scholarly journals Etiologies of olfactory dysfunction in a pediatric population: based on a retrospective analysis of data from an outpatient clinic

2020 ◽  
Vol 277 (11) ◽  
pp. 3213-3216 ◽  
Author(s):  
Valentin Alexander Schriever ◽  
Thomas Hummel
Keyword(s):  
Retrospective Analysis ◽  
Outpatient Clinic ◽  
Pediatric Population ◽  
Population Based ◽  
Olfactory Dysfunction

scholarly journals Gynecologic Malignancies in Children and Adolescents: How Common is the Uncommon?

2021 ◽  
Vol 10 (4) ◽  
pp. 722
Author(s):  
Christoph Wohlmuth ◽  
Iris Wohlmuth-Wieser
Keyword(s):  
Pediatric Population ◽  
Age Groups ◽  
Germ Cell Tumors ◽  
Population Based ◽  
Prognostic Indicators ◽  
Gynecologic Malignancies ◽  
Kaplan Meier ◽  
Disease Stages ◽  
Malignant Germ Cell Tumors ◽  
Vaginal Neoplasms

The aim of this study is to assess the projected incidence and prognostic indicators of gynecologic malignancies in the pediatric population. In this population-based retrospective cohort study, girls ≤18 years with ovarian, uterine, cervical, vaginal and vulvar malignancies diagnosed between 2000 and 2016 were identified from the Surveillance, Epidemiology and End Results (SEER)-18 registry. The Kaplan–Meier method was used to analyze overall survival (OS). The age-adjusted annual incidence of gynecologic malignancies was 6.7 per 1,000,000 females, with neoplasms of the ovary accounting for 87.5%, vagina 4.5%, cervix 3.9%, uterus 2.5% and vulva 1.6% of all gynecologic malignancies. Malignant germ-cell tumors represented the most common ovarian neoplasm, with an increased incidence in children from 5–18 years. Although certain subtypes were associated with advanced disease stages, the 10-year OS rate was 96.0%. Sarcomas accounted for the majority of vaginal, cervical, uterine and vulvar malignancies. The majority of vaginal neoplasms were observed in girls between 0–4 years, and the 10-year OS rate was 86.1%. Overall, gynecologic malignancies accounted for 4.2% of all malignancies in girls aged 0–18 years and the histologic subtypes and prognosis differed significantly from patients in older age groups.

scholarly journals Smell and taste disorders in the UK: first experiences with a specialised smell and taste outpatient clinic

2014 ◽  
Vol 96 (5) ◽  
pp. 156-159 ◽  
Author(s):  
Carl Philpott
Keyword(s):  
Outpatient Clinic ◽  
Olfactory Dysfunction ◽  
Recent Survey ◽  
Olfactory Testing ◽  
The Usa ◽  
Taste Disorders ◽  
The Uk

Olfactory dysfunction is common, affecting 1–5% of those under the age of 60 1 and at least 20% of those aged more than 60 years. 2 In many UK centres, the approach to it is variable and routine olfactory testing is not performed, as noted by a recent survey of British ENT surgeons. 3 This is in contrast to Europe and the USA, where many specialist smell and taste centres already exist.

scholarly journals Did admissions caused by respiratory infections and asthma decrease during the COVID-19 pandemic?

2021 ◽  
Author(s):  
Zeynep Onay ◽  
Deniz Mavi ◽  
Yetkin Ayhan ◽  
Sinem Can Oksay ◽  
Gulay Bas ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Outpatient Clinic ◽  
Lower Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Respiratory Infections ◽  
Pediatric Population ◽  
Pediatric Intensive Care ◽  
Acute Bronchiolitis ◽  
Lower Respiratory Tract Infections ◽  
Tract Infections

Background: COVID-19 outbreak lead to nationwide lockdown on the March 16th, 2020 in Turkey. We aimed to quantitively determine the change in frequency of upper and lower respiratory tract infections and asthma in pediatric population associated with COVID-19. Methods: The electronic medical record data of pediatric population admitted to the emergency department (ED), outpatient and inpatient clinics and pediatric intensive care unit (PICU) were analyzed with the diagnosis of Influenza, upper and lower respiratory tract infections (URTI, LRTI) acute bronchiolitis and asthma. The data of the first year of the pandemic was compared with the previous year. Results: In total 112496 admissions were made between April 1, 2019 and March 31, 2021 in our hospital. A decline was observed in ED admissions (-73%) and outpatient clinic (-70%) visits, hospitalizations (-41.5%) and PICU admissions (-42%). The admissions with the diagnosis of Influenza and URTI had a decline from 4.26% to 0.37% (p=0.0001), and from 81.54% to 75.62% (p=0.0001), respectively. An increase was observed in the LRTI, acute bronchiolitis and asthma (from 8.22% to 10.01% (p=0.0001), from 2.76% to 3.07% (p=0.027) and from 5.96% to 14% (p=0.0001), respectively). Conclusions: A dramatic decrease was observed in the number of admissions to ED and inpatient clinics and outpatient clinic visits and PICU admissions, and, when the rates of admissions were compared, the general rate of admissions to ED showed a decrease while inpatient, outpatient clinics and PICU admissions demonstrated an increase during the pandemic.

