In vitro antioxidant activity and phenolic contents in methanol extracts from medicinal plants

2012 ◽  
Vol 22 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Sanjay Guleria ◽  
A. K. Tiku ◽  
Gurjinder Singh ◽  
Apurva Koul ◽  
Sahil Gupta ◽  
...  
2019 ◽  
Vol 48 (1) ◽  
pp. 125-131 ◽  
Author(s):  
M. Chaalal ◽  
S. Ouchemoukh ◽  
C. Mehenni ◽  
N. Salhi ◽  
O. Soufi ◽  
...  

2020 ◽  
Vol 11 (4) ◽  
pp. 6301-6306
Author(s):  
Akilandeswari G ◽  
Bupesh G ◽  
Vijaya Anand A ◽  
Saradhadevi K M ◽  
Mayur Mausoom Phukan ◽  
...  

Plants are adundantly and are very promisive to be used as source of drugs in many diseases or infections and also it is a main agents of antioxidants which prevents the oxidative stress that are caused by the free radicals. There are numerous studies based on the pharmaceutical and classification of medicinal plants throughout the world. Leaves, fruits, roots are most frequently plant parts used in many research and studies. Here the present study was aimed to evaluate the in vitro antioxidant activity of aqueous and ethanol leaf extracts of Andrographis paniculata Nees and Rhinacanthus nasutus Kurz. Antioxidant is a substance which is used to prevent some types of cell damage in the body. Determination of their in vitro antioxidant activity were carried out by using methods such as DPPH (2,2-diphenyl-1picrylhydrazyl assay), ABTS (2,2′-azinobis (3-ethylbenzothiazolin 6-sulfonic acid assay), FRAP (ferric reducing antioxidant power assay) and SOD (super oxide anion scavenging) assay, H2O2 (hydrogen peroxide radical scavenging) assay. Moreover the ethanolic leaf extracts showed best antioxidant activity than the aqueous leaf extracts. Experimental results reveals that the leaves of A. paniculata have potent antioxidant and free radical scavenging activity than R. nasutus. Further investigation must be done for these two medicinal plants for the discovery of the bioactive compounds.


2016 ◽  
Vol 10 (23) ◽  
pp. 501-507 ◽  
Author(s):  
Marius Lompo ◽  
Rakiatou Traor eacute ◽  
Noufou Ou eacute draogo ◽  
F eacute lix Kini ◽  
Andr eacute Tibiri ◽  
...  

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
B Svobodova ◽  
L Polesna ◽  
M Orsak ◽  
J Lachman ◽  
J Vadlejch ◽  
...  

2020 ◽  
Vol 11 (1) ◽  
pp. 806-812
Author(s):  
GopiKrishna Rakam ◽  
Raja Sundararajan

The purpose of the contemporary in vitro work implemented was to examine the antioxidant effect of Bougainvillea glabra and Mucuna pruriens methanol extracts. Methanol extracts of Bougainvillea glabra and Mucuna pruriens were screened individually for different in vitro antioxidant activity. Commercial antioxidants such as vitamin E, Ascorbic acid were used as reference standard. For ABTS+ assay IC50 value of Bougainvillea glabra & Mucuna pruriens metha­nol extract were found to be 17.1μg/ml and 23.2μg/ml correspondingly. Likewise, the IC50 values for xanthine oxidase inhibitory activity for Bougainvillea glabra and Mucuna pruriens was found to be 46.7μg/ml and 95.1μg/ml, respectively. For scavenging of various assay models like nitric oxide, hydroxyl and superoxide anion scavenging activity, the IC50 values for Bougainvillea glabra were found to be 45.3μg/ml, 70.1μg/ml and 38.1μg/ml respectively. The IC50 values for Mucuna pruriens for nitric oxide, hydroxyl and superoxide anion scavenging activity, were found to be 92.1μg/ml, 43.4μg/ml and 50.3μg/ml respectively. Bougainvillea glabra and Mucuna pruriens methanol extracts showed 50 % inhibition effect at concentrations 118 μg/ml and 121 μg/ml respectively for lipid peroxidation assay. The IC50 values for DPPH scavenging assay for Bougainvillea glabra and Mucuna pruriens was found to be 13.24μg/ml and 14.4μg/ml correspondingly. For DMPD assay Bougainvillea glabra and Mucuna pruriens possess the IC50 value 16.34 μg/ml and 17.4 μg/ml correspondingly. Methanol extracts of Bougainvillea glabra and Mucuna pruriens exhibited potent in vitro antioxidant activity.


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