Onychomycosis: Quality of Studies

2003 ◽  
Vol 7 (4) ◽  
pp. 312-316 ◽  
Author(s):  
Aditya K. Gupta ◽  
Jennifer E. Ryder ◽  
Robyn Bluhm ◽  
Andrew Johnson ◽  
Richard C. Summerbell

Objective: The quality of original clinical trial publications pertaining to the use of oral antifungal agents to treat onychomycosis was evaluated using predetermined criteria. Methods: The list of studies included in this analysis was determined by conducting a search in Medline. For each clinical trial, two independent reviewers each determined a composite score by evaluating a list of criteria that were felt to represent a good study, for example, randomization and blinding, prior sample size calculated, and treatment regimen clearly explained. A citation count was performed to determine whether higher-quality papers were cited more often than lower-quality papers. Results: Forty-five studies were included in this quality analysis of study design. Of these, 27 were considered to be “high quality” (score greater than or equal to 11 out of 20). A significant correlation coefficient of 0.997 was found between the two reviewers ( P < 0.00001). Higher-quality papers were cited significantly more often than lower-quality papers ( P = 0.03). Conclusion: The scale that we use to evaluate the quality of onychomycosis studies has high interrater reliability. According to this scale, many published studies (18 out of 45) pertaining to treatments for onychomycosis do not meet the criteria required to be considered “high quality.”

Lontara ◽  
2021 ◽  
Vol 2 (2) ◽  
pp. 57-68
Author(s):  
Nurbeti Salam ◽  
Bambang Ariyanto ◽  
Maharani Gayatri

Services in the field of radiology which are health support services also need to maintain and improve the quality of their services. Radiology is one of the supporting units of health services in establishing the diagnosis of a disease and also needs to maintain and improve the quality of services appropriately and safely, both for patients (users), radiographers (officers) and the community or the surrounding environment. This study aims to determine the quality of radiology services at the Center for Community Lung Health (BBKPM) Makassar. The method used is descriptive research with a quantitative approach. The population is all patients in the radiology installation of the Center for Community Lung Health (BBKPM) with a sample of 158 people. The results showed that the quality of radiology services in terms of timeliness was categorized as very high, namely 91.86%. The cost of Thorax photo examination services is relatively cheap and affordable and the service waiting time reaches a fairly high-quality value of 86.79%. The information aspect reached a high-quality value, namely 85.97%. The technical executor of the Thorax photo examination is carried out by a radiographer and the executor of the diagnostic results is a radiologist (radiology specialist) who has achieved a fairly high-quality score of 97.15%. Aspects of Human Relations have reached a fairly high-quality score of 87.00%. Environmental Aspects achieved a quality value of 97.57%. It is recommended that the Makassar BBKPM management provide a complaint box (suggestion box) in the radiology room to evaluate services.


2021 ◽  
Vol 24 (1) ◽  
pp. 15-24
Author(s):  
Isik Sezen ◽  
◽  
Elif Akpinar Kulekci ◽  
Erdem Karadag

The study aimed to analyze the visual quality of the Educational Institutions and their Surroundings (EITS) in the campus of Ataturk University in Erzurum city of Turkey. Visual Quality Analysis Questionnaire was applied to 74 students studying at the Faculty of Architecture and Design. The questionnaire consisted of 21 EITS. Results were analyzed using Variance and Duncan multiple comparison. It was determined that Faculty of Fishery (EITS13) had the highest visual quality score (3.243), followed by Agriculture Faculty (EITS1: 3.134) and the Divine Faculty (EITS2: 2.906). The Faculty of Veterinary Medicine had the lowest visual quality score (EITS11: 2.165), followed by High-Tech Research Centre (EITS20: 2.243) and Faculty of Law (EITS16: 2.315). Statistically significant relationship was found between the department of the students and the scores they gave to Sports Science Faculty (EITS1), Education Faculty (EITS4), Faculty of Medicine (EITS10), Faculty of Veterinary Medicine (EITS11), Faculty of Fine Arts and Tourism (EITS15), and Rectorate Building (EITS19). Among the Visual Quality Criteria (VQC) of EITS, accessibility to the structure (VQC12) was the most effective criterion (2.927, p<0.05). This study recommended the correction of design deficiencies to compensate for the lack of visual quality of new buildings or to improve the entire landscape of the campus.


2018 ◽  
Vol 64 ◽  
Author(s):  
N.V. Bespalova ◽  
M.M. Gomola ◽  
T.I. Yakovleva

The article is devoted to the urgent theoretical and practical problems of the quality control of the chocolate confectionery products in cafes and restaurants. The authors analyze the modern approaches to the quality control of the chocolate confectionery products. The practical recommendations can be useful for the process of selection of the high quality raw materials. The criteria for the quality control of the chocolate confectionery products have been given. Some ways to improve the quality of he chocolate confectionery products have been discussed.


