The role of the mother–child relationship for anxiety disorders and depression: results from a prospective-longitudinal study in adolescents and their mothers

2014 ◽  
Vol 24 (4) ◽  
pp. 451-461 ◽  
Author(s):  
Eva Asselmann ◽  
Hans-Ulrich Wittchen ◽  
Roselind Lieb ◽  
Katja Beesdo-Baum
Keyword(s):  
Longitudinal Study ◽  
Anxiety Disorders ◽  
Prospective Longitudinal Study ◽  
Child Relationship ◽  
Mother Child Relationship ◽  
Prospective Longitudinal

Maternal anxiety disorders prior to conception, psychopathology during pregnancy and early infants’ development: a prospective-longitudinal study

2013 ◽  
Vol 16 (6) ◽  
pp. 549-560 ◽  
Author(s):  
Julia Martini ◽  
Julia Wittich ◽  
Johanna Petzoldt ◽  
Susanne Winkel ◽  
Franziska Einsle ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Anxiety Disorders ◽  
Maternal Anxiety ◽  
Prospective Longitudinal Study ◽  
Prospective Longitudinal

scholarly journals The Association of Serum Levels of Brain-Derived Neurotrophic Factor with the Occurrence of and Recovery from Delirium in Older Medical Inpatients

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
John Williams ◽  
Karen Finn ◽  
Vincent Melvin ◽  
David Meagher ◽  
Geraldine McCarthy ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Generalized Estimating Equations ◽  
Serum Levels ◽  
Apache Ii ◽  
Elisa Method ◽  
Prospective Longitudinal Study ◽  
Medical Inpatients ◽  
Prospective Longitudinal ◽  
The Relationship

Limited studies of the association between BDNF levels and delirium have given inconclusive results. This prospective, longitudinal study examined the relationship between BDNF levels and the occurrence of and recovery from delirium. Participants were assessed twice weekly using MoCA, DRS-R98, and APACHE II scales. BDNF levels were estimated using an ELISA method. Delirium was defined with DRS-R98 (score > 16) and recovery from delirium as ≥2 consecutive assessments without delirium prior to discharge. We identified no difference in BDNF levels between those with and without delirium. Excluding those who never developed delirium (n=140), we examined the association of BDNF levels and other variables with delirium recovery. Of 58 who experienced delirium, 39 remained delirious while 19 recovered. Using Generalized Estimating Equations models we found that BDNF levels (Wald χ2=7.155; df: 1, p=0.007) and MoCA (Wald χ2=4.933; df: 1, p=0.026) were associated with recovery. No significant association was found for APACHE II, dementia, age, or gender. BDNF levels do not appear to be directly linked to the occurrence of delirium but recovery was less likely in those with continuously lower levels. No previous study has investigated the role of BDNF in delirium recovery and these findings warrant replication in other populations.

scholarly journals Changes in psychopathological symptoms during pregnancy and after delivery: A prospective-longitudinal study in women with and without anxiety and depressive disorders prior to pregnancy

2021 ◽  
Author(s):  
Eva Asselmann ◽  
Stefanie Kunas ◽  
Hans-Ulrich Wittchen ◽  
Julia Martini
Keyword(s):  
Anxiety Disorders ◽  
Early Pregnancy ◽  
Depressive Disorders ◽  
Paranoid Ideation ◽  
Prospective Longitudinal Study ◽  
Psychopathological Symptoms ◽  
Phobic Anxiety ◽  
Symptom Changes ◽  
Prospective Longitudinal

Background: The role of anxiety and depressive disorders prior to pregnancy for changes in peripartum psychopathological symptoms has not been resolved yet. Methods: A regional-epidemiological sample of 306 women was prospectively followed up in seven waves from early pregnancy until 16 months postpartum. Lifetime DSM-IV anxiety and depressive disorders were assessed at baseline with the CIDI-V. Psychopathological symptoms (somatization, obsession–compulsion, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation, and psychoticism) were measured with the BSI three times during pregnancy and three times after delivery. Results: Multilevel analyses revealed that women with versus without lifetime anxiety (β=0.22 to β=0.32) and depressive (β=0.24 to β=0.34) disorders prior to pregnancy experienced higher peripartum psychopathological symptoms. All symptoms linearly decreased during pregnancy (β=-0.02 to β=-0.07 per month). Somatization (β=-0.46) was lower, whereas paranoid ideation (β=0.26) and obsession-compulsion (β=0.21) were higher after delivery than during pregnancy. Though, obsession-compulsion linearly decreased after delivery (β=-0.02). Lifetime anxiety disorders prior to pregnancy interacted with linear changes in anxiety (β=-0.04) and phobic anxiety (β=-0.05) during pregnancy. That is, only women with but not without anxiety disorders prior to pregnancy experienced a linear decline in anxiety and phobic anxiety during pregnancy. Limitations: Lifetime anxiety and depressive disorders were assessed in early pregnancy and might be biased. Conclusions: Peripartum psychopathological symptoms are higher in women with versus without lifetime anxiety and depressive disorders prior to pregnancy, but symptom changes only slightly vary by lifetime diagnostic status.

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