Antioxidant capacity, lipid peroxidation, and lipid composition changes during long-term and short-term thermal acclimation in Daphnia

2017 ◽  
Vol 187 (8) ◽  
pp. 1091-1106 ◽  
Author(s):  
Bret L. Coggins ◽  
John W. Collins ◽  
Kailea J. Holbrook ◽  
Lev Y. Yampolsky
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Capacity ◽  
Lipid Composition ◽  
Thermal Acclimation ◽  
Short Term ◽  
Composition Changes

scholarly journals Effect of Melatonin Intake on Oxidative Stress Biomarkers in Male Reproductive Organs of Rats under Experimental Diabetes

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Marina G. Gobbo ◽  
Carolina F. Pereira Costa ◽  
Danilo G. Humberto Silva ◽  
Eduardo A. de Almeida ◽  
Rejane M. Góes
Keyword(s):  
Lipid Peroxidation ◽  
Fold Increase ◽  
Reproductive Organs ◽  
System Response ◽  
Short Term ◽  
Oxidative Stress Biomarkers ◽  
Melatonin Treatment ◽  
Male Reproductive Organs ◽  
Gpx Activity

This study investigated the antioxidant system response of male reproductive organs during early and late phases of diabetes and the influence of melatonin treatment. Melatonin was administered to five-week-old Wistar rats throughout the experiment, in drinking water (10 μg/kg b.w). Diabetes was induced at 13 weeks of age by streptozotocin (4.5 mg/100 g b.w., i.p.) and animals were euthanized with 14 or 21 weeks old. Activities of catalase (CAT), glutathione-S-transferase (GST), glutathione peroxidase (GPx), and lipid peroxidation were evaluated in prostate, testis, and epididymis. The enzymes activities and lipid peroxidation were not affected in testis and epididymis after one or eight weeks of diabetes. Prostate exhibited a 3-fold increase in GPx activity at short-term diabetes and at long-term diabetes there were 2- and 3-fold increase in CAT and GST, respectively (p≤0.01). Melatonin treatment to healthy rats caused a 47% increase in epididymal GPx activity in 14-week-old rats. In prostate, melatonin administration normalized GST activity at both ages and mitigated GPx at short-term and CAT at long-term diabetes. The testis and epididymis were less affected by diabetes than prostate. Furthermore, melatonin normalized the enzymatic disorders in prostate demonstrating its effective antioxidant role, even at low dosages.

scholarly journals ENHANCEMENT OF FRESHMEN’S ADAPTATION TO HIGH SCHOOL

2019 ◽  
Vol 19 (S1) ◽  
pp. 68-76
Author(s):  
A Nikulina
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Selenium Concentration ◽  
Antioxidant Protection ◽  
Short Term ◽  
Biochemical Indicators ◽  
Second Year ◽  
Antioxidant Protection System ◽  
Deficient Area

Aim. The article deals with studying the effect of a complex selenium-containing compound and physio disease-preventing means on the enhancement of biochemical indicators in freshmen living in a selenium-deficient area. Materials and methods. We conducted 12 longitudinal studies with the students of the first and second year studying at Chuvash Universities (n = 180). Selenium concentration in blood serum was established with the help of fluorometry performed according to Golubkina’s interpretation (Fluorat-02-2M). The activity of lipid peroxidation (c.u.) and antioxidant system (c.u.) was studied using induced chemiluminescence (Biochemiluminometer БХЛ-06). Results. The use of Selenes+ together with a disease-preventing photochrome session is accompanied by antioxidant, metabolic, and hemopoietic effects manifested in the increase of antioxidant activity and selenium concentration by 31.1 and 62.5 %, respectively, and the decrease of lipid peroxidation by 4.1–19.7 % compared to control values. The use of Selenes+ together with exercises contributes to less pronounced stress in the cardiovascular system both during the study and exam periods. Conclusion. Therefore, selenium correction of body adaptation with respect to a biogeochemical specifics of a region normalizes the balance between prooxidant and antioxidant elements of the antioxidant protection system and provides an accelerated shift from short-term to long-term adaptation.

