Reference intervals of serum folate and vitamin B12 developed from data of healthy subjects

2000 ◽  
Vol 5 (9) ◽  
pp. 383-387 ◽  
Author(s):  
Tijen Tanyalcin ◽  
Diler Aslan ◽  
Yusuf Kurtulmus ◽  
Nalan Gökalp ◽  
Kamil Kumanlioğlu
Keyword(s):  
Vitamin B12 ◽  
Healthy Subjects ◽  
Reference Intervals ◽  
Serum Folate ◽  
Folate And Vitamin B12

VITAMIN B12 AND FOLIC ACID VALUES IN PREMATURE INFANTS

PEDIATRICS ◽  
1972 ◽  
Vol 50 (4) ◽  
pp. 584-589
Author(s):  
Ambadas Pathak ◽  
Herman A. Godwin ◽  
Luis M. Prudent
Keyword(s):  
Folic Acid ◽  
Vitamin B12 ◽  
Premature Infants ◽  
Serum Vitamin ◽  
Serum Folate ◽  
Born Infant ◽  
Low Concentrations ◽  
Folate And Vitamin B12 ◽  
Relationship Of ◽  
The Relationship

The relationship of serum vitamin B12 and folic acid was studied in 24 premature infants. In 14 of the 24, low serum vitamin B12 values were found around 40 days of age. Serum folic acid concentrations were less frequently depressed and were usually associated with normal red cell folate values. No correlation between hematocrits and vitamin B12 or folate levels was found. It is suggested that low concentrations of serum folate and vitamin B12 result from low dietary intake coupled with increased demand by the prematurely born infant.

scholarly journals Plasma Total Homocysteine, Folate, and Vitamin B12 Status and Hospitalizations for Cardiovascular Disease

Pteridines ◽  
2007 ◽  
Vol 18 (1) ◽  
pp. 122-127
Author(s):  
Bakhouche Houcher ◽  
Mirande Candito ◽  
Pierre Gibelin
Keyword(s):  
Vitamin B12 ◽  
Serum Vitamin ◽  
Inverse Correlation ◽  
Serum Folate ◽  
Plasma Thcy ◽  
Total Homocysteine ◽  
Group 2 ◽  
Folate And Vitamin B12 ◽  
Plasma Total Homocysteine ◽  
Group 1

Abstract Elevated plasma total homocysteine (tHcy) is an independent risk factor for cardiovascular disease (CVD). Also known is that plasma folate and vitamin B12 influence homocysteine metabolism as cosubstrate and cofactor, respectively. This population-based study was conducted to evaluate the plasma concentrations of tHcy, folate, and vitamin B12 in 54 older patients aged ≥51 years (40 males; 14 females) of Nice hospital cardiology service. After excluding cases with a serum creatinine >120 mmol/L, we established the test properties of a plasma tHcy concentration <15 μmol/L (Group 1) or ≥15 μmol/L (Group 2). In the population aged ≥51 years, plasma tHcy was higher in women (18.0 μmol/L) than in men (15.5 μmol/L; not significant), conversely, serum vitamin B12 was higher in men (376.9 pg/ml) than in women (340.7 pg/ml; not significant). Average plasma tHcy was 11.5 μmol/L in Group 1 and 21.6 μmol/L in Group 2. Vice versa, serum vitamin B12 was higher in Group 1 (419.5 pg/ml) than in Group 2 (307.2 pg/ml) (p <0.05). Correlation analysis (Pearson's r) in the total study population (20-84 years) indicated an inverse correlation between serum folate and age (r = -0.231, p <0.05). In the subjects, aged ≥51 years, there was a significant negative correlation between age and tHcy levels (r = -0.283, p <0.05) and serum vitamin B12 concentrations (r = -0.326, p <0.01) but not with serum folate. However, in subjects with tHcy <15 μmol/L, a significant inverse correlation existed between plasma tHcy and serum folate (r = -0.455; p <0.05). In conclusion, these results highlight the relevance of the vitamin status and particularly of folate levels in the modulation of fasting tHcy levels in the patients with clinical hyperhomocysteinemia, defined as plasma tHcy >15 μmol/L.

Association of serum folate and vitamin B12 with pre-neoplastic cervical lesions

2020 ◽  
Vol 38 ◽  
pp. 223-228
Author(s):  
Nayara Nascimento Toledo Silva ◽  
Ana Carolina Silva Santos ◽  
Cláudia Martins Carneiro ◽  
Angélica Alves Lima
Keyword(s):  
Vitamin B12 ◽  
Serum Folate ◽  
Cervical Lesions ◽  
Folate And Vitamin B12

Serum Folate and Vitamin B12 Levels in Children from Mozambique

2004 ◽  
Vol 23 (8-9) ◽  
pp. 1301-1303 ◽  
Author(s):  
R. Leoncini ◽  
D. Vannoni ◽  
R. Guerranti ◽  
G. Cinci ◽  
A. Tabucchi ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Serum Folate ◽  
Folate And Vitamin B12

scholarly journals Validation of a Semi-Quantitative Food-Frequency Questionnaire for Dutch Pregnant Women from the General Population Using the Method or Triads

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1341 ◽  
Author(s):  
Trudy Voortman ◽  
Régine P.M. Steegers-Theunissen ◽  
Nienke E. Bergen ◽  
Vincent W. V. Jaddoe ◽  
Caspar W. N. Looman ◽  
...  
Keyword(s):  
Fatty Acids ◽  
General Population ◽  
Blood Cell ◽  
Vitamin B12 ◽  
Pregnant Women ◽  
Red Blood Cell ◽  
Food Frequency Questionnaire ◽  
Serum Folate ◽  
Food Frequency ◽  
Folate And Vitamin B12

Objective: We aimed to validate a food-frequency questionnaire (FFQ) for Dutch pregnant women, against three 24 h-recalls and blood concentrations of B-vitamins and fatty acids, using the method of triads. Methods: We included 83 pregnant women from the general population of Rotterdam, the Netherlands, at a median gestational age of 15.6 weeks. Participants completed three non-consecutive 24 h-recalls, and subsequently filled out the 293-item FFQ. Participants provided blood samples from which we analyzed serum folate and vitamin B12, as well as red blood cell folate, linoleic acid, and total saturated, monounsaturated, and polyunsaturated fatty acids. Results: Estimated energy intake did not differ between the FFQ and 24 h-recalls. Deattenuated Pearson’s correlation coefficients, between energy-adjusted nutrient intake estimates from the FFQ and the 24 h-recalls, ranged from 0.41 (fat) to 0.88 (fiber) for macronutrients, and were around 0.6 for most micronutrients, except for vitamin E (0.27). Using the triad method, we obtained validity coefficients of 0.86 (95% Confidence Interval (CI) 0.36, 1.00) for serum folate, 0.86 (95% CI 0.18, 1.00) for red blood cell folate, and 1.00 (95% CI 0.42, 1.00) for vitamin B12. Validity coefficients for serum fatty acids ranged from 0.22 to 0.67. Conclusion: This FFQ is a reliable tool for estimating intake of energy, macronutrients, folate and vitamin B12 among women in mid-pregnancy.

scholarly journals Effects of antiepileptic drugs on the serum folate and vitamin B12 in various epileptic patients

2016 ◽  
Vol 5 (4) ◽  
pp. 413-416 ◽  
Author(s):  
Hong-Li Huang ◽  
Hao Zhou ◽  
Nuan Wang ◽  
Chun-Yu Yu
Keyword(s):  
Vitamin B12 ◽  
Antiepileptic Drugs ◽  
Serum Folate ◽  
Epileptic Patients ◽  
Folate And Vitamin B12
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