Three-component 3-(phosphoryl)methylindole synthesis from indoles, H-phosphine oxides and carbonyl compounds under metal-free conditions

2019 ◽  
Vol 21 (4) ◽  
pp. 792-797 ◽  
Author(s):  
Jiaoting Pan ◽  
Runmin Zhao ◽  
Jiami Guo ◽  
Dumei Ma ◽  
Ying Xia ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Indole Derivatives ◽  
Phosphine Oxides ◽  
One Pot ◽  
Metal Free ◽  
Three Component Reaction ◽  
Acid Catalyzed

The first facile and efficient acid-catalyzed three-component reaction of indoles, H-phosphine oxides and carbonyl compounds has been developed, providing a general, one-pot approach to structurally diverse C3-alkylated indole derivatives.

scholarly journals Brønsted acid-catalyzed metal-free one-pot synthesis of benzimidazoles via [4+1] heteroannulation of ortho-phenylenediamines with β-oxodithioesters

ARKIVOC ◽  
2017 ◽  
Vol 2018 (2) ◽  
pp. 81-89
Author(s):  
Abhijeet Srivastava ◽  
Gaurav Shukla ◽  
Dhananjay Yadav ◽  
Maya Shankar Singh
Keyword(s):  
Bronsted Acid ◽  
Brønsted Acid ◽  
One Pot ◽  
Metal Free ◽  
One Pot Synthesis ◽  
Brönsted Acid ◽  
Acid Catalyzed

Metal-free greener method for the synthesis of densely functionalized pyrroles via a one-pot three-component reaction

2018 ◽  
Vol 16 (1) ◽  
pp. 111-116 ◽  
Author(s):  
Maryam Fatahpour ◽  
Nourallah Hazeri ◽  
Malek Taher Maghsoodlou ◽  
Mojtaba Lashkari
Keyword(s):  
One Pot ◽  
Metal Free ◽  
Three Component Reaction

ChemInform Abstract: Magnetically Separable Sulfonic Acid Catalyzed One-Pot Synthesis of Diverse Indole Derivatives.

ChemInform ◽  
2016 ◽  
Vol 47 (3) ◽  
Author(s):  
Jagatheeswaran Kothandapani ◽  
Asaithampi Ganesan ◽  
Subramaniapillai Selva Ganesan
Keyword(s):  
Sulfonic Acid ◽  
Indole Derivatives ◽  
One Pot ◽  
One Pot Synthesis ◽  
Acid Catalyzed ◽  
Magnetically Separable

Camphorsulfonic Acid Catalyzed One-Pot Three-Component Reaction for the Synthesis of Fused Quinoline and Benzoquinoline Derivatives

2017 ◽  
Vol 82 (23) ◽  
pp. 12416-12429 ◽  
Author(s):  
Radhakrishna Gattu ◽  
Prasanta Ray Bagdi ◽  
R. Sidick Basha ◽  
Abu T. Khan
Keyword(s):  
Camphorsulfonic Acid ◽  
One Pot ◽  
Three Component Reaction ◽  
Acid Catalyzed

A new tandem synthesis of bis(β,β′-dialkoxy carbonyl) compounds by oxidative cleavage of aziridines under metal-free conditions

2020 ◽  
Vol 18 (3) ◽  
pp. 551-556 ◽  
Author(s):  
Satyajit Samanta ◽  
Sougata Santra ◽  
Rana Chatterjee ◽  
Adinath Majee
Keyword(s):  
Carbonyl Compounds ◽  
Oxidative Cleavage ◽  
One Pot ◽  
Metal Free ◽  
One Pot Synthesis ◽  
Carbonyl Derivatives ◽  
Tandem Synthesis

One-pot synthesis of bis(β,β′-dialkoxy carbonyl) derivatives has been reported by the oxidative cleavage of aziridines.

Acid-Catalyzed Multicomponent Tandem Double Cyclization: A One-pot, Metal-free Route to Synthesize Polyfunctional 4,9-Dihydropyrrolo[2,1-b]quinazolines

2016 ◽  
Vol 81 (17) ◽  
pp. 8104-8111 ◽  
Author(s):  
Qun Cai ◽  
Deng-Kui Li ◽  
Rong-Rong Zhou ◽  
Shi-Yi Zhuang ◽  
Jin-Tian Ma ◽  
...  
Keyword(s):  
One Pot ◽  
Metal Free ◽  
Acid Catalyzed

scholarly journals Pentafluoropropionic Acid: An Efficient and Metal-Free Catalyst for the One-Pot Synthesis of Tetrahydrobenzo[b]pyran Derivatives

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Naser Montazeri ◽  
Taghva Noghani ◽  
Mona Ghorchibeigy ◽  
Rozita Zoghi
Keyword(s):  
Reaction Time ◽  
Aromatic Aldehyde ◽  
One Pot ◽  
Short Reaction Time ◽  
Metal Free ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
The One ◽  
High Yields

Pentafluoropropionic acid (PFPA) efficiently catalyzes the one-pot, three-component reaction of aromatic aldehyde, malononitrile, and dimedone to yield tetrahydrobenzo[b]pyran derivatives in high yields. This method is of great value because of its easy processing, short reaction time, environmentally, and high yields.

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