121. SHORT TERM XENOBIOTIC EXPOSURE COMPROMISES LONG TERM OOCYTE VIABILITY

2010 ◽  
Vol 22 (9) ◽  
pp. 39
Author(s):  
A. P. Sobinoff ◽  
V. Pye ◽  
B. Nixon ◽  
S. D. Roman ◽  
E. A. McLaughlin
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Quiescent State ◽  
Free Oxygen Radicals ◽  
Dependent Manner ◽  
Short Term ◽  
Primordial Follicles ◽  
Xenobiotic Exposure ◽  
Dose Dependent

Mammalian females are born with a finite number of non-renewing primordial follicles, the majority of which remain in a quiescent state for many years. These follicles serve as the primary source of all developing oocytes in the ovary, and cannot be regenerated post fetal development. Due to their non-renewing nature, these “resting” oocytes are particularly vulnerable to environmental and toxic insults, especially to those which are capable of inducing oxidative stress. Recent evidence suggests that certain synthetic chemical compounds, known as xenobiotics, have the potential to generate oxidative stress through the production of free oxygen radicals (ROS) as a byproduct of the cell’s detoxification process. Given the redox sensitive nature of the mammalian oocyte, we hypothesise that xenobiotic exposure may have adverse effects on long term oocyte viability. In this study, we attempted to identify the effects of short term xenobiotic exposure on long term oocyte viability. Female Swiss neonatal mice (day 4) were administered 7 daily consecutive doses of 4-Vinylcyclohexene diepoxide (40mg/kg/daily; 80mg/kg/daily) Methoxychlor (50mg/kg/daily; 100mg/kg/daily) or Menadione (7.5mg/kg/daily; 15mg/kg/daily). Mice were then superovulated at 6wks and their oocytes collected for analysis. Sperm-egg fusion assays revealed a significant decrease (P < 0.01) in sperm egg binding (1.4–7 fold) and fusion (4–20 fold) in a dose dependent manner for all three xenobiotic treatments in vivo, signifying a decrease in oocyte membrane fluidity. Follow-up lipid peroxidation analysis on xenobiotic cultured oocytes also showed a significant (P < 0.01) dose dependent increase (1.3–2.5 fold) in membrane lipid peroxidation for each xenobiotic compared to the control. These results provide some of the first evidence of short term xenobiotic exposure causing long term oocyte dysfunction, possibly interfering with the fluidity and/or elasticity of the oocyte plasma membrane through xenobiotic ROS induced lipid peroxidation.

scholarly journals Adaptive Response of a Native Mediterranean Grapevine Cultivar Upon Short-Term Exposure to Drought and Heat Stress in the Context of Climate Change

Agronomy ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 249 ◽  
Author(s):  
Nikolaos Tzortzakis ◽  
Antonios Chrysargyris ◽  
Aziz Aziz
Keyword(s):  
Climate Change ◽  
Lipid Peroxidation ◽  
Heat Stress ◽  
Stomatal Conductance ◽  
Antioxidant Capacity ◽  
Stomatal Closure ◽  
Total Phenolic ◽  
Short Term ◽  
Short Term Exposure ◽  
The Impact

The impact of climate change on viticulture is of major importance. Several international and indigenous grapevine cultivars have been examined for their adaptive performance to drought and heat stresses. However, the underlying physiological mechanisms are not well known. In the present study we examined the short-term effects of light and moderate drought stress (DS) as well as heat stress (HS) on physiological and biochemical attributes in two grapevine cultivars: Chardonnay (international) and Xynisteri, an indigenous adapted to the specific Cypriot microclimate. Xynisteri plants exhibited decreasing leaf stomatal conductance and photosynthetic rate as well as increasing total phenols and antioxidant capacity under DS conditions. These reactions were concomitant to a rapid accumulation of hydrogen peroxide and lipid peroxidation in leaves, associated to an increase of the antioxidant superoxide dismutase activity. However, Chardonnay plants did not exhibit the same responses as Xynisteri against DS (i.e., stomatal closure, total phenolics and antioxidants) over the first four days. Additionally, Chardonnay showed leaf damage with increased lipid peroxidation levels and activation of catalase and peroxidase. Interestingly, HS increased leaf stomatal conductance and decreased total phenolic content, flavonoids and antioxidant capacity in Chardonnay after 20 d of stress. In both cultivars, HS had milder effects compared to DS, and again Xynisteri showed better performance than Chardonnay in terms of damage index and antioxidative activities. Overall, Xynisteri adaptation to DS and HS was higher than that of Chardonnay, and both cultivars reacted more to the short-term DS than to HS. Although the Xynisteri performances under stress conditions provide an important resource for adaptation to stressful conditions, the impacts on earliness, yield and grape quality remain to be explored.

