Acute liver effects, disposition and metabolic fate of [14C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J mice

Kathryn Pickup; Scott Martin; Elizabeth A. Partridge; Huw B. Jones; Jonathan Wills; Tim Schulz-Utermoehl; Alan McCarthy; Alison Rodrigues; Chris Page; Kerry Ratcliffe; Sunil Sarda; Ian D. Wilson

doi:10.1007/s00204-016-1894-5

Acute liver effects, disposition and metabolic fate of [14C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J mice

Archives of Toxicology ◽

10.1007/s00204-016-1894-5 ◽

2016 ◽

Vol 91 (7) ◽

pp. 2643-2653 ◽

Cited By ~ 3

Author(s):

Kathryn Pickup ◽

Scott Martin ◽

Elizabeth A. Partridge ◽

Huw B. Jones ◽

Jonathan Wills ◽

...

Keyword(s):

Oral Administration ◽

Metabolic Fate ◽

Fenclozic Acid

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Metabolic fate of clopidol after repeated oral administration to rabbits

Journal of Agricultural and Food Chemistry ◽

10.1021/jf60198a052 ◽

1975 ◽

Vol 23 (2) ◽

pp. 269-274 ◽

Cited By ~ 3

Author(s):

Brian D. Cameron ◽

L. F. Chasseaud ◽

David R. Hawkins

Keyword(s):

Oral Administration ◽

Metabolic Fate

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The metabolic fate of fenclozic acid in chimeric mice with a humanized liver

Archives of Toxicology ◽

10.1007/s00204-018-2274-0 ◽

2018 ◽

Vol 92 (9) ◽

pp. 2819-2828 ◽

Cited By ~ 2

Author(s):

Anja Ekdahl ◽

Lars Weidolf ◽

Matthew Baginski ◽

Yoshio Morikawa ◽

Richard A. Thompson ◽

...

Keyword(s):

Chimeric Mice ◽

Metabolic Fate ◽

Fenclozic Acid

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Metabolic Fate of YM992. Absorption, Distribution, Excretion and Metabolic Fingerprinting after a Single Oral Administration of 14C-YM992 to Rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.14.371 ◽

1999 ◽

Vol 14 (5) ◽

pp. 371-384

Author(s):

Takuya SONODA ◽

Eiji NAKAMURA ◽

Kiyoshi NOGUCHI ◽

Takashi WATANABE ◽

Saburo HIGUCHI

Keyword(s):

Oral Administration ◽

Metabolic Fingerprinting ◽

Metabolic Fate ◽

Single Oral Administration

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Studies on the Metabolic Fate of SS320A. (3): Absorption, Metabolism and Excretion of 14C-SS320A after Single Oral Administration in Dogs.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.12.525 ◽

1997 ◽

Vol 12 (5) ◽

pp. 525-530

Author(s):

Toshihiro KOGURE ◽

Rie IKEDA ◽

Motohiro SUZUKI ◽

Takayuki OIKAWA ◽

Yoshio ESUMI ◽

...

Keyword(s):

Oral Administration ◽

Metabolic Fate ◽

Single Oral Administration

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The metabolic fate of [14C]-fenclozic acid in the hepatic reductase null (HRN) mouse

Xenobiotica ◽

10.3109/00498254.2013.866299 ◽

2013 ◽

Vol 44 (2) ◽

pp. 164-173 ◽

Cited By ~ 8

Author(s):

Kathryn Pickup ◽

Jonathan Wills ◽

Alison Rodrigues ◽

Huw B. Jones ◽

Chris Page ◽

...

Keyword(s):

Metabolic Fate ◽

Fenclozic Acid

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Studies on the Metabolic Fate of Pramipexole (SND 919 CL2Y). (I). Absorption, Distribution and Excretion after a Single Oral Administration to Rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.14.300 ◽

1999 ◽

Vol 14 (4) ◽

pp. 300-308

Author(s):

Kazutoshi YOKOYAMA ◽

Yoko OIWA ◽

Rumi IMANISHI ◽

Makoto SHIMASAKI ◽

Wataru KISHIMOTO ◽

...

Keyword(s):

Oral Administration ◽

Metabolic Fate ◽

Single Oral Administration ◽

Snd 919

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Absorption, disposition, metabolic fate and elimination of the anti-epileptic drug lacosamide in humans: mass balance following intravenous and oral administration

European Journal of Drug Metabolism and Pharmacokinetics ◽

10.1007/s13318-012-0093-x ◽

2012 ◽

Vol 37 (4) ◽

pp. 241-248 ◽

Cited By ~ 32

Author(s):

Willi Cawello ◽

Hilmar Boekens ◽

Rainer Bonn

Keyword(s):

Oral Administration ◽

Mass Balance ◽

Metabolic Fate ◽

Anti Epileptic Drug ◽

Intravenous And Oral Administration

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Studies on the Metabolic Fate of Azuletil Sodium. (VI). Distribution of Radioactivity in Gastric tissues after Oral Administration to Rats with Acetic Acid-Induced Gastric Ulcer.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.5.845 ◽

1990 ◽

Vol 5 (6) ◽

pp. 845-851

Author(s):

Masao SATO ◽

Hiroaki SUZAKA ◽

Akira TOMIYAMA ◽

Hiroshi MIYAZAKI

Keyword(s):

Acetic Acid ◽

Gastric Ulcer ◽

Oral Administration ◽

Metabolic Fate

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Studies on the Metabolic Fate of NK-104, a New Inhibitor of HMG-CoA Reductase. (3). Foeto-placental Transfer and Mammary Excretion after Oral Administration in Rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.13.508 ◽

1998 ◽

Vol 13 (5) ◽

pp. 508-515 ◽

Cited By ~ 1

Author(s):

Hideki FUJINO ◽

Shigeru MORIKAWA ◽

Hiroyasu KANDA ◽

Hideki KIMATA

Keyword(s):

Oral Administration ◽

Placental Transfer ◽

Metabolic Fate ◽

Hmg Coa Reductase ◽

Coa Reductase

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Metabolic Fate of a Novel Antiulcer Agent, T-593. (III). Blood Concentration, Distribution, Metabolism, Excretion and Effects on Hepatic Drug Metabolizing Enzyme System after Repeated Oral Administration to Rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.13.459 ◽

1998 ◽

Vol 13 (5) ◽

pp. 459-471

Author(s):

Makoto ONODA ◽

Takumi KADOTA ◽

Shinsuke OOYAMA ◽

Hiroko MATSUTANI ◽

Hiroshi SAKAI ◽

...

Keyword(s):

Oral Administration ◽

Blood Concentration ◽

Concentration Distribution ◽

Enzyme System ◽

Metabolic Fate ◽

Hepatic Drug ◽

Drug Metabolizing Enzyme ◽

Antiulcer Agent ◽

Metabolizing Enzyme

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