell Receptor Signaling for NF-κB

The Journal of Immunology ◽

10.4049/jimmunol.170.6.2806 ◽

2003 ◽

Vol 170 (6) ◽

pp. 2806-2810 ◽

Cited By ~ 29

Author(s):

Takuya Mizuno ◽

Thomas L. Rothstein

Keyword(s):

Tyrosine Kinase ◽

B Cell ◽

Cell Receptor ◽

B Cell Receptor ◽

Cutting Edge ◽

Bruton’S Tyrosine Kinase ◽

Receptor Signaling ◽

Bruton's Tyrosine Kinase ◽

B Cell Receptor Signaling ◽

Cell Receptor Signaling

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Bruton's tyrosine kinase inhibition induces rewiring of proximal and distal B‐cell receptor signaling in mice

European Journal of Immunology ◽

10.1002/eji.202048968 ◽

2021 ◽

Author(s):

Jasper Rip ◽

Marjolein J.W. Bruijn ◽

Stefan F.H. Neys ◽

Simar Pal Singh ◽

Jonas Willar ◽

...

Keyword(s):

Tyrosine Kinase ◽

B Cell ◽

Cell Receptor ◽

B Cell Receptor ◽

Receptor Signaling ◽

Bruton's Tyrosine Kinase ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition ◽

B Cell Receptor Signaling ◽

Cell Receptor Signaling

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hCMV IE Promoter is responsive to B cell receptor signaling in a Bruton’s tyrosine kinase dependent manner: caution in their use as internal controls

Analytical Biochemistry ◽

10.1016/s0003-2697(02)00299-3 ◽

2002 ◽

Vol 309 (2) ◽

pp. 315-317

Author(s):

Shengli Hao ◽

Avery August

Keyword(s):

Tyrosine Kinase ◽

B Cell ◽

Cell Receptor ◽

Internal Controls ◽

B Cell Receptor ◽

Dependent Manner ◽

Receptor Signaling ◽

Bruton's Tyrosine Kinase ◽

B Cell Receptor Signaling ◽

Cell Receptor Signaling

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Ability of Bruton’s Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling

Molecular Pharmacology ◽

10.1124/mol.116.107037 ◽

2017 ◽

Vol 91 (3) ◽

pp. 208-219 ◽

Cited By ~ 42

Author(s):

Andrew T. Bender ◽

Anna Gardberg ◽

Albertina Pereira ◽

Theresa Johnson ◽

Yin Wu ◽

...

Keyword(s):

Tyrosine Kinase ◽

B Cell ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Cell Receptor ◽

Fc Receptor ◽

B Cell Receptor ◽

Receptor Signaling ◽

B Cell Receptor Signaling ◽

Cell Receptor Signaling

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Faculty Opinions recommendation of Ablation of CD22 in ligand-deficient mice restores B cell receptor signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1029979.351430 ◽

2005 ◽

Author(s):

Marcus Clark

Keyword(s):

B Cell ◽

Cell Receptor ◽

B Cell Receptor ◽

Receptor Signaling ◽

B Cell Receptor Signaling ◽

Deficient Mice ◽

Cell Receptor Signaling

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Faculty Opinions recommendation of Targeting B-Cell receptor signaling for anticancer therapy: the Bruton's tyrosine kinase inhibitor ibrutinib induces impressive responses in B-cell malignancies.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718490094.793497269 ◽

2014 ◽

Author(s):

Stephan Stilgenbauer

Keyword(s):

Tyrosine Kinase ◽

B Cell ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Cell Receptor ◽

Anticancer Therapy ◽

B Cell Receptor ◽

B Cell Malignancies ◽

B Cell Receptor Signaling ◽

Cell Receptor Signaling

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Faculty Opinions recommendation of Inhibition of B cell receptor signaling by ibrutinib in primary CNS lymphoma.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727663539.793562617 ◽

2019 ◽

Author(s):

Corrado Girmenia

Keyword(s):

B Cell ◽

Primary Cns Lymphoma ◽

Cell Receptor ◽

B Cell Receptor ◽

Cns Lymphoma ◽

Receptor Signaling ◽

B Cell Receptor Signaling ◽

Cell Receptor Signaling

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Pathogenic B‐cell receptor signaling in lymphoid malignancies: New insights to improve treatment

Immunological Reviews ◽

10.1111/imr.12792 ◽

2019 ◽

Vol 291 (1) ◽

pp. 190-213 ◽

Cited By ~ 16

Author(s):

Ryan M. Young ◽

James D. Phelan ◽

Wyndham H. Wilson ◽

Louis M. Staudt

Keyword(s):

B Cell ◽

Cell Receptor ◽

B Cell Receptor ◽

Receptor Signaling ◽

Lymphoid Malignancies ◽

Improve Treatment ◽

B Cell Receptor Signaling ◽

Cell Receptor Signaling

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Depletion of Hsp90β Induces Multiple Defects in B Cell Receptor Signaling

Journal of Biological Chemistry ◽

10.1074/jbc.m600891200 ◽

2006 ◽

Vol 281 (24) ◽

pp. 16361-16369 ◽

Cited By ~ 19

Author(s):

Fumika Shinozaki ◽

Michiko Minami ◽

Tomoki Chiba ◽

Miho Suzuki ◽

Katsuhiko Yoshimatsu ◽

...

Keyword(s):

B Cell ◽

Cell Receptor ◽

B Cell Receptor ◽

Receptor Signaling ◽

Multiple Defects ◽

B Cell Receptor Signaling ◽

Cell Receptor Signaling

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B-cell receptor signaling in chronic lymphocytic leukemia leans on Lyn

Leukemia & Lymphoma ◽

10.3109/10428194.2012.754097 ◽

2013 ◽

Vol 54 (6) ◽

pp. 1125-1126 ◽

Cited By ~ 2

Author(s):

Yair Herishanu ◽

Aaron Polliack

Keyword(s):

Chronic Lymphocytic Leukemia ◽

B Cell ◽

Cell Receptor ◽

B Cell Receptor ◽

Lymphocytic Leukemia ◽

Receptor Signaling ◽

B Cell Receptor Signaling ◽

Cell Receptor Signaling

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