Two-dimensional peptide analysis of myosin heavy chains and actin from single-typed human skeletal muscle fibers

FEBS Letters ◽  
1982 ◽  
Vol 139 (1) ◽  
pp. 45-48 ◽  
Author(s):  
R. Billeter ◽  
C.W. Heizmann ◽  
U. Reist ◽  
H. Howald ◽  
E. Jenny
1973 ◽  
Vol 344 (1) ◽  
pp. 1-12 ◽  
Author(s):  
P. D. Gollnick ◽  
R. B. Armstrong ◽  
C. W. Saubert ◽  
W. L. Sembrowich ◽  
R. E. Shepherd ◽  
...  

2000 ◽  
Vol 279 (5) ◽  
pp. E1191-E1195 ◽  
Author(s):  
M. Gaster ◽  
J. Franch ◽  
P. Staehr ◽  
H. Beck-Nielsen ◽  
T. Smith ◽  
...  

Prompted by our recent observations that GLUT-1 is expressed in fetal muscles, but not in adult muscle fibers, we decided to investigate whether GLUT-1 expression could be reactivated. We studied different stimuli concerning their ability to induce GLUT-1 expression in mature human skeletal muscle fibers. Metabolic stress (obesity, non-insulin-dependent diabetes mellitus), contractile activity (training), and conditions of de- and reinnervation (amyotrophic lateral sclerosis) could not induce GLUT-1 expression in human muscle fibers. However, regenerating muscle fibers in polymyositis expressed GLUT-1. In contrast to GLUT-1, GLUT-4 was expressed in all investigated muscle fibers. Although the significance of GLUT-1 in adult human muscle fibers appears limited, GLUT-1 may be of importance for the glucose supplies in immature and regenerating muscle.


2002 ◽  
Vol 47 (1) ◽  
pp. 20-25 ◽  
Author(s):  
Jing Hu ◽  
Itsuro Higuchi ◽  
Yoshihiro Yoshida ◽  
Tadafumi Shiraishi ◽  
Mitsuhiro Osame

1991 ◽  
Vol 187 (7) ◽  
pp. 857-863 ◽  
Author(s):  
R. Wolf ◽  
H.H. Goebel ◽  
L. Gutmann ◽  
S. Schochet

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