Increased Concentrations of Atherogenic Proteins in Aneurysm Sac Are Associated with Wall Enhancement of Unruptured Intracranial Aneurysm

2022 ◽  
Author(s):  
Daizo Ishii ◽  
Alexander Choi ◽  
Anthony Piscopo ◽  
Zain Mehdi ◽  
Ashrita Raghuram ◽  
...  
Keyword(s):  
Intracranial Aneurysm ◽  
Unruptured Intracranial Aneurysm

Abstract TP295: Stroke Prevention Surgery > Quality of Life and Cognitive Ability to Drive Are Maintained After Surgical Repair of Unruptured Intracranial Aneurysm

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Joan M ODonnell ◽  
Maurizio Manuguerra ◽  
Jemma L Hodge ◽  
Greg Savage ◽  
Michael K Morgan
Keyword(s):  
Quality Of Life ◽  
Intracranial Aneurysm ◽  
Surgical Management ◽  
Cognitive Abilities ◽  
Short Form ◽  
Unruptured Intracranial Aneurysm ◽  
Significant Difference ◽  
Ability To Drive

Background: Studies have questioned the effectiveness of surgery for the management of unruptured intracranial aneurysm (uIA). Few studies have examined the ability to drive and quality of life (QOL) after surgery for uIA. Objective: This study examined the effectiveness of surgical management of uIA by measuring patients’ perceived quality of life and their cognitive abilities related to driving. Methods: Between January 2011 and January 2016 patients with a uIA were assessed using the Quality Metric Short Form 36 (SF36) and the off-road driver screening instrument DriveSafeDriveAware. Reassessments were conducted at the 6-week post-operative follow-up for surgical patients and at 12-month follow-up for surgical and conservatively managed patients. Results: 175 patients enrolled in the study, of which 112(66%) had surgical management of their aneurysm. For the surgical cases who completed all assessments (N=74), there was a trend for the DriveSafe pre-operative mean score of 108 (SD 10.7) to be lower than the 6-week and 12-month post-operative mean scores (111 SD 9.7 and 112 SD 10.2 respectively)(p=0.05). There were no significant changes in DriveAware scores at any epoch or between patient groups nor in the MCS in the surgical group.. There was a significant decline in PCS scores at 6 weeks post-operatively which recovered at 12 months (52 SD 8.1, 46 SD 6.8 and 52 SD 7.1 respectively)( p <0.01). There was no significant difference in 12-month mRS scores between the surgical cases who completed with cases who did not complete all assessments. Conclusion: Surgery for uIA did not affect cognitive abilities for driving at 6 weeks or 12 months after surgery. There was a decline in the QOL in the first months after surgery, however QOL returned to pre-surgical status 12 months after surgery. If the risk of seizures is low and there are no post-operative complications, returning to driving can be recommended.

scholarly journals 颅内未破裂动脉瘤的诊断治疗现状及研究进展

2019 ◽  
Vol 2 (2) ◽  
pp. 36
Author(s):  
国栋 张 ◽  
长武 窦
Keyword(s):  
Intracranial Aneurysm ◽  
Unruptured Intracranial Aneurysm

颅内未破裂动脉瘤(unruptured intracranial aneurysm, UIA)多指未发生破裂出血的颅内动脉瘤，多因其它疾病（如头痛头晕）或颅神经症状（视力下降、动眼神经麻痹）而行CTA或MRA检查时发现。对于颅内未破裂动脉瘤的治疗意见尚无统一标准。本文对颅内未破裂动脉瘤的诊断方法、治疗方法及患者的临床表现进行综述，以期为临床医生诊断、治疗颅内未破裂动脉瘤提供参考。

Is acute reperfusion therapy safe in acute ischemic stroke patients who harbor unruptured intracranial aneurysm?

2015 ◽  
Vol 10 (SA100) ◽  
pp. 113-118 ◽  
Author(s):  
Ashkan Mowla ◽  
Karanbir Singh ◽  
Sandhya Mehla ◽  
Mohammad K. Ahmed ◽  
Peyman Shirani ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Intracranial Aneurysm ◽  
Acute Ischemic Stroke ◽  
Reperfusion Therapy ◽  
Stroke Patients ◽  
Unruptured Intracranial Aneurysm

Abstract WP120: Readmission Trends Related to Unruptured Intracranial Aneurysm Treatment

Stroke ◽  
2019 ◽  
Vol 50 (Suppl_1) ◽  
Author(s):  
Tapan Mehta ◽  
Smit Patel ◽  
Shailesh Male ◽  
Andrew Zhang ◽  
Adam Khan ◽  
...  
Keyword(s):  
Intracranial Aneurysm ◽  
Unruptured Intracranial Aneurysm ◽  
Aneurysm Treatment
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