The impact of a meat- versus a vegetable-based diet on iron status in women of childbearing age with small iron stores

2007 ◽  
Vol 46 (8) ◽  
pp. 439-445 ◽  
Author(s):  
Inge Tetens ◽  
Karen M. Bendtsen ◽  
Marianne Henriksen ◽  
Annette K. Ersbøll ◽  
Nils Milman
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Loubna Belaid ◽  
Emmanuel Ochola ◽  
Pontius Bayo ◽  
George William Alii ◽  
Martin Ogwang ◽  
...  

Abstract Background Community participatory interventions mobilizing women of childbearing age are an effective strategy to promote maternal and child health. In 2017, we implemented this strategy in Gulu Northern Uganda. This study explored the perceived impact of this approach on women's capability. Methods We conducted a qualitative study based on three data collection methods: 14 in-depth individual interviews with participating women of childbearing age, five focus group discussions with female facilitators, and document analysis. We used the Sen capability approach as a conceptual framework and undertook a thematic analysis. Results Women adopted safe and healthy behaviors for themselves and their children. They were also able to respond to some of their family's financial needs. They reported a reduction in domestic violence and in mistreatment towards their children. The facilitators perceived improved communication skills, networking, self-confidence, and an increase in their social status. Nevertheless, the women still faced unfreedoms that deprived them of living the life they wanted to lead. These unfreedoms are related to their lack of access to economic opportunities and socio-cultural norms underlying gender inequalities. Conclusion To expand women's freedoms, we need more collective political actions to tackle gender inequalities and need to question the values underlying women's social status.


BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S93-S94
Author(s):  
Helen Muskett ◽  
Kirsty Bradley ◽  
Lauren Stott ◽  
William Moreton ◽  
Sarah Jones

AimsThe release of the Cumberlege Report in 2020 served as a reminder of the importance of informed consent for women when they are started on treatment that may affect their fertility or future pregnancies.Our aim was to evaluate current performance with regards to advice given to women of childbearing age around contraception, impacts of psychotropic medication on fertility and future pregnancies, and availability of preconception counselling.MethodStandard identified as NICE Guideline 192 (Antenatal and Postnatal Mental Health), sections 1.2 and 1.4.60 female inpatients were selected by looking at the most recent discharges prior to 03/11/2020 from 3 local acute adult wards. All females aged between 18 and 48 years were included.Electronic notes were reviewed for each patient. The discharge summary and last four ward round entries were reviewed, then key-word search of the patients’ records was performed using the terms “pregnan*”, “conception”, “contraception”, and “fertility”.The following information for each patient was documented in a spreadsheet:Discharge medicationIs there any discussion or advice around contraception?Have women taking antipsychotic medication been given advice regarding the possible impact on fertility?Has the potential impact of psychotropic medication on a future pregnancy been discussed?Has advice been given about the availability of preconception counselling should they plan a pregnancy in future?ResultOn discharge, a total of 33 women were taking one or more antipsychotics and 14 were prescribed a benzodiazepine. 24 women were discharged with antidepressants and 10 women were using a mood stabilising agent. 8 women were discharged without any psychotropic medication.Overall, 4 women received advice about contraception, and a further 8 women were already using contraception. The impact of taking an antipsychotic on fertility was not discussed with any patient. No women were advised about pre-conception counselling. The impact of taking psychotropic medication on a future pregnancy was discussed with one woman.ConclusionCurrent practice falls well below the standard set by NICE. Opportunities to inform women are being missed, and this has implications for the wellbeing of the patient and, potentially, future children.Action plan;Present findings at teaching.Deliver local teaching covering preconception counselling and the role of adult mental health teams when managing women of childbearing age.Produce a poster for inpatients wards and an information leaflet for women of childbearing age to aid with discussions.Create a poster for doctors’ offices to remind about NICE standards and documentation.Re-audit in 6 months.


Seizure ◽  
2020 ◽  
Vol 79 ◽  
pp. 8-13 ◽  
Author(s):  
Philippa Davies ◽  
Markus Reuber ◽  
Richard Grunewald ◽  
Stephen Howell ◽  
Jon Dickson ◽  
...  

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1279
Author(s):  
Ulrika Axling ◽  
Gunilla Önning ◽  
Maile A. Combs ◽  
Alemtsehay Bogale ◽  
Magnus Högström ◽  
...  