Solute profiles in soils, weathering gradients and exchange equilibrium/disequilibrium

2008 ◽  
Vol 72 (1) ◽  
pp. 149-153 ◽  
Author(s):  
A. F. White ◽  
M. S. Schulz ◽  
D. A. Stonestrom ◽  
D. V. Vivit ◽  
J. Fitzpatrick ◽  
...  
Keyword(s):  
Sea Water ◽  
Exchange Equilibrium ◽  
Soil Composition ◽  
Short Term ◽  
Soil Chronosequence ◽  
Weathering Rates ◽  
Marine Terraces ◽  
Spatial And Temporal Changes ◽  
Composition Changes

AbstractThe spatial and temporal changes in hydrology and pore water elemental and 87/86Sr compositions were used to determine contemporary weathering rates in a 65 to 226 ky old soil chronosequence formed from granitic sediments deposited on marine terraces along coastal California. Cl-corrected Na, K and Si increased with depth denoting inputs from the weathering of plagioclase and K-feldspar. Solute 87/86Sr exhibited progressive mixing of sea water-dominated precipitation with inputs from less radiogenic plagioclase. Linear approximations to these weathering gradients were used to determine plagioclase weathering rates of between 0.38 and 8.9x10-15 moles m-2 s-1. The lack of corresponding weathering gradients for Ca and Sr indicated short-term equilibrium with the clay ion exchange pool which requires periodic resetting by natural perturbations to maintain continuity, in spite of soil composition changes reflecting the effects of long-term weathering.

scholarly journals Long-term, but not short-term high-fat diet induces fiber composition changes and impaired contractile force in mouse fast-twitch skeletal muscle

2017 ◽  
Vol 5 (7) ◽  
pp. e13250 ◽  
Author(s):  
Hiroaki Eshima ◽  
Yoshifumi Tamura ◽  
Saori Kakehi ◽  
Nagomi Kurebayashi ◽  
Takashi Murayama ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
High Fat Diet ◽  
Contractile Force ◽  
High Fat ◽  
Short Term ◽  
Fiber Composition ◽  
Fast Twitch ◽  
Composition Changes

Conceptual short-term memory (CSTM) supports core claims of Christiansen and Chater

2016 ◽  
Vol 39 ◽  
Author(s):  
Mary C. Potter
Keyword(s):  
Working Memory ◽  
Rapid Serial Visual Presentation ◽  
Language Comprehension ◽  
Short Term Memory ◽  
Visual Presentation ◽  
Long Term Memory ◽  
Short Term ◽  
Term Memory ◽  
Use Of Knowledge

AbstractRapid serial visual presentation (RSVP) of words or pictured scenes provides evidence for a large-capacity conceptual short-term memory (CSTM) that momentarily provides rich associated material from long-term memory, permitting rapid chunking (Potter 1993; 2009; 2012). In perception of scenes as well as language comprehension, we make use of knowledge that briefly exceeds the supposed limits of working memory.

Ultrastructural investigations of MDL 19,660-induced effects on the canine platelet and megakaryocyte

1990 ◽  
Vol 48 (3) ◽  
pp. 374-375
Author(s):  
D.E. Loudy ◽  
J. Sprinkle-Cavallo ◽  
J.T. Yarrington ◽  
F.Y. Thompson ◽  
J.P. Gibson
Keyword(s):  
Antidepressant Drug ◽  
Beagle Dogs ◽  
Long Term Effects ◽  
Short Term ◽  
Platelet Counts ◽  
Toxicological Studies ◽  
Induced Aggregation ◽  
Internal Architecture

Previous short term toxicological studies of one to two weeks duration have demonstrated that MDL 19,660 (5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3Hl, 2,4-triazole-3-thione), an antidepressant drug, causes a dose-related thrombocytopenia in dogs. Platelet counts started to decline after two days of dosing with 30 mg/kg/day and continued to decrease to their lowest levels by 5-7 days. The loss in platelets was primarily of the small discoid subpopulation. In vitro studies have also indicated that MDL 19,660: does not spontaneously aggregate canine platelets and has moderate antiaggregating properties by inhibiting ADP-induced aggregation. The objectives of the present investigation of MDL 19,660 were to evaluate ultrastructurally long term effects on platelet internal architecture and changes in subpopulations of platelets and megakaryocytes.Nine male and nine female beagle dogs were divided equally into three groups and were administered orally 0, 15, or 30 mg/kg/day of MDL 19,660 for three months. Compared to a control platelet range of 353,000- 452,000/μl, a doserelated thrombocytopenia reached a maximum severity of an average of 135,000/μl for the 15 mg/kg/day dogs after two weeks and 81,000/μl for the 30 mg/kg/day dogs after one week.

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