Conservation areas are originally well-known for protecting landscape features and wildlife. They are playing key role in conserving and providing a wide range of ecosystem services, social, economic and cultural benefits as well as vital places for climate mitigation and adaptation. We have analyzed decadal changes in land cover and status of vegetation cover in the conservation area using both national level available data on land use land cover (LULC) changes (1990-2010) and normalized difference vegetation index (NDVI) (2010-2018) in Annapurna conservation area. LULC showed the barren land as the most dominant land cover types in all three different time series 1990, 2000 and 2010 with followed by snow cover, grassland, forest, agriculture and water body. The highest NDVI values were observed at Southern, Southwestern and Southeastern part of conservation area consisting of forest area, shrub land and grassland while toward low to negative in the upper middle to the Northern part of the conservation area.