The purpose of this study was to evaluate the four-dimensional relationship between land use, accessibility, density, and surface runoff in urban areas. In contemporary literature, a series of studies have been conducted that extensively discuss the natural components associated with the surface runoff in urban areas. However, the dynamic and complex dimensions of the urban form, such as land use, accessibility, and density, are yet to be fully understood. In this study, a 4D diagram was utilized to identify relationships between dimensions, in addition to decision tree analysis, to explore the structural flow between selected variables. Furthermore, a structural equation modeling (SEM) approach was employed with the purpose of investigating the direct, indirect, and moderating effects on the targeted dependent variable, surface runoff. The results of the analysis reported a strong correlation between land use, accessibility, density, and surface runoff, with an R-squared value of 0.802, which indicates an acceptable model accuracy by the international standard. A positive relationship between the four dimensions was indicated by the higher accessibility; the higher density in terms of a higher floor space index (FSI), ground space index (GSI), and open space; the building height of the adjacent buildings; the higher diversity of the land use; and the higher surface runoff. Accordingly, the findings of the study offer policy implications in the fields of land use planning, zoning regulations and overall urban development planning towards achieving climate resilient cities.