scholarly journals A Three Point Assessment Protocol for Tympanoplasty Outcomes: A Retrospective Analysis

2020 ◽  
Vol 24 (04) ◽  
pp. e438-e443
Author(s):  
P. Naina ◽  
Apar Pokharel ◽  
Kamran Asif Syed ◽  
Mary John ◽  
Ajoy Mathew Varghese ◽  
...  
Keyword(s):  
Retrospective Analysis ◽  
Otitis Media ◽  
Surgical Outcome ◽  
Pediatric Population ◽  
Chronic Otitis Media ◽  
Tympanic Membrane Perforation ◽  
Factors Affecting ◽  
Assessment Protocol ◽  
Membrane Perforation ◽  
The Status

Abstract Introduction The surgical outcome of chronic otitis media (COM) of the mucosal type in the pediatric population with high rates of recurrent tympanic membrane perforation is indeed a concern for the attending surgeon. Objective The present study was done to evaluate the outcome of tympanoplasty in children with chronic otitis media mucosal type. Methods A retrospective analysis of the medical records of all children, aged < 16 years old, who underwent tympanoplasty for COM of the mucosal type was performed. These patients were addressed by a three-point assessment, for predicting outcome of tympanoplasty, which included the age of the patient, addressing the nasal/pharyngeal issues, and the status of the COM (discharging or dry). Surgical success was assessed in terms of graft uptake and improvement of hearing. Factors affecting the surgical outcome were also analyzed. Results A total of 90 children underwent type 1 tympanoplasty; 7 were lost to follow-up and 10 had incomplete audiometric results. In the 73 tympanoplasties analyzed, graft uptake was seen in 91.7% of the patients. Children with longer duration of ear discharge (> 8 years) had greater hearing loss. Children aged > 8 years old showed statistically significant higher chance of graft uptake (p = 0.021). Five of the six children who had graft rejection had bilateral disease. Conclusion A three-point assessment in the management of pediatric COM of the mucosal type offers good outcomes with post-tympanoplasty graft uptake rates > 90%.

scholarly journals Hepatocellular Carcinoma in the Pediatric Population: A Population Based Clinical Outcomes Study Involving 257 Patients from the Surveillance, Epidemiology, and End Result (SEER) Database (1973–2011)

HPB Surgery ◽  
2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Christine S. M. Lau ◽  
Krishnaraj Mahendraraj ◽  
Ronald S. Chamberlain
Keyword(s):  
Hepatocellular Carcinoma ◽  
Clinical Outcomes ◽  
Pediatric Population ◽  
Population Based ◽  
Seer Database ◽  
Distant Disease ◽  
Pediatric Malignancy ◽  
Advanced Tumor ◽  
Outcomes Study ◽  
Overall Mortality

Introduction. Hepatocellular carcinoma (HCC) is a rare pediatric cancer accounting for 0.5% of all pediatric malignancies. This study examines a large cohort of HCC patients in an effort to define the factors impacting clinical outcomes in pediatric HCC patients compared to adults. Methods. Demographic and clinical data on 63,771 HCC patients (257 pediatric patients ≤ 19 and 63,514 adult patients age ≥ 20) were abstracted from the SEER database (1973–2011). Results. HCC was more common among males (59.5% pediatric and 75.1% adults) and Caucasians (50.4% and 50.5%), p<0.05. Children more often presented with fibrolamellar variant HCC (24.1% versus 0.3%, p=0.71) and advanced HCC, including distant disease (33.1% versus 20.8%, p<0.001), and tumors > 4 cm in size (79.6% versus 62.0%, p=0.02). Pediatric HCC patients undergoing surgery (13.107 versus 8.324 years, p<0.001) had longer survival than adult HCC patients. Overall mortality was lower (65.8% versus 82.0%, p<0.001) in the pediatric HCC group. Conclusion. HCC is a rare pediatric malignancy that presents most often as an advanced tumor, >4 cm in Caucasian males. Children with HCC achieve significantly longer mean overall survival compared to adults with HCC, primarily attributable to the more favorable fibrolamellar histologic variant, and more aggressive surgical intervention, which significantly improves survival.

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