2013 ◽  
Vol 2013 ◽  
pp. 1-13
Author(s):  
Li-Min Liu

Clinical trials are crucial to modern healthcare industries, and information technologies have been employed to improve the quality of data collected in trials and reduce the overall cost of data processing. While developing software for clinical trials, one needs to take into account the similar patterns shared by all clinical trial software. Such patterns exist because of the unique properties of clinical trials and the rigorous regulations imposed by the government for the reasons of subject safety. Among the existing software development methodologies, none, unfortunately, was built specifically upon these properties and patterns and therefore works sufficiently well. In this paper, the process of clinical trials is reviewed, and the unique properties of clinical trial system development are explained thoroughly. Based on the properties, a new software development methodology is then proposed specifically for developing electronic clinical trial systems. A case study shows that, by adopting the proposed methodology, high-quality software products can be delivered on schedule within budget. With such high-quality software, data collection, management, and analysis can be more efficient, accurate, and inexpensive, which in turn will improve the overall quality of clinical trials.


2020 ◽  
Author(s):  
Shichong Liao ◽  
Liao Shichong ◽  
Chen Xinyue ◽  
Tu Yi ◽  
Sun Shengrong ◽  
...  

Abstract Background: To evaluate the quality, reliability, comprehensiveness and accuracy of the popular science information related to the Corona Virus Disease 2019 (COVID-19) on the Chinese website.Methods: Searching for scientific articles with the keywords of "novel coronavirus pneumonia" in Baidu, Sogou and 360 search engine at 14:00 on May 22, 2020, and collecting information such as article source, length, upload time, etc. Using JAMA score and 5-point DISCERN scale, two specialists independently analyzed the reliability and quality of scientific articles. Combined with the "Novel Coronavirus Pneumonia Diagnosis and Treatment Program (Trial Version 6)", we made corresponding evaluation on the comprehensiveness and accuracy of articles. Results: A total of 45 scientific articles were included in the study. The average number of words is 2692.27±1267.61, and the average upload time is 11.8±10.80 days. Those popular scientific articles are mainly uploaded by government agencies and individuals. However, the JAMA score, DISCERN score, content comprehensiveness and accuracy of the articles were generally low. Among the 45 popular scientific articles, 27 articles were classified as accurate-content group and 18 articles were classified as misleading-content group. Scientific articles of accurate-content groups mainly came from government agencies, universities and hospitals. The publication date of articles in the accurate-content group is closer, the scores of JAMA, DISCERN and content comprehensiveness were higher (P<0.05). The results also showed that JAMA score, DISCERN score, content comprehensiveness and accuracy of popular science articles uploaded by government agencies, universities and hospitals were higher (P<0.05). The results indicated that there was a significant positive correlation between the scores of JAMA, DISCERN, comprehensiveness and accuracy (P<0.05). Conclusion: Although there are many scientific articles related to the novel coronavirus pneumonia on the Chinese website, the overall detection rate of high-quality scientific articles were low. We are Looking forward to more high-quality medical scientific articles published by government agencies, universities and hospitals. It is suggested that search engines adopt a more optimized sorting method to help more readers get high-quality information.


2013 ◽  
Vol 95 (5) ◽  
pp. 341-344 ◽  
Author(s):  
TM Yeung ◽  
ND D’Souza

Introduction Haemorrhoids are the most common benign condition seen by colorectal surgeons. At clinic appointments, advice given about lifestyle modification or surgical interventions may not be understood fully by patients. Patients may use the internet for further research into their condition. However, the quality of such information has not been investigated before. This study assessed the quality of patient information on surgical treatment of haemorrhoids on the internet. Methods Four searches were carried out using the search terms ‘surgery for haemorrhoids’ and ‘surgery for piles’ on two search engines (Google and Yahoo). The first 50 results for each search were assessed. Sites were evaluated using the DISCERN instrument. Results In total, 200 websites were assessed, of which 144 fulfilled the inclusion criteria. Of these, 63 (44%) were sponsored by herbal remedies for haemorrhoids. Eighty-nine (62%) mentioned conservative treatment options but eleven (8%) did not include surgery in their treatment options. Only 38 sites (27%) mentioned recurrence of haemorrhoids following surgery and 28 sites (20%) did not list any complications. Overall, 19 websites (14%) were judged as being of high quality, 66 (45%) as moderate quality and 58 (40%) as low quality. Conclusions The quality of information on the internet is highly variable and a significant proportion of websites assessed are poor. The majority of websites are sponsored by private companies selling alternative treatments for haemorrhoids. Clinicians should be prepared to advise their patients which websites can provide high-quality information on the surgical treatment of haemorrhoids.