Iron is an essential micronutrient for oxygen transport and mitochondrial metabolism and is critical for physical performance. Compromised iron stores are more commonly found among athletes, and females are especially at risk. Iron deficiency is generally treated using oral iron supplements. However, only a small proportion of ingested iron is absorbed, necessitating higher intakes, which may result in adverse side effects, reduced compliance, and inefficient repletion of iron stores. The probiotic strain Lactobacillus plantarum 299v (Lp299v) significantly increases intestinal iron absorption in meal studies. The present study was conducted to explore the effects of 20 mg of iron with or without Lp299v on iron status, mood state, and physical performance. Fifty-three healthy non-anemic female athletes with low iron stores (ferritin < 30 μg/L) were randomized, and 39 completed the study. Intake of Lp299v with iron for four weeks increased ferritin levels more than iron alone (13.6 vs. 8.2 µg/L), but the difference between the groups was not significant (p = 0.056). The mean reticulocyte hemoglobin content increased after intake of Lp299v compared to control (1.5 vs. 0.82 pg) after 12 weeks, but the difference between the group was not significant (p = 0.083). The Profile of Mood States (POMS) questionnaire showed increased vigor with Lp299v vs. iron alone after 12 weeks (3.5 vs. 0.1, p = 0.015). No conclusive effects on physical performance were observed. In conclusion, Lp299v, together with 20 mg of iron, could result in a more substantial and rapid improvement in iron status and improved vigor compared to 20 mg of iron alone. A larger clinical trial is needed to further explore these findings as well as the impact of Lp299v on physical performance.


Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 1281-1281
Author(s):  
Corentin Orvain ◽  
Lydie Da Costa ◽  
Richard van Wijk ◽  
Serge Pissard ◽  
Veronique Picard ◽  
...  

Abstract Background: Hereditary stomatocytosis is an inherited disorder of the erythrocyte membrane responsible of chronic hemolytic anemia. Recent advances in the understanding of this group of diseases came from the identification of the molecular basis of this disorder. Mutations in the SLC4A1, FAM38A, RHAG, and SLC2A1 genes have been shown to cause different subtypes of hereditary stomatocytosis. Dehydrated hereditary stomatocytosis (DHSt) is due to mutations in the FAM38A gene coding for the mechanotransduction protein PIEZO1 and to the newly discovered mutations in the KCNN4 gene encoding the Gardos channel. It is important to recognize this entity and differentiate it from hereditary spherocytosis as patients with HSt develop severe and sometimes lethal thromboembolic complications following splenectomy. Also, some patients develop progressive and severe iron overload (IO) despite well compensated hemolysis and no or little transfusion requirement. It is unclear why patients have such different clinical features regarding hemolytic anemia and IO. We describe herein the impact of inherited and acquired modifiers of iron status on the phenotypic expression of DHSt. Patients & Methods: We describe four patients (3 related and 1 unrelated) with proven DHSt due to FAM38A mutations, who displayed varying degrees of iron load. Results: The four reported patients were referred to our specialized outpatient consultation (center of expertise on rare iron overload) for investigation. Their clinical, laboratory and radiological features are summarized in the Table. It is noteworthy that both index cases were initially referred for investigation of hyperferritinemia. Iron levels closely correlated with the degree of hemolysis and with the severity of the clinical complications. One female patient with severe iron overload suffered from chronic anemia, acute hemolytic episodes, and symptomatic gallstones requiring cholecystectomy while one male patient with severe iron overload suffered from a thrombotic event. The two other female patients with no or moderate iron overload had no or mild hemolysis. Genetic modifiers increasing iron stores, such as the presence of the HFE C282Y mutation, and possibly the gender (male), were accompanied with higher liver iron concentration, increased hemolysis and clinical manifestations. On the opposite, females with normal or low iron stores (iron deficiency anaemia (ID) due to gynecologic bleedings) displayed no or mild hemolytic manifestations. It is noteworthy that in the female with ID no clinical or biological manifestations of hemolysis and of stomatocytosis were found initially (normal specialized phenotypic tests). The diagnosis was made by genetic analyses. Restoration of the iron stores resulted in the appearance of biological signs of hemolysis. Conclusion: Iron overload or iron deficiency dramatically alter the clinical presentation of DHST due to PIEZO1 defects. The search for genetic or acquired causes of iron overload (or deficiency) is an important step in the evaluation of the clinical prognosis and the modulation of iron store may help in the management of the patients. Table Clinical, biological, and radiological characteristics of the 4 patients N: normal value; NA: not available; wt: wild-type; ID: iron deficiency Table. Clinical, biological, and radiological characteristics of the 4 patients. / N: normal value; NA: not available; wt: wild-type; ID: iron deficiency Disclosures Cartron: Roche: Consultancy, Honoraria; Celgene: Honoraria; Gilead: Honoraria; Jansen: Honoraria.


