scholarly journals Fasting serum levels of ferritin are associated with impaired pancreatic beta cell function and decreased insulin sensitivity: a population-based study

Diabetologia ◽  
2014 ◽  
Vol 58 (3) ◽  
pp. 523-533 ◽  
Author(s):  
Linéa Bonfils ◽  
Christina Ellervik ◽  
Nele Friedrich ◽  
Allan Linneberg ◽  
Camilla H. Sandholt ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Serum Levels ◽  
Population Based ◽  
Fasting Serum ◽  
Population Based Study ◽  
Pancreatic Beta Cell Function

Effect of troglitazone on insulin sensitivity and pancreatic beta-cell function in women at high risk for NIDDM

Diabetes ◽  
1996 ◽  
Vol 45 (11) ◽  
pp. 1572-1579 ◽  
Author(s):  
K. Berkowitz ◽  
R. Peters ◽  
S. L. Kjos ◽  
J. Goico ◽  
A. Marroquin ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
High Risk ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Pancreatic Beta Cell Function

scholarly journals OR31-6 Insulin Sensitivity and Pancreatic Beta-Cell Function in Patients with Primary Aldosteronism

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Shivraj Grewal ◽  
Andin Fosam ◽  
Liam Chalk ◽  
Arjun Deven ◽  
Mari Suzuki ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Beta Cell ◽  
Primary Aldosteronism ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Pancreatic Beta Cell Function

scholarly journals Is Serum Zinc Associated with Pancreatic Beta Cell Function and Insulin Sensitivity in Pre-Diabetic and Normal Individuals? Findings from the Hunter Community Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e83944 ◽  
Author(s):  
Khanrin P. Vashum ◽  
Mark McEvoy ◽  
Abul Hasnat Milton ◽  
Md. Rafiqul Islam ◽  
Stephen Hancock ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Serum Zinc ◽  
Community Study ◽  
Normal Individuals ◽  
Pancreatic Beta Cell Function

[I10W]tigerinin-1R enhances both insulin sensitivity and pancreatic beta cell function and decreases adiposity and plasma triglycerides in high-fat mice

2015 ◽  
Vol 53 (2) ◽  
pp. 303-315 ◽  
Author(s):  
Dinesh K. Srinivasan ◽  
Opeolu O. Ojo ◽  
Bosede O. Owolabi ◽  
J. Michael Conlon ◽  
Peter R. Flatt ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
High Fat ◽  
Plasma Triglycerides ◽  
Pancreatic Beta Cell Function

scholarly journals Increased insulin sensitivity and diminished pancreatic beta-cell function in DNA repair deficient Ercc1 mice

Metabolism ◽  
2021 ◽  
Vol 117 ◽  
pp. 154711
Author(s):  
Ana P. Huerta Guevara ◽  
Sara J. McGowan ◽  
Melissa Kazantzis ◽  
Tania Rozgaja Stallons ◽  
Tokio Sano ◽  
...  
Keyword(s):  
Dna Repair ◽  
Insulin Sensitivity ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Pancreatic Beta Cell Function

scholarly journals Effects of Lean Beef Intake, as Part of a Healthful Dietary Pattern, on Cardiometabolic Risk Markers in Subjects at Risk for Diabetes Mellitus: a Controlled Feeding Trial (FS18-02-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Kevin Maki ◽  
Orsolya Palacios ◽  
Meredith Wilcox ◽  
Mary Dicklin ◽  
Marjorie Bell ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Risk Markers ◽  
Lean Beef ◽  
Ldl Subfractions ◽  
Cardiometabolic Markers ◽  
Pancreatic Beta Cell Function

Abstract Objectives To assess and compare the effects of two diets low in saturated fatty acids (SFA): a United States Department of Agriculture (USDA) healthy US-style eating pattern (USDA diet) and a similar diet containing 150 g/d of lean beef in place of refined starches and added sugars (USDA-LB), on insulin sensitivity and other cardiometabolic markers in adults at-risk for type 2 diabetes (T2D). Methods This randomized, controlled crossover trial included two screening visits, a baseline visit, and two 28-d diet periods, separated by a 2-week washout. Thirty-three subjects (7 men, 26 women) provided evaluable data for this analysis. All foods were provided for each 28-d period. At baseline and at the end of each diet condition, insulin sensitivity and pancreatic beta-cell function were assessed with a 50-min intravenous glucose tolerance test. Other risk markers evaluated included fasting lipoprotein lipids, particles and subfractions, apolipoproteins A1 and B, homeostasis model assessment of fasting insulin sensitivity and beta-cell function, and high-sensitivity C-reactive protein. Results Baseline values and responses for selected variables are shown in the Table. Neither the USDA nor the USDA-LB diets had significant effects on insulin sensitivity or pancreatic beta-cell function; however, both produced a significant (P < 0.05) decrease in mean high-density lipoprotein cholesterol (HDL-C) versus baseline. The USDA diet also significantly (P < 0.05) reduced median non-HDL-C and mean total cholesterol (total-C) compared to baseline, but the response did not differ significantly from that of the USDA-LB diet. A shift toward larger and more buoyant LDL subfractions compared to the USDA diet (P = 0.007) and baseline (P < 0.05) occurred with the USDA-LB diet. No other significant differences were observed in carbohydrate or lipid metabolism and assessed parameters. Conclusions Intake of a low-SFA, USDA healthy US-style diet lowered total-C, non-HDL-C, and HDL-C compared with baseline. Inclusion of 150 g/d of lean beef did not adversely affect insulin sensitivity and related cardiometabolic markers compared with the USDA healthy diet and produced a shift toward larger, more buoyant LDL subfractions. Funding Sources Funded by The Beef Checkoff. Supporting Tables, Images and/or Graphs

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