Interference of actinomycin D with the replication of the herpes virus DNA. I. Difference in behaviour of cellular and viral nucleic acid synthesis following treatment with actinomycin D

1966 ◽  
Vol 119 (2) ◽  
pp. 331-340 ◽  
Author(s):  
Gerhard Sauer ◽  
Hans Dieter Orth ◽  
Klaus Munk
Keyword(s):  
Nucleic Acid ◽  
Herpes Virus ◽  
Actinomycin D ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis ◽  
Viral Nucleic Acid ◽  
Herpès Virus

Effect of Actinomycin D on Cellular Nucleic Acid Synthesis and Virus Production

Science ◽  
1961 ◽  
Vol 134 (3478) ◽  
pp. 556-557 ◽  
Author(s):  
E. Reich ◽  
R. M. Franklin ◽  
A. J. Shatkin ◽  
E. L. Tatum
Keyword(s):  
Nucleic Acid ◽  
Actinomycin D ◽  
Virus Production ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis

Viral nucleic acid synthesis in HSV infected neural cells

1979 ◽  
Vol 59 (4) ◽  
pp. 345-355 ◽  
Author(s):  
M. Rice ◽  
L. Holland ◽  
E. K. Wagner
Keyword(s):  
Nucleic Acid ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis ◽  
Neural Cells ◽  
Viral Nucleic Acid

scholarly journals Effect of Actinomycin D and 2-Thiouracil on Floral Induction and Nucleic Acid Synthesis in the Bud in Chenopodium Amaranticolor

1966 ◽  
Vol 19 (6) ◽  
pp. 967 ◽  
Author(s):  
JD Watson ◽  
REF Matthews
Keyword(s):  
Nucleic Acid ◽  
Actinomycin D ◽  
Dark Period ◽  
Floral Induction ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis ◽  
Floral Initiation ◽  
Dark Cycle ◽  
Chenopodium Amaranticolor ◽  
Floral Differentiation

Actinomycin D and 2-thiouracil inhibit floral initiation in C. amaranticolor when applied to plants before the end of the inductive dark period. Actinomycin D does not suppress floral differentiation if it is applied to plants more than 48 hr after the inductive dark cycle, whereas 2-thiouracil retains its ability to interfere with floral differentiation when applied to plants several days after the inductive dark period.

The production of interferon by animal viruses

1971 ◽  
Vol 177 (1046) ◽  
pp. 17-22 ◽  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis ◽  
High Multiplicity ◽  
Multiplicity Of Infection ◽  
Viral Nucleic Acid ◽  
Interferon Inducers ◽  
Adequate Stimulus

The production of interferon by animal viruses is a response to the viral nucleic acid. At high multiplicity of infection the nucleic acid of the infecting virus is an adequate stimulus, while at lower multiplicities, viral nucleic acid synthesis is necessary for subsequent interferon formation. It is not known why viral nucleic acids are such effective interferon inducers, nor is it known how their presence within the cell leads to the formation of interferon. It is most likely that the presence of the viral nucleic acids within the cytoplasm leads to a change in the nucleus, resulting in the transcription and translation of the appropriate gene for interferon.

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