Metal-free greener method for the synthesis of densely functionalized pyrroles via a one-pot three-component reaction

2018 ◽  
Vol 16 (1) ◽  
pp. 111-116 ◽  
Author(s):  
Maryam Fatahpour ◽  
Nourallah Hazeri ◽  
Malek Taher Maghsoodlou ◽  
Mojtaba Lashkari
Keyword(s):  
One Pot ◽  
Metal Free ◽  
Three Component Reaction

Three-component 3-(phosphoryl)methylindole synthesis from indoles, H-phosphine oxides and carbonyl compounds under metal-free conditions

2019 ◽  
Vol 21 (4) ◽  
pp. 792-797 ◽  
Author(s):  
Jiaoting Pan ◽  
Runmin Zhao ◽  
Jiami Guo ◽  
Dumei Ma ◽  
Ying Xia ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Indole Derivatives ◽  
Phosphine Oxides ◽  
One Pot ◽  
Metal Free ◽  
Three Component Reaction ◽  
Acid Catalyzed

The first facile and efficient acid-catalyzed three-component reaction of indoles, H-phosphine oxides and carbonyl compounds has been developed, providing a general, one-pot approach to structurally diverse C3-alkylated indole derivatives.

scholarly journals Pentafluoropropionic Acid: An Efficient and Metal-Free Catalyst for the One-Pot Synthesis of Tetrahydrobenzo[b]pyran Derivatives

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Naser Montazeri ◽  
Taghva Noghani ◽  
Mona Ghorchibeigy ◽  
Rozita Zoghi
Keyword(s):  
Reaction Time ◽  
Aromatic Aldehyde ◽  
One Pot ◽  
Short Reaction Time ◽  
Metal Free ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
The One ◽  
High Yields

Pentafluoropropionic acid (PFPA) efficiently catalyzes the one-pot, three-component reaction of aromatic aldehyde, malononitrile, and dimedone to yield tetrahydrobenzo[b]pyran derivatives in high yields. This method is of great value because of its easy processing, short reaction time, environmentally, and high yields.

One-Pot Regiospecific Synthesis of Imidazo[1,2-a]pyridines: A Novel, Metal-Free, Three-Component Reaction for the Formation of C–N, C–O, and C–S Bonds

2013 ◽  
Vol 16 (1) ◽  
pp. 146-149 ◽  
Author(s):  
Hua Cao ◽  
Xiaohang Liu ◽  
Limin Zhao ◽  
Jinghe Cen ◽  
Jingxin Lin ◽  
...  
Keyword(s):  
One Pot ◽  
Metal Free ◽  
Three Component Reaction

Metal-free synthesis of quinoline-2,4-dicarboxylate derivatives using aryl amines and acetylenedicarboxylates through pseudo three-component reaction

2021 ◽  
Author(s):  
Saghir Ali ◽  
Abu Taleb Khan
Keyword(s):  
Molecular Iodine ◽  
One Pot ◽  
Metal Free ◽  
Three Component Reaction ◽  
Aryl Amines

An efficient, useful and one-pot protocol for the synthesis of quinoline-2,4-dicarboxylate scaffolds is accomplished from aryl amines and dimethyl/diethyl acetylenedicarboxylates using 20 mol% molecular iodine as a catalyst in acetonitrile...

ChemInform Abstract: One-Pot Regiospecific Synthesis of Imidazo[1,2-a]pyridines: A Novel, Metal-Free, Three-Component Reaction for the Formation of C-N, C-O, and C-S Bonds.

ChemInform ◽  
2014 ◽  
Vol 45 (23) ◽  
pp. no-no
Author(s):  
Hua Cao ◽  
Xiaohang Liu ◽  
Limin Zhao ◽  
Jinghe Cen ◽  
Jingxin Lin ◽  
...  
Keyword(s):  
One Pot ◽  
Metal Free ◽  
Three Component Reaction

Microwave-assisted synthesis of novel 2,3-disubstituted imidazo[1,2-a]pyridines via one-pot three component reactions

RSC Advances ◽  
2015 ◽  
Vol 5 (25) ◽  
pp. 19724-19733 ◽  
Author(s):  
Shaik Karamthulla ◽  
Md. Nasim Khan ◽  
Lokman H. Choudhury
Keyword(s):  
Microwave Irradiation ◽  
Molecular Iodine ◽  
Microwave Assisted Synthesis ◽  
One Pot ◽  
Metal Free ◽  
Microwave Assisted ◽  
Three Component Reaction

An expeditious one-pot, metal-free, three-component reaction of arylglyoxals, cyclic 1,3-dicarbonyls and 2-aminopyridines in the presence of molecular iodine under microwave irradiation is reported.

One-Pot Regiospecific Synthesis of Indolizines: A Solvent-Free, Metal-Free, Three-Component Reaction of 2-(Pyridin-2-yl)acetates, Ynals, and Alcohols or Thiols

2018 ◽  
Vol 20 (8) ◽  
pp. 2477-2480 ◽  
Author(s):  
Daji Yang ◽  
Yue Yu ◽  
Yuanheng Wu ◽  
Huiyi Feng ◽  
Xuechen Li ◽  
...  
Keyword(s):  
Solvent Free ◽  
One Pot ◽  
Metal Free ◽  
Three Component Reaction ◽  
Free Metal

Synthesis of benzofuro[2,3-c]pyridines via a one-pot three-component reaction

2014 ◽  
Vol 12 (27) ◽  
pp. 4885-4889 ◽  
Author(s):  
Jiaxing Hu ◽  
Zhihong Deng ◽  
Xueqiong Zhang ◽  
Fanglin Zhang ◽  
Hua Zheng
Keyword(s):  
Synthetic Route ◽  
Reaction Conditions ◽  
One Pot ◽  
Metal Free ◽  
One Pot Synthesis ◽  
Three Component Reaction

A convenient one-pot synthesis of polysubstituted benzofuro[2,3-c]pyridines by three-component is developed. It provides a flexible and rapid synthetic route for the construction of benzofuro[2,3-c]pyridines under mild and metal-free reaction conditions in moderate to good yields (up to 83%).

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