2016 ◽  
Vol 4 (1) ◽  
pp. 37
Author(s):  
Ulya Rohima Ammar

ABSTRACTPrimary dysmenorrhea was menstrual pain without any real abnormalities in genitals and could be a sign of reproductive system disorders. Prevalence of primary dysmenorrhea was quite high, but the lack of attention from the medical world, whereas primary dysmenorrhea can lead to decreased productivity and hinder daily activities. This  study  aimed  to  analyze  the  risk factors  of  primary  dysmenorrhea  in  Ploso  subdistrict  of Tambaksari Surabaya. The study was an observational analytic cross sectional design. Sampling was done by multistage cluster sampling. Respondents were 80 women of childbearing age 15-35 years old. Based on the results the prevalence of primary dysmenorrhea was at 71.3% . Most of the impact of primary dysmenorrhea that respondents perceived were declining productivity that is equal to 77.2%. Most of respondents not been examined primary dysmenorrhea to the doctor or midwife (84.2%) with the majority reason was respondents think that symptoms of primary dysmenorrhea perceived is reasonable (54.2%) . The highest proportion of respondents characteristics are aged 15-25 years (51.3%), had family history (52.5%), never given birth (60%), duration of menstruation 3-7 days (86%), age of menarche 12-13 years (53.8%), not did exercise (53.8%), had a normal nutritional status (38.8%), and severe stress (25%). The results of the bivariate analysis showed that there was a relationship between age and family history with primary dysmenorrhea, and there was no relationship between the experience of childbirth, length of menstruation, age of menarche, exercise habits, nutritional status, and state of stress with primary dysmenorrhea. The advice is to check primary dysmenorrhea to the doctor or midwife if find symptoms of primary dysmenorrhea to get treatment (psychotherapy or medication therapy), so that respondents could still work or do activities and productivity is not compromised. Keywords : primary dysmenorrhea , menstrual cramps, risk factors, women of childbearing age, reproduction


2011 ◽  
Vol 21 (6) ◽  
pp. 501-506 ◽  
Author(s):  
Diane M. DellaValle ◽  
Jere D. Haas

The objective of this study was to determine the impact of iron depletion without anemia on performance in a sample of female collegiate rowers at the beginning of a training season (August 2008, January 2009, and September 2009). One hundred sixty-five female collegiate rowers from 5 colleges and universities in central New York State participated in a screening of iron status. Blood hemoglobin (Hgb), serum ferritin (sFer), and soluble transferrin receptor were measured to determine prevalence of iron depletion and anemia. Rowers’ habitual moderate and vigorous physical activity, as well as their best time to complete a 2-km simulated race during the previous 3 months, were self-reported. Sixteen rowers (10%) were identified as anemic (Hgb <12.0 g/dl). Using a sFer cutoff of <20.0 μg/L, 30% (n = 44) of the nonanemic rowers were identified as iron depleted without anemia and reported 2-km times ~21 s slower (p < .004) than rowers with normal iron status. Given the high prevalence of iron depletion reported in this and other studies, screening for low iron stores at the start of a training program in female athletes involved in an endurance sport may be clinically useful. In this study, irondepleted rowers (sFer <20–25 μg/L) reported a decrease in performance time compared with those with normal iron stores.


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 905-905
Author(s):  
Gregory Sclama ◽  
Diego Rose

Abstract Objectives Dietary phytate is a potent inhibitor of zinc absorption. Phytate levels of cereals can be reduced by basic household processing techniques such as soaking, germinating, and fermenting. The objective of this study was to model the potential of such techniques to reduce the burden of zinc deficiency in Malawi, where high-phytate maize is a dietary staple. Methods Using nationally representative household consumption data and food composition tables, we estimated daily phytate and zinc intakes for individuals in Malawi. We then applied a mathematical model of zinc absorption based on total dietary zinc and phytate to calculate the apparent absorbed zinc for each individual. Using the Cut-Point method described by the Institute of Medicine, we determined the proportion of each physiological group with absorbed zinc below their mean requirements. We then simulated the reduction in dietary phytate resulting from maize processing and estimated the new burdens of zinc deficiency. We estimated the impact at various coverage levels and compared the results against an alternative model using zinc-biofortified maize. Results Nationally, 34% of females age 14–18 and 23% of females over age 18 were at risk of zinc deficiency. Only 13% of women of childbearing age met the zinc requirement for pregnancy, while less than 4% met the requirement for breastfeeding. The burden of zinc deficiency was highest in the South where maize intake was highest. The simulation of phytate reduction from household processing found that with 40% coverage, the proportion of at-risk females age 14–18 fell below 23%, while the proportion over age 18 fell to 14%. The potential benefits were greatest in the South, where the proportion of women at risk was reduced by over a third. Biofortification also reduced zinc deficiency, however the modeled impact of processing was greater than biofortification for all regions and subgroups. Conclusions Household food processing techniques may be an important strategy to reduce the burden of zinc deficiency among vulnerable women in Malawi. These techniques are low-cost and not widely practiced at present. Behavior change interventions to promote them must consider culture, gender norms, and drivers of food preference. Food-based approaches such as these should be given greater attention in nutrition and health policy and programming. Funding Sources None.


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