Therapeutic activity of the topoisomerase I inhibitor J-107088 [6- N -(1-hydroxymethyla-2-hydroxy) ethylamino-12,13-dihydro-13-(β- D -gluco pyranosyl)- 5H -indolo[2,3- a ]-pyrrolo[3,4- c ]-carbazole-5,7( 6H )-dione] against pediatric and adult central nervous system tumor xenografts

2001 ◽  
Vol 48 (3) ◽  
pp. 250-254 ◽  
Author(s):  
Christina Cavazos ◽  
Stephen Keir ◽  
Tomoko Yoshinari ◽  
Darell Bigner ◽  
Henry Friedman
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Topoisomerase I ◽  
Central Nervous System Tumor ◽  
Therapeutic Activity ◽  
Tumor Xenografts ◽  
Adult Central Nervous System ◽  
Topoisomerase I Inhibitor ◽  
System Tumor

Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumor xenografts

1994 ◽  
Vol 34 (2) ◽  
pp. 171-174 ◽  
Author(s):  
Henry S. Friedman ◽  
Peter J. Houghton ◽  
S. Clifford Schold ◽  
Stephen Keir ◽  
Darell D. Bigner
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Tumor ◽  
Tumor Xenografts ◽  
Adult Central Nervous System ◽  
System Tumor

Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumor xenografts

1994 ◽  
Vol 34 (2) ◽  
pp. 171-174 ◽  
Author(s):  
Henry S. Friedman? ◽  
Peter J. Houghton ◽  
S. Clifford Schold ◽  
Stephen Keir ◽  
Darell D. Bigner
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Tumor ◽  
Tumor Xenografts ◽  
Adult Central Nervous System ◽  
System Tumor

Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents

1998 ◽  
Vol 41 (6) ◽  
pp. 485-490 ◽  
Author(s):  
Claire A. Coggins ◽  
Gertrude B. Elion ◽  
Peter J. Houghton ◽  
C. Bradley Hare ◽  
O. Michael Colvin ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Alkylating Agents ◽  
Central Nervous System Tumor ◽  
Tumor Xenografts ◽  
System Tumor

scholarly journals Central liponeurocytoma: Case report and review of literature

2012 ◽  
Vol 01 (01) ◽  
pp. 083-085 ◽  
Author(s):  
Pankaj Ailawadhi ◽  
M.C. Sharma ◽  
A.K. Mahapatra ◽  
P. Sarat Chandra
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Tumor Classification ◽  
Central Nervous System Tumor ◽  
The Central Nervous System ◽  
Cerebellar Liponeurocytoma ◽  
Classification Of Tumors ◽  
System Tumor ◽  
Well Differentiated ◽  
Glioneuronal Tumors

Abstract Cerebellar liponeurocytoma consists of well-differentiated neurons with the cytology of neurocytes in addition to a population of lipidized cells. Hence it is biphasic in appearance and has been included in the category of glioneuronal tumors of the central nervous system by the WHO working group on the Classification of Tumors of the Nervous System. However, liponeurocytoma is not exclusive to the cerebellar or fourth ventricular location. Since its inclusion in the central nervous system tumor classification, nine cases with similar histological and immunohistochemical features have also been described in the lateral ventricles. We describe here such a lateral ventricular tumour in a 30-year-old woman, characteristically showing divergent glio-neuronal differentiation and lipidized neoplastic cells. Therefore, we suggest that future WHO tumor classification should consider that liponeurocytomas are not entirely restricted to the cerebellum and henceforth change of nomenclature might be considered, as also pointed out by other authors.

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