2018 ◽  
Vol 30 (1) ◽  
pp. 13-22 ◽  
Author(s):  
Markos Kyriakos Tomidis Chatzimanouil ◽  
Louise Wilkens ◽  
Hans-Joachim Anders

BackgroundIn 2004, researchers reported that the number of nephrology clinical trials was low and that the reporting quality of such trials was suboptimal. Furthermore, the number or quality of preclinical kidney-related studies has not been systematically evaluated.MethodsWe performed a systematic review of randomized clinical trials published in 1966–2017 (listed in the Cochrane Library) and preclinical studies published in 1945–2017 (listed in PubMed). For reporting quality analysis, we evaluated the final main paper of 118 clinical trial reports and 135 preclinical studies published in leading journals in 1996, 2006, and 2016 on the basis of criteria from the widely used CONSORT and ARRIVE guidelines.ResultsThe annual number of reports of clinical kidney-related trials more than doubled between 2004 and 2014 along with reports in other medical disciplines. Hypertension remains the dominant focus of study, but ongoing trials also center on CKD, ESRD, and AKI. The reporting quality analysis revealed improvements, but deficits in reporting of clinical trial design, mode of randomization, and intention-to-treat analysis remain. Annual numbers of kidney-related preclinical studies remained low between 1945 and 2017 compared with other disciplines. Reporting quality analysis of preclinical studies revealed substantial reporting deficits across all leading journals, with little improvement over the last 20 years, especially for group size calculations, defining primary versus secondary outcomes, and blinded analysis.ConclusionsNephrology studies keep increasing in number but still lag behind other medical disciplines, and the quality of data reporting in kidney research can be further improved.


PLoS ONE ◽  
2018 ◽  
Vol 13 (4) ◽  
pp. e0195068 ◽  
Author(s):  
Juan Pasquau ◽  
Carmen Hidalgo-Tenorio ◽  
María Luisa Montes ◽  
Alberto Romero-Palacios ◽  
Jorge Vergas ◽  
...  

1994 ◽  
Vol 13 (7) ◽  
pp. 481-492 ◽  
Author(s):  
Klaus Linde ◽  
Wayne B. Jonas ◽  
Dieter Melchart ◽  
Felege Worku ◽  
Hildebert Wagner ◽  
...  

1 We conducted an overview and quantitative meta-analysis of all experimental literature on the protective effects of serial agitated dilutions (SADs) of toxin preparations. 2 Articles were systematically collected and evaluated for scientific quality using pre-defined methodological criteria and then independently analysed for validity. 3 We found 105 publications exploring the effects of SAD preparations in toxicological systems. 4 The quality of evidence in these studies was low with only 43% achieving one half of the maximum possible quality score and only 31 % reported in a fashion that permitted reevaluation of the data. 5 Very few studies were independently replicated using comparable models. 6 Among the high quality studies, positive effects were reported 50% more often than negative effects. 7 Four of 5 outcomes meeting quality and comparability criteria for meta-analysis showed positive effects from SAD preparations. 8 Average percent protection over controls in these preparations was 19.7 (95%Cl 6.2-33.2). 9 Further research with special attention to methodological detail and independent replicafion should be done.


Author(s):  
A. T. Kunakbaeva ◽  
A. M. Stolyarov ◽  
M. V. Potapova

Free-cutting steel gains specific working properties thanks to the high content of sulfur and phosphorus. These elements, especially sulfur, have a rather high tendency to segregation. Therefore, segregation defects in free-cutting steel continuously cast billets can be significantly developed. The aim of the work was to study the influence of the chemical composition of freecutting steel and casting technological parameters on the quality of the macrostructure of continuously cast billets. A metallographic assessment of the internal structure of cast metal made of free-cutting steel and data processing by application of correlation and regression analysis were the research methods. The array of production data of 43 heats of free-cutting steel of grade A12 was studied. Steel casting on a five-strand radial type continuous casting machine was carried out by various methods of metal pouring from tundish into the molds. Metal of 19 heats was poured with an open stream, and 24 heats – by a closed stream through submerged nozzles with a vertical hole. High-quality billets had a cross-sectional size of 150×150 mm. The macrostructure of high-quality square billets made of free-cutting steel of A12 grade is characterized by the presence of central porosity, axial segregation and peripheral point contamination, the degree of development of which was in the range from 1.5 to 2.0 points, segregation cracks and strips – about 1.0 points. In the course of casting with an open stream, almost all of these defects are more developed comparing with the casting by a closed stream. As a result of correlation and regression analysis, linear dependences of the development degree of segregation cracks and strips both axial and angular on the sulfur content in steel and on the ratio of manganese content to sulfur content were established. The degree of these defects development increases with growing of sulfur content in steel of A12 grade. These defects had especially strong development when sulfur content in steel was of more than 0.10%. To improve the quality of cast metal, it is necessary to have the ratio of the manganese content to the sulfur content in the metal more than